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Gene: Hbs1l (HBS1-like translational GTPase) Rattus norvegicus

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Symbol:

Hbs1l

Name:

HBS1-like translational GTPase

RGD ID:

1308509

Description:

Predicted to enable GTPase activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, no-go decay and rescue of stalled ribosome. Predicted to be located in cytoplasm. Predicted to be part of Dom34-Hbs1 complex. Predicted to be active in cytosolic ribosome. Human ortholog(s) of this gene implicated in beta thalassemia. Orthologous to human HBS1L (HBS1 like translational GTPase); PARTICIPATES IN translation termination pathway; mRNA decay pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; acrylamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Hbs1-like; Hbs1-like (S. cerevisiae); HBS1-like protein; LOC293408

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	HBS1L (HBS1 like translational GTPase)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Hbs1l (Hbs1-like (S. cerevisiae))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Hbs1l (HBS1 like translational GTPase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	HBS1L (HBS1 like translational GTPase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	HBS1L (HBS1 like translational GTPase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Hbs1l (HBS1 like translational GTPase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	HBS1L (HBS1 like translational GTPase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	HBS1L (HBS1 like translational GTPase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Hbs1l (HBS1 like translational GTPase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Hbs1l (HBS1 like translational GTPase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	HBS1L (HBS1 like translational GTPase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Hbs1l (Hbs1-like (S. cerevisiae))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	hbs1l (HBS1-like translational GTPase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	HBS1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PhylomeDB)
Caenorhabditis elegans (roundworm):	K07A12.4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	HBS1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	hbs1l	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	hbs1l	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	17,912,139 - 17,989,651 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	17,912,070 - 17,989,646 (+)	Ensembl				GRCr8
mRatBN7.2	1	16,092,529 - 16,170,082 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	16,092,547 - 16,170,074 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	15,848,285 - 15,925,916 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	21,850,176 - 21,927,805 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	16,073,502 - 16,151,133 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	16,819,170 - 16,896,234 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	16,819,170 - 16,896,219 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	17,974,876 - 18,051,510 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	16,668,214 - 16,736,914 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	14,510,728 - 14,588,123 (+)	NCBI		Celera
RGSC_v3.1	1	16,668,273 - 16,736,974 (+)	NCBI
Cytogenetic Map	1	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

beta thalassemia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (EXP)

acrolein (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

Aroclor 1254 (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Brodifacoum (EXP)

cadmium dichloride (EXP)

caffeine (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

chlorpyrifos (ISO)

curcumin (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

disodium selenite (ISO)

doxorubicin (ISO)

endosulfan (EXP)

enzyme inhibitor (ISO)

fenthion (ISO)

folic acid (ISO)

FR900359 (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

ivermectin (ISO)

leflunomide (ISO)

methoxychlor (EXP)

methylmercury chloride (ISO)

nitric oxide (ISO)

ochratoxin A (EXP,ISO)

ozone (ISO)

paracetamol (ISO)

pentanal (ISO)

phenobarbital (ISO)

progesterone (ISO)

resveratrol (ISO)

S-butyl-DL-homocysteine (S,R)-sulfoximine (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

T-2 toxin (ISO)

tamoxifen (ISO)

thimerosal (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

negative regulation of gene expression (IEA)

nuclear-transcribed mRNA catabolic process, no-go decay (ISO,ISS)

regulation of translation (IEA)

rescue of stalled cytosolic ribosome (ISO)

ribosome disassembly (ISO,ISS)

translation (IBA,IEA)

translational elongation (IEA)

Cellular Component

cytoplasm (IEA)

cytosolic ribosome (ISO)

Dom34-Hbs1 complex (ISO,ISS)

Molecular Function

GTP binding (IEA)

GTPase activity (IBA,IEA)

hydrolase activity (IEA)

nucleotide binding (IEA)

protein binding (ISO)

translation elongation factor activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

mRNA decay pathway (IEA)

translation termination pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Structural view on recycling of archaeal and eukaryotic ribosomes after canonical termination and ribosome rescue.	Franckenberg S, etal., Curr Opin Struct Biol. 2012 Dec;22(6):786-96. doi: 10.1016/j.sbi.2012.08.002. Epub 2012 Sep 29.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Association of SNP in exon 1 of HBS1L with hemoglobin F level in beta0-thalassemia/hemoglobin E.	Pandit RA, etal., Int J Hematol. 2008 Nov;88(4):357-61. doi: 10.1007/s12185-008-0167-3. Epub 2008 Oct 7.
6.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:19056867	PMID:19946888

Genomics

Comparative Map Data

Hbs1l
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	17,912,139 - 17,989,651 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	17,912,070 - 17,989,646 (+)	Ensembl				GRCr8
mRatBN7.2	1	16,092,529 - 16,170,082 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	16,092,547 - 16,170,074 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	15,848,285 - 15,925,916 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	21,850,176 - 21,927,805 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	16,073,502 - 16,151,133 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	16,819,170 - 16,896,234 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	16,819,170 - 16,896,219 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	17,974,876 - 18,051,510 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	16,668,214 - 16,736,914 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	14,510,728 - 14,588,123 (+)	NCBI		Celera
RGSC_v3.1	1	16,668,273 - 16,736,974 (+)	NCBI
Cytogenetic Map	1	p12	NCBI

HBS1L
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	134,960,378 - 135,054,822 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	134,960,378 - 135,103,056 (-)	Ensembl			hg38	GRCh38
GRCh37	6	135,281,516 - 135,375,960 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	135,323,209 - 135,417,715 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	6	135,323,215 - 135,417,715	NCBI
Celera	6	136,021,872 - 136,116,411 (-)	NCBI		Celera
Cytogenetic Map	6	q23.3	NCBI
HuRef	6	132,845,729 - 132,940,277 (-)	NCBI		HuRef
CHM1_1	6	135,543,237 - 135,637,724 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	136,148,628 - 136,243,073 (-)	NCBI		T2T-CHM13v2.0

Hbs1l
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	21,171,876 - 21,244,788 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	21,171,878 - 21,244,797 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	21,295,979 - 21,368,889 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	21,295,979 - 21,368,898 (+)	Ensembl			mm10	GRCm38
MGSCv37	10	21,015,785 - 21,088,695 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	20,996,767 - 21,058,314 (+)	NCBI		MGSCv36	mm8
Celera	10	21,189,454 - 21,263,423 (+)	NCBI		Celera
Cytogenetic Map	10	A3	NCBI
cM Map	10	9.75	NCBI

Hbs1l
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955439	1,683,685 - 1,762,314 (+)	Ensembl
ChiLan1.0	NW_004955439	1,684,466 - 1,762,314 (+)	NCBI	ChiLan1.0	ChiLan1.0

HBS1L
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	154,942,160 - 155,032,510 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	152,847,754 - 152,938,090 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	132,732,351 - 132,826,210 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	136,832,884 - 136,922,957 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	136,832,884 - 136,922,957 (-)	Ensembl			panPan2	panpan1.1

HBS1L
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	27,704,375 - 27,791,376 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	27,695,441 - 27,791,381 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	28,584,758 - 28,671,733 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	27,861,829 - 27,948,018 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	27,860,024 - 27,947,992 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	27,746,364 - 27,833,359 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	27,626,482 - 27,713,519 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	27,937,668 - 28,024,033 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Hbs1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	122,812,710 - 122,900,212 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936560	2,591,821 - 2,679,428 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936560	2,591,925 - 2,679,436 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HBS1L
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	29,018,351 - 29,052,423 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	28,968,778 - 29,052,427 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	32,459,545 - 32,530,004 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HBS1L
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	38,383,405 - 38,478,569 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	38,383,435 - 38,473,429 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666040	10,581,023 - 10,677,947 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hbs1l
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624886	2,605,364 - 2,691,705 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624886	2,606,072 - 2,691,323 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Hbs1l
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	215,217,712 - 215,296,874 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Hbs1l
305 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	69
Count of miRNA genes:	61
Interacting mature miRNAs:	66
Transcripts:	ENSRNOT00000019734
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313090	Bmd69	Bone mineral density QTL 69	4.4	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	5293229	34184556	Rat
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	7746118	52746118	Rat
4889451	Eae29	Experimental allergic encephalomyelitis QTL 29	5.51		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	1	7746121	52746121	Rat
70179	Xhs2	X-ray hypersensitivity QTL 2	3.2		intestine integrity trait (VT:0010554)	post-insult time to onset of moribundity (CMO:0001896)	1	1	43965634	Rat
1354647	Despr8	Despair related QTL 8		0.0000341	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	1	26564886	Rat
1558642	Prcr2	Prostate cancer resistance QTL 2	4.3		prostate integrity trait (VT:0010571)	area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)	1	10379492	55379492	Rat
7421626	Bp360	Blood pressure QTL 360		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	6941022	51941022	Rat
2313070	Bss52	Bone structure and strength QTL 52	4.4	0.0001	body length (VT:0001256)	body length (CMO:0000013)	1	5293229	34184556	Rat
1357401	Bw43	Body weight QTL 43	3.75		body mass (VT:0001259)	body weight (CMO:0000012)	1	6909353	51909353	Rat
631494	Bp95	Blood pressure QTL 95	40	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	17315378	51816258	Rat
1600360	Mcs16	Mammary carcinoma susceptibility QTL 16	2.4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	1	26564886	Rat
5684998	Bss101	Bone structure and strength QTL 101	3.6		tibia strength trait (VT:1000284)	tibia ultimate force (CMO:0001734)	1	6909353	51909353	Rat
5684999	Bss102	Bone structure and strength QTL 102	5.5	7e-07	tibia strength trait (VT:1000284)	tibia stiffness (CMO:0001735)	1	6909353	51909353	Rat
2302038	Pia31	Pristane induced arthritis QTL 31	5.5	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	1	12820494	57820494	Rat
2317755	Glom22	Glomerulus QTL 22	3.8		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	1	1	34184556	Rat
1300170	Rf6	Renal function QTL 6	3.14		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	1	1	28483164	Rat
631508	Sald1	Serum aldosterone level QTL 1	3.7		blood aldosterone amount (VT:0005346)	serum aldosterone level (CMO:0000487)	1	11684464	56684464	Rat
2313053	Bss51	Bone structure and strength QTL 51	3.8	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	5293229	34184556	Rat

Markers in Region

RH128240

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	16,169,677 - 16,169,884 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	16,895,830 - 16,896,036	NCBI	Rnor6.0
Rnor_5.0	1	18,051,119 - 18,051,325	UniSTS	Rnor5.0
RGSC_v3.4	1	16,736,523 - 16,736,729	UniSTS	RGSC3.4
Celera	1	14,587,732 - 14,587,938	UniSTS
RH 3.4 Map	1	148.23	UniSTS
Cytogenetic Map	1	p12	UniSTS

RH130225

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	16,133,511 - 16,133,691 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	16,859,959 - 16,860,138	NCBI	Rnor6.0
Rnor_5.0	1	18,015,248 - 18,015,427	UniSTS	Rnor5.0
RGSC_v3.4	1	16,699,379 - 16,699,558	UniSTS	RGSC3.4
Celera	1	14,551,524 - 14,551,703	UniSTS
RH 3.4 Map	1	148.63	UniSTS
Cytogenetic Map	1	p12	UniSTS

PMC140821P1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	16,104,739 - 16,104,908 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	16,830,491 - 16,830,659	NCBI	Rnor6.0
Rnor_5.0	1	17,986,628 - 17,986,796	UniSTS	Rnor5.0
RGSC_v3.4	1	16,671,140 - 16,671,308	UniSTS	RGSC3.4
Celera	1	14,522,852 - 14,523,020	UniSTS
Cytogenetic Map	1	p12	UniSTS

BF390872

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	16,105,028 - 16,105,188 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	16,830,780 - 16,830,939	NCBI	Rnor6.0
Rnor_5.0	1	17,986,917 - 17,987,076	UniSTS	Rnor5.0
RGSC_v3.4	1	16,671,429 - 16,671,588	UniSTS	RGSC3.4
Celera	1	14,523,141 - 14,523,300	UniSTS
RH 3.4 Map	1	163.6	UniSTS
Cytogenetic Map	1	p12	UniSTS

PMC140821P2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	16,168,810 - 16,168,942 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	16,894,963 - 16,895,094	NCBI	Rnor6.0
Rnor_5.0	1	18,050,252 - 18,050,383	UniSTS	Rnor5.0
RGSC_v3.4	1	16,735,656 - 16,735,787	UniSTS	RGSC3.4
Celera	1	14,586,865 - 14,586,996	UniSTS
Cytogenetic Map	1	p12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001011934	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001439724	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001439725	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001439726	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001439727	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001439728	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001439729	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001439730	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001439731	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017588984	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039106903	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039106909	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039106912	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063285773	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063285777	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063285786	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063285789	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC079463	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000019734 ⟹ ENSRNOP00000019734

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	17,912,110 - 17,989,645 (+)	Ensembl
mRatBN7.2 Ensembl	1	16,092,574 - 16,170,067 (+)	Ensembl
Rnor_6.0 Ensembl	1	16,819,170 - 16,896,219 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000086756 ⟹ ENSRNOP00000072325

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	17,923,653 - 17,988,636 (+)	Ensembl
mRatBN7.2 Ensembl	1	16,104,079 - 16,169,067 (+)	Ensembl
Rnor_6.0 Ensembl	1	16,819,249 - 16,895,650 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096492 ⟹ ENSRNOP00000091699

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	17,912,113 - 17,989,645 (+)	Ensembl
mRatBN7.2 Ensembl	1	16,092,566 - 16,170,067 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113225 ⟹ ENSRNOP00000086834

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	17,912,110 - 17,989,646 (+)	Ensembl
mRatBN7.2 Ensembl	1	16,092,588 - 16,170,074 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114016 ⟹ ENSRNOP00000086972

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	17,912,070 - 17,928,099 (+)	Ensembl
mRatBN7.2 Ensembl	1	16,092,547 - 16,108,201 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116762 ⟹ ENSRNOP00000095992

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	17,912,151 - 17,988,520 (+)	Ensembl
mRatBN7.2 Ensembl	1	16,092,547 - 16,127,931 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000168539 ⟹ ENSRNOP00000110480

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	17,912,107 - 17,989,645 (+)	Ensembl

RefSeq Acc Id:

NM_001011934 ⟹ NP_001011934

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	17,912,151 - 17,989,638 (+)	NCBI
mRatBN7.2	1	16,092,607 - 16,170,069 (+)	NCBI
Rnor_6.0	1	16,819,170 - 16,896,221 (+)	NCBI
Rnor_5.0	1	17,974,876 - 18,051,510 (+)	NCBI
RGSC_v3.4	1	16,668,214 - 16,736,914 (+)	RGD
Celera	1	14,510,728 - 14,588,123 (+)	RGD

Sequence:

show sequence

CCCTCCTGCGGTCCGCGTCTCGTCGGTGTCTGAGCGGAGTTCTTCTGGAAGGGACGGCGGCAGA
CGCCCTCAATGCGCGATGGCCCGGCATCGGAACGTCCGGGGCTATAACTATGATGAAGATTTTG
AAGATGATGACTTGTACGGCCAGTCTGTGGAGGATGACTATTGCATCTCACCATCAACAGCTGC
TCAGTTCATTTACTCACGACGTGACAACCCTGAAGAAGAATATGGTTATGAAGATCTGAAAGAG
TCTTCTAATTCTCTTTTGAATCACCAATTAAGTGAAATCGACCAAGCTCGCCTTTATTCATGCC
TTGATCACATGAGAGAGGTACTGGGGGACGCCGTGCCTGATGACATACTGACTGAGGCAATTCT
GAAACATAAGTTTGATGTGCAGAAGGCGTTGTCGGTGGTTCTGGAACAAGATGGTGTGCAGACT
TTGAAGGAGAAGAGTGAGCGAGCAGTGTGTGCAGGACAGCCTTCAAAAGTTATATCTCGGTCAT
CCCAGAGTGAATCTGAAATTGTGCCAAAAGTTGCAAAGATGACTGTGTCCGGGAAGAAGCAGAC
CATGGGATTTGAAGTGCCCGGCTTACCTTCTGAGGAAAATGGACACAATGTGCGCGCTCCTTAC
AAAGGGCCTCCTGGAGATGATGTGAGCATTGCCTCTCCTAATGTTCCTGAGACCGGCACTCCGA
AATCCACCGCCCACCCTCCCTCCCTTCAGACGTCAGAAGAGCTGGGCTGCACTCCGACACCACT
GAGGAAGTCTGGCAAGCTGAGGCAGCAGATAGACGTGAAAGCGGGATTGGAGAAGCGGCAGGGC
GGGAAGCAGCTCCTCAACTTAGTGGTCATTGGTCATGTTGATGCTGGGAAAAGTACTCTGATGG
GCCATATGCTTTATCTTCTGGGTAATGTAAACAAAAGAACTATGCATAAGTATGAGCAAGAATC
TAAAAAGGCTGGCAAGGCTTCATTTGCATATGCATGGGTCTTGGATGAAACTGGAGAAGAAAGG
GAAAGGGGAGTAACAATGGATGTTGGCATGACGAAGTTTGAAACCACAACCAAAGTTGTTACCT
TAATGGATGCTCCAGGCCATAAGGATTTCATTCCAAACATGATCACAGGAGCAGCCCAGGCTGA
CGTGGCAGTCTTGGTCGTTGATGCCAGCAGGGGAGAATTTGAAGCTGGATTTGAGACGGGAGGA
CAGACCCGAGAGCATGGCCTTTTGGTCCGATCTCTTGGAGTGACGCAGCTTGCTGTGGCTGTCA
ATAAGATGGACCAGGTAAATTGGCAACAAGAAAGATTTCAAGAGATTACTGGAAAACTTGGGCA
CTTTCTCAAGCAAGCAGGTTTTAAGGAGAGTGATGTAGCTTTTATCCCAACCAGCGGTCTGAGT
GGCGAGAATTTAACTTCAAGGTCACAGTCCAGTGACCTCACGAAGTGGTACAAAGGGCTCTGCT
TATTGGAGCAGATTGATTCCTTCAAGCCCCCTCAGCGTTCCATTGACAAACCTTTCAGGTTATG
TGTGTCTGATGTCTTCAAAGATCAAGGATCTGGCTTTTGTGTGACTGGTAAGATTGAAGCCGGC
TATGTCCAGACTGGTGACCGACTGTTAGCCATGCCGCCCAATGAAACCTGTACTGCCAAAGGAA
TCACTCTGCACGACGAACCTGTCGATTGGGCAGCAGCAGGAGATCACGTTAGTCTTACTTTGGT
TGGGATGGATATCATCAAAATCAATGTTGGCTGCATATTTTGTGGACCCAAAGAACCCATTAAA
GCTTGCACTCGCTTCAGAGCCCGGATTCTCATCTTCAATATTGAAGTTCCCATCACTAAAGGCT
TTCCTGTGCTGTTACACTACCAAACCGTCAGTGAGCCTGCTGTTATTAAGCGATTGATTAGTGT
CCTAAACAAAAGTACCGGTGAAGTCACAAAGAAGAAGCCCAAGTTGTTGACCAAGGGCCAGAAT
GCCTTGGTAGAGCTGCAGACACAAAGACCAGTGGCTCTCGAGCTCTACAAAGACTTCAAGGAGC
TGGGGCGGTTTATGCTGCGTTATGGTGGCTCCACGGTAGCTGCTGGCGTTGTCACTGAGATAAA
AGAGTGACGGTCCAGTCCTCCCCACGTTTCCAGATGAGACAGCCCCTGAAGCACTCAGTGGTGC
AGCTAAGGAAACGGCATGCAGTCATGATTGTGTAGATGAGAGAAACTAAAGTTCAGGTAGCTGC
CCACCAGTATTAACGATCACTCCCGCACGGCTTCCAGGCTGCCGGCTTCCAGGCTGCCAGCATT
GGACTCTCGTTCCTTCCTTTTGCGGTGGCAGTAAATGCATTTGTTGTGCTGAGACTGTGAAGAT
CAGAAGACACTTAACTCAGTGGACTCAACCTCCAGCCAAGCCAAAACCAGAAGCCTCTGTTTTC
ACTCTCCTGCTGTGTGTGTTCTAAGGAAGCCTATCTTACTGGGGCTGGGAGAGTCCATCTGTGA
CCTGGTGCTTTTTTTGGTTAACACTAAGAAAAGATTTAGTGAAGGTAACAGAGTAAAGCTATTT
TGTGCTGAAAATGAAACCGTCCATCTAGTCTGCCTTCTGGAGTGTGATGGGAAGTGACGGACAC
CTGTTCTTAGGTCACAAAGATACTATTTAAGTTGAAAAGCCAGCTAATAAAATGCCTTAGTTTG
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039106903 ⟹ XP_038962831

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	17,912,139 - 17,989,651 (+)	NCBI
mRatBN7.2	1	16,092,529 - 16,170,082 (+)	NCBI

RefSeq Acc Id:

XM_039106909 ⟹ XP_038962837

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	17,912,139 - 17,989,651 (+)	NCBI
mRatBN7.2	1	16,092,529 - 16,170,082 (+)	NCBI

RefSeq Acc Id:

XM_039106912 ⟹ XP_038962840

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	17,912,139 - 17,930,006 (+)	NCBI
mRatBN7.2	1	16,092,529 - 16,110,719 (+)	NCBI

RefSeq Acc Id:

XM_063285773 ⟹ XP_063141843

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	17,912,139 - 17,989,651 (+)	NCBI

RefSeq Acc Id:

XM_063285777 ⟹ XP_063141847

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	17,912,139 - 17,989,651 (+)	NCBI

RefSeq Acc Id:

XM_063285786 ⟹ XP_063141856

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	17,924,746 - 17,989,651 (+)	NCBI

RefSeq Acc Id:

XM_063285789 ⟹ XP_063141859

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	17,925,782 - 17,989,651 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001011934	(Get FASTA)	NCBI Sequence Viewer
	NP_001426653	(Get FASTA)	NCBI Sequence Viewer
	NP_001426654	(Get FASTA)	NCBI Sequence Viewer
	NP_001426655	(Get FASTA)	NCBI Sequence Viewer
	NP_001426656	(Get FASTA)	NCBI Sequence Viewer
	NP_001426657	(Get FASTA)	NCBI Sequence Viewer
	NP_001426658	(Get FASTA)	NCBI Sequence Viewer
	NP_001426659	(Get FASTA)	NCBI Sequence Viewer
	NP_001426660	(Get FASTA)	NCBI Sequence Viewer
	XP_038962831	(Get FASTA)	NCBI Sequence Viewer
	XP_038962837	(Get FASTA)	NCBI Sequence Viewer
	XP_038962840	(Get FASTA)	NCBI Sequence Viewer
	XP_063141843	(Get FASTA)	NCBI Sequence Viewer
	XP_063141847	(Get FASTA)	NCBI Sequence Viewer
	XP_063141856	(Get FASTA)	NCBI Sequence Viewer
	XP_063141859	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79463	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000019734
	ENSRNOP00000019734.7
	ENSRNOP00000086834
	ENSRNOP00000086972
	ENSRNOP00000095992
GenBank Protein	Q6AXM7	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001011934 ⟸ NM_001011934

- UniProtKB:

Q6AXM7 (UniProtKB/Swiss-Prot), A0A8I6AGM5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDNPEEEYGYEDLKESSNSL
LNHQLSEIDQARLYSCLDHMREVLGDAVPDDILTEAILKHKFDVQKALSVVLEQDGVQTLKEKS
ERAVCAGQPSKVISRSSQSESEIVPKVAKMTVSGKKQTMGFEVPGLPSEENGHNVRAPYKGPPG
DDVSIASPNVPETGTPKSTAHPPSLQTSEELGCTPTPLRKSGKLRQQIDVKAGLEKRQGGKQLL
NLVVIGHVDAGKSTLMGHMLYLLGNVNKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVT
MDVGMTKFETTTKVVTLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREH
GLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVAFIPTSGLSGENLT
SRSQSSDLTKWYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCVTGKIEAGYVQTG
DRLLAMPPNETCTAKGITLHDEPVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKEPIKACTRF
RARILIFNIEVPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKLLTKGQNALVEL
QTQRPVALELYKDFKELGRFMLRYGGSTVAAGVVTEIKE

hide sequence

Ensembl Acc Id:

ENSRNOP00000019734 ⟸ ENSRNOT00000019734

Ensembl Acc Id:

ENSRNOP00000072325 ⟸ ENSRNOT00000086756

RefSeq Acc Id:	XP_038962831 ⟸ XM_039106903
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038962837 ⟸ XM_039106909
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038962840 ⟸ XM_039106912
- Peptide Label:	isoform X5

Ensembl Acc Id:

ENSRNOP00000086972 ⟸ ENSRNOT00000114016

Ensembl Acc Id:

ENSRNOP00000086834 ⟸ ENSRNOT00000113225

Ensembl Acc Id:

ENSRNOP00000091699 ⟸ ENSRNOT00000096492

Ensembl Acc Id:

ENSRNOP00000095992 ⟸ ENSRNOT00000116762

RefSeq Acc Id:	XP_063141843 ⟸ XM_063285773
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AGM5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063141847 ⟸ XM_063285777
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6AGM5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063141856 ⟸ XM_063285786
- Peptide Label:	isoform X6
- UniProtKB:	A6JPE2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063141859 ⟸ XM_063285789
- Peptide Label:	isoform X6
- UniProtKB:	A6JPE2 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000110480 ⟸ ENSRNOT00000168539

Protein Domains

HBS1-like protein N-terminal tr-type G

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6AXM7-F1-model_v2	AlphaFold	Q6AXM7	1-679	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689516

Promoter ID:

EPDNEW_R41

Type:

multiple initiation site

Name:

Hbs1l_1

Description:

HBS1-like translational GTPase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	16,819,129 - 16,819,189	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308509	AgrOrtholog
BioCyc Gene	G2FUF-62182	BioCyc
Ensembl Genes	ENSRNOG00000014531	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000019734	ENTREZGENE
	ENSRNOT00000019734.8	UniProtKB/Swiss-Prot
	ENSRNOT00000113225	ENTREZGENE
	ENSRNOT00000114016	ENTREZGENE
	ENSRNOT00000116762	ENTREZGENE
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot
	DNA helicase RuvA subunit, C-terminal domain	UniProtKB/Swiss-Prot
	Translation factors	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7122195	IMAGE-MGC_LOAD
InterPro	EFTu-like_2	UniProtKB/Swiss-Prot
	GTP-eEF1A_C	UniProtKB/Swiss-Prot
	HBS1-like_N	UniProtKB/Swiss-Prot
	HBS1-like_N_sf	UniProtKB/Swiss-Prot
	P-loop_NTPase	UniProtKB/Swiss-Prot
	TF_GTP-bd_dom	UniProtKB/Swiss-Prot
	TRAFAC_GTPase_members	UniProtKB/Swiss-Prot
	Transl_B-barrel_sf	UniProtKB/Swiss-Prot
	Transl_elong_EF1A/Init_IF2_C	UniProtKB/Swiss-Prot
KEGG Report	rno:293408	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:95018	IMAGE-MGC_LOAD
NCBI Gene	293408	ENTREZGENE
PANTHER	TRANSLATION FACTOR	UniProtKB/Swiss-Prot
Pfam	GTP-eEF1A_C	UniProtKB/Swiss-Prot
	GTP_EFTU	UniProtKB/Swiss-Prot
	GTP_EFTU_D2	UniProtKB/Swiss-Prot
	HBS1_N	UniProtKB/Swiss-Prot
PhenoGen	Hbs1l	PhenoGen
PRINTS	ELONGATNFCT	UniProtKB/Swiss-Prot
PROSITE	G_TR_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000014531	RatGTEx
Superfamily-SCOP	SSF109732	UniProtKB/Swiss-Prot
	SSF50447	UniProtKB/Swiss-Prot
	SSF50465	UniProtKB/Swiss-Prot
	SSF52540	UniProtKB/Swiss-Prot
UniProt	A0A0G2K2P6_RAT	UniProtKB/TrEMBL
	A0A8I6AGM5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GEG8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GEM5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GLW0_RAT	UniProtKB/TrEMBL
	A0ABK0M4T9_RAT	UniProtKB/TrEMBL
	A6JPD9	ENTREZGENE, UniProtKB/TrEMBL
	A6JPE0	ENTREZGENE, UniProtKB/TrEMBL
	A6JPE2	ENTREZGENE, UniProtKB/TrEMBL
	HBS1L_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2014-05-07	Hbs1l	HBS1-like translational GTPase	Hbs1l	Hbs1-like (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Hbs1l	Hbs1-like (S. cerevisiae)	Hbs1l_predicted	Hbs1-like (S. cerevisiae) (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Hbs1l_predicted	Hbs1-like (S. cerevisiae) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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RGD Manual Annotations

Imported Annotations - KEGG (archival)