Myo10 (myosin X) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Myo10 (myosin X) Rattus norvegicus
Analyze
Symbol: Myo10
Name: myosin X
RGD ID: 1307193
Description: Predicted to enable cytoskeletal protein binding activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and plus-end directed microfilament motor activity. Predicted to be involved in cytoskeleton-dependent intracellular transport; regulation of cell shape; and regulation of filopodium assembly. Predicted to act upstream of or within positive regulation of cell-cell adhesion. Predicted to be located in several cellular components, including filopodium tip; neuronal cell body; and nucleolus. Predicted to be part of myosin complex. Predicted to be active in filopodium. Orthologous to human MYO10 (myosin X); PARTICIPATES IN Fc gamma receptor mediated signaling pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC310178; myosin-X; unconventional myosin-10; unconventional myosin-X; unconventionnal myosin-X
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8277,831,532 - 78,036,137 (+)NCBIGRCr8
mRatBN7.2276,100,989 - 76,305,619 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl276,100,987 - 76,303,030 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx283,221,335 - 83,423,563 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0281,343,060 - 81,545,291 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0276,347,046 - 76,550,445 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0277,868,398 - 78,072,443 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl277,868,412 - 78,071,309 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0297,588,995 - 97,790,396 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4277,183,028 - 77,385,896 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1277,111,353 - 77,314,838 (+)NCBI
Celera271,812,056 - 72,011,101 (+)NCBICelera
Cytogenetic Map2q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-palmitoylglycerol  (ISO)
3,4-dichloroaniline  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
acetamide  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amphetamine  (EXP)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
azoxystrobin  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
cadmium dichloride  (ISO)
CGP 52608  (ISO)
chloroprene  (EXP,ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
dibutyl phthalate  (EXP,ISO)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
folic acid  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
glycidyl methacrylate  (ISO)
glyphosate  (EXP)
imidacloprid  (EXP)
inulin  (ISO)
Lasiocarpine  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
methoxyacetic acid  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
mitomycin C  (ISO)
nickel sulfate  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenol red  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
promegestone  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
Salinomycin  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
sunitinib  (ISO)
tebufenpyrad  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
thiabendazole  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trametinib  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12055636   PMID:16371656   PMID:16894163   PMID:20439720   PMID:23704327  


Genomics

Comparative Map Data
Myo10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8277,831,532 - 78,036,137 (+)NCBIGRCr8
mRatBN7.2276,100,989 - 76,305,619 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl276,100,987 - 76,303,030 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx283,221,335 - 83,423,563 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0281,343,060 - 81,545,291 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0276,347,046 - 76,550,445 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0277,868,398 - 78,072,443 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl277,868,412 - 78,071,309 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0297,588,995 - 97,790,396 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4277,183,028 - 77,385,896 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1277,111,353 - 77,314,838 (+)NCBI
Celera271,812,056 - 72,011,101 (+)NCBICelera
Cytogenetic Map2q22NCBI
MYO10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38516,661,907 - 16,936,288 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl516,661,907 - 16,936,288 (-)EnsemblGRCh38hg38GRCh38
GRCh37516,662,016 - 16,936,397 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36516,715,016 - 16,989,385 (-)NCBINCBI36Build 36hg18NCBI36
Build 34516,718,412 - 16,989,139NCBI
Celera516,686,791 - 16,961,521 (-)NCBICelera
Cytogenetic Map5p15.1NCBI
HuRef516,634,005 - 16,909,126 (-)NCBIHuRef
CHM1_1516,661,893 - 16,936,226 (-)NCBICHM1_1
T2T-CHM13v2.0516,601,148 - 16,875,413 (-)NCBIT2T-CHM13v2.0
Myo10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391525,622,636 - 25,813,759 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1525,622,611 - 25,813,759 (+)EnsemblGRCm39 Ensembl
GRCm381525,622,550 - 25,813,673 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1525,622,525 - 25,813,673 (+)EnsemblGRCm38mm10GRCm38
MGSCv371525,552,305 - 25,743,426 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361525,567,651 - 25,756,950 (+)NCBIMGSCv36mm8
Celera1526,396,055 - 26,587,057 (+)NCBICelera
Cytogenetic Map15B1NCBI
cM Map159.36NCBI
Myo10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554265,727,042 - 5,885,302 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554265,725,766 - 5,885,316 (-)NCBIChiLan1.0ChiLan1.0
MYO10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2416,899,283 - 17,169,889 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1515,052,893 - 15,323,471 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0516,969,146 - 17,239,732 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1516,805,022 - 17,075,001 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl516,804,216 - 17,074,534 (-)Ensemblpanpan1.1panPan2
MYO10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1486,701,907 - 86,792,432 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl486,596,225 - 86,792,257 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha486,115,654 - 86,310,421 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0487,234,383 - 87,429,285 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl487,233,833 - 87,429,284 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1486,757,648 - 86,953,127 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0487,010,925 - 87,189,505 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0487,850,904 - 88,046,417 (+)NCBIUU_Cfam_GSD_1.0
Myo10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213210,344,226 - 210,506,772 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648019,282,085 - 19,443,271 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648019,280,723 - 19,443,267 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYO10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl165,907,116 - 6,094,845 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1165,907,111 - 6,145,485 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2166,353,453 - 6,590,952 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYO10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1416,337,933 - 16,608,115 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl416,334,559 - 16,451,166 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606411,870,730 - 12,140,712 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myo10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475113,518,258 - 13,678,148 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475113,517,132 - 13,719,953 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Myo10
1453 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:268
Count of miRNA genes:142
Interacting mature miRNAs:161
Transcripts:ENSRNOT00000014022, ENSRNOT00000065897
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578777Stresp15Stress response QTL 1520.05blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)259846005104846005Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
631500Bp99Blood pressure QTL 992.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)259324719102755241Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23502311780023117Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
2293676Bmd19Bone mineral density QTL 1910.70.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)243162366111362592Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat
2293682Bmd24Bone mineral density QTL 248.90.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)243162366111362592Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
5684996Bmd85Bone mineral density QTL 854.70.024tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)259324377103795077Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
152025242Bw191Body weight QTL 1913.62body mass (VT:0001259)238573329122609194Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)240067944102785628Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24317101783575226Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607157142209Rat
5684990Bmd82Bone mineral density QTL 822.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)259324377103795077Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1558653Prcr1Prostate cancer resistance QTL 15prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)272532993157142209Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22691781781754745Rat
7411551Bw131Body weight QTL 13129.60.001body mass (VT:0001259)body weight gain (CMO:0000420)267942638112942638Rat
1359034Bp274Blood pressure QTL 274arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)27478666494359546Rat
1558648Smcn1Smooth muscle cell number QTL 10.039blood vessel smooth muscle cell quantity (VT:0010525)aorta smooth muscle cell count per unit vessel length (CMO:0001646)259134147127460910Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
2306903Bp336Blood pressure QTL 3360.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)264366971109366971Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226917817136917119Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)228484589169504100Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)228484589169504100Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23513484188029593Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
1582246Cm60Cardiac mass QTL 605.8heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)25760561276539510Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)259324377141596857Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226917817127469484Rat

Markers in Region
D2Rat204  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2276,136,547 - 76,136,768 (+)MAPPERmRatBN7.2
Rnor_6.0277,904,218 - 77,904,438NCBIRnor6.0
Rnor_5.0297,623,705 - 97,623,925UniSTSRnor5.0
RGSC_v3.4277,217,967 - 77,218,188RGDRGSC3.4
RGSC_v3.4277,217,968 - 77,218,188UniSTSRGSC3.4
RGSC_v3.1277,146,168 - 77,146,587RGD
Celera271,847,481 - 71,847,701UniSTS
SHRSP x BN Map229.7798RGD
SHRSP x BN Map229.7798UniSTS
Cytogenetic Map2q22UniSTS
RH137575  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2276,128,919 - 76,129,090 (+)MAPPERmRatBN7.2
Rnor_6.0277,896,753 - 77,896,923NCBIRnor6.0
Rnor_5.0297,616,240 - 97,616,410UniSTSRnor5.0
RGSC_v3.4277,210,340 - 77,210,510UniSTSRGSC3.4
Celera271,839,853 - 71,840,023UniSTS
RH 3.4 Map2484.6UniSTS
Cytogenetic Map2q22UniSTS
MYO10  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2276,293,717 - 76,293,853 (+)MAPPERmRatBN7.2
Rnor_6.0278,062,004 - 78,062,139NCBIRnor6.0
Rnor_5.0297,779,956 - 97,780,091UniSTSRnor5.0
RGSC_v3.4277,376,586 - 77,376,721UniSTSRGSC3.4
Celera272,001,791 - 72,001,926UniSTS
Cytogenetic Map2q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000014022   ⟹   ENSRNOP00000014022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl276,100,987 - 76,303,030 (+)Ensembl
Rnor_6.0 Ensembl277,868,432 - 78,071,309 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000065897   ⟹   ENSRNOP00000063102
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl276,100,987 - 76,303,030 (+)Ensembl
Rnor_6.0 Ensembl277,868,412 - 78,071,263 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102421   ⟹   ENSRNOP00000096719
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl276,157,154 - 76,303,030 (+)Ensembl
RefSeq Acc Id: NM_001401822   ⟹   NP_001388751
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8277,831,532 - 78,036,137 (+)NCBI
mRatBN7.2276,100,989 - 76,305,619 (+)NCBI
RefSeq Acc Id: XM_039102213   ⟹   XP_038958141
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8277,993,376 - 78,034,943 (+)NCBI
mRatBN7.2276,262,832 - 76,304,164 (+)NCBI
RefSeq Acc Id: XM_039102214   ⟹   XP_038958142
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8277,976,203 - 78,034,943 (+)NCBI
mRatBN7.2276,243,775 - 76,304,164 (+)NCBI
RefSeq Acc Id: XM_039102215   ⟹   XP_038958143
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8277,976,673 - 78,034,943 (+)NCBI
mRatBN7.2276,248,112 - 76,304,164 (+)NCBI
RefSeq Acc Id: XM_039102216   ⟹   XP_038958144
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8277,980,339 - 78,034,943 (+)NCBI
mRatBN7.2276,249,792 - 76,304,164 (+)NCBI
RefSeq Acc Id: XM_039102218   ⟹   XP_038958146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8277,980,012 - 78,034,943 (+)NCBI
mRatBN7.2276,248,895 - 76,304,164 (+)NCBI
RefSeq Acc Id: XM_063281749   ⟹   XP_063137819
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8277,980,339 - 78,034,943 (+)NCBI
RefSeq Acc Id: XM_063281750   ⟹   XP_063137820
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8277,995,586 - 78,034,943 (+)NCBI
Ensembl Acc Id: ENSRNOP00000014022   ⟸   ENSRNOT00000014022
Ensembl Acc Id: ENSRNOP00000063102   ⟸   ENSRNOT00000065897
RefSeq Acc Id: XP_038958142   ⟸   XM_039102214
- Peptide Label: isoform X2
- UniProtKB: A6JMW4 (UniProtKB/TrEMBL),   D3ZZ73 (UniProtKB/TrEMBL),   F1M9V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958143   ⟸   XM_039102215
- Peptide Label: isoform X2
- UniProtKB: A6JMW4 (UniProtKB/TrEMBL),   D3ZZ73 (UniProtKB/TrEMBL),   F1M9V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958146   ⟸   XM_039102218
- Peptide Label: isoform X2
- UniProtKB: A6JMW4 (UniProtKB/TrEMBL),   D3ZZ73 (UniProtKB/TrEMBL),   F1M9V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958144   ⟸   XM_039102216
- Peptide Label: isoform X2
- UniProtKB: A6JMW4 (UniProtKB/TrEMBL),   D3ZZ73 (UniProtKB/TrEMBL),   F1M9V6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958141   ⟸   XM_039102213
- Peptide Label: isoform X1
- UniProtKB: A6JMW4 (UniProtKB/TrEMBL),   D3ZZ73 (UniProtKB/TrEMBL),   F1M9V6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000096719   ⟸   ENSRNOT00000102421
RefSeq Acc Id: NP_001388751   ⟸   NM_001401822
- UniProtKB: D3ZJP6 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063137819   ⟸   XM_063281749
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063137820   ⟸   XM_063281750
- Peptide Label: isoform X2
Protein Domains
FERM   IQ   Myosin motor   MyTH4   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZJP6-F1-model_v2 AlphaFold D3ZJP6 1-2060 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691202
Promoter ID:EPDNEW_R1726
Type:initiation region
Name:Myo10_1
Description:myosin X
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0277,868,434 - 77,868,494EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307193 AgrOrtholog
BioCyc Gene G2FUF-53948 BioCyc
Ensembl Genes ENSRNOG00000010161 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055000221 UniProtKB/Swiss-Prot
  ENSRNOG00060020619 UniProtKB/Swiss-Prot
  ENSRNOG00065015072 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000014022.8 UniProtKB/TrEMBL
  ENSRNOT00000065897.5 UniProtKB/Swiss-Prot
  ENSRNOT00000102421.1 UniProtKB/TrEMBL
  ENSRNOT00055000385 UniProtKB/Swiss-Prot
  ENSRNOT00060036273 UniProtKB/Swiss-Prot
  ENSRNOT00065025044 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.10.820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.5.170 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.5.190 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.58.530 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.80.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.25.40.530 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.850.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.20.240.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin VI head, motor domain, U50 subdomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Actin_motor_Myosin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Band_41_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_central UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FERM_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IQ_motif_EF-hand-BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYO10_CC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_head_motor_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MyoX_FERM_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MyoX_N_SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYSc_Myo10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MyTH4_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MyTH4_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 310178 ENTREZGENE
PANTHER AGAP003327-PA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UNCONVENTIONAL MYOSIN-X UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FERM_M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYO10_CC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_head UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MyTH4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00169 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00612 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RA_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_19 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Myo10 PhenoGen
PRINTS MYOSINHEAVY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FERM_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYOSIN_MOTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYTH4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50096 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010161 RatGTEx
  ENSRNOG00055000221 RatGTEx
  ENSRNOG00060020619 RatGTEx
  ENSRNOG00065015072 RatGTEx
SMART B41 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYSc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MyTH4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00015 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47031 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AR40_RAT UniProtKB/TrEMBL
  A6JMW4 ENTREZGENE, UniProtKB/TrEMBL
  D3ZJP6 ENTREZGENE
  D3ZZ73 ENTREZGENE
  F1M9V6 ENTREZGENE, UniProtKB/TrEMBL
  MYO10_RAT UniProtKB/Swiss-Prot
UniProt Secondary D3ZZ73 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Myo10  myosin X   Myo10_predicted  myosin X (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Myo10_predicted  myosin X (predicted)      Symbol and Name status set to approved 70820 APPROVED