Amigo1 (adhesion molecule with Ig like domain 1)

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Gene: Amigo1 (adhesion molecule with Ig like domain 1) Rattus norvegicus

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Symbol:

Amigo1

Name:

adhesion molecule with Ig like domain 1

RGD ID:

1303079

Description:

Predicted to enable potassium channel regulator activity. Involved in several processes, including axon development; cellular response to L-glutamate; and positive regulation of cell projection organization. Located in neuronal cell body and pericellular basket. Orthologous to human AMIGO1 (adhesion molecule with Ig like domain 1); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

alivin-2; Amigo; AMIGO-1; amphoretin-induced gene and ORF; amphoterin-induced protein 1; transmembrane protein AMIGO

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	198,511,285 - 198,516,744 (+)	NCBI		GRCr8
mRatBN7.2	2	195,823,138 - 195,828,593 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	195,823,042 - 195,829,585 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	203,467,204 - 203,468,685 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	201,349,325 - 201,350,806 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	196,166,274 - 196,167,755 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	210,977,125 - 210,982,582 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	210,977,938 - 210,982,579 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	230,446,215 - 230,451,546 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	203,752,632 - 203,754,113 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	203,715,385 - 203,716,867 (+)	NCBI
Celera	2	188,468,900 - 188,470,381 (+)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

hereditary spastic paraplegia 63 (ISO)

schizophrenia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,4-methylenedioxymethamphetamine (ISO)

acetamide (EXP)

acrylamide (ISO)

all-trans-retinoic acid (ISO)

amiodarone (ISO)

ammonium chloride (EXP)

amphetamine (EXP)

Aroclor 1254 (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

C60 fullerene (EXP)

cadmium dichloride (EXP)

chlorpyrifos (ISO)

cisplatin (ISO)

cocaine (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

FR900359 (ISO)

gentamycin (EXP)

glycidol (EXP)

lead diacetate (ISO)

nickel atom (ISO)

ozone (ISO)

paracetamol (EXP)

perfluorohexanesulfonic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

potassium dichromate (ISO)

Ptaquiloside (ISO)

resveratrol (ISO)

SB 431542 (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

trichostatin A (ISO)

triclosan (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axonal fasciculation (IDA)

axonogenesis (IDA)

brain development (IBA)

cell adhesion (TAS)

cellular response to L-glutamate (IDA)

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (IBA,IPI)

homophilic cell adhesion via plasma membrane adhesion molecules (IPI)

myelination (IEP)

neuron projection fasciculation (IDA)

positive regulation of axonogenesis (IDA)

positive regulation of neuron projection development (IDA)

positive regulation of potassium ion transmembrane transport (ISO,ISS)

positive regulation of synapse assembly (IBA,ISO)

positive regulation of voltage-gated potassium channel activity (IMP)

Cellular Component

dendrite (ISO,ISS)

membrane (IBA)

neuronal cell body (IDA)

neuronal cell body membrane (ISO,ISS)

pericellular basket (IDA)

perikaryon (IEA)

plasma membrane (NAS)

voltage-gated potassium channel complex (ISO,ISS)

Molecular Function

potassium channel regulator activity (ISO,ISS)

protein binding (IPI,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats.	Kuja-Panula J, etal., J Cell Biol 2003 Mar 17;160(6):963-73.
3.	AMIGO is an auxiliary subunit of the Kv2.1 potassium channel.	Peltola MA, etal., EMBO Rep. 2011 Dec 1;12(12):1293-9. doi: 10.1038/embor.2011.204.
4.	AMIGO-Kv2.1 Potassium Channel Complex Is Associated With Schizophrenia-Related Phenotypes.	Peltola MA, etal., Schizophr Bull. 2016 Jan;42(1):191-201. doi: 10.1093/schbul/sbv105. Epub 2015 Aug 3.
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:21938721	PMID:24613359

Genomics

Comparative Map Data

Amigo1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	198,511,285 - 198,516,744 (+)	NCBI		GRCr8
mRatBN7.2	2	195,823,138 - 195,828,593 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	195,823,042 - 195,829,585 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	203,467,204 - 203,468,685 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	201,349,325 - 201,350,806 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	196,166,274 - 196,167,755 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	210,977,125 - 210,982,582 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	210,977,938 - 210,982,579 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	230,446,215 - 230,451,546 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	203,752,632 - 203,754,113 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	203,715,385 - 203,716,867 (+)	NCBI
Celera	2	188,468,900 - 188,470,381 (+)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

AMIGO1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	109,504,178 - 109,509,727 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	109,504,178 - 109,509,738 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	110,046,800 - 110,052,349 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	109,850,969 - 109,853,859 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	108,318,787 - 108,321,677 (-)	NCBI		Celera
Cytogenetic Map	1	p13.3	NCBI
HuRef	1	107,942,365 - 107,945,255 (-)	NCBI		HuRef
CHM1_1	1	110,164,300 - 110,167,190 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	109,536,945 - 109,542,494 (-)	NCBI		T2T-CHM13v2.0

Amigo1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	108,093,605 - 108,099,602 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	108,093,651 - 108,099,602 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	108,186,289 - 108,192,286 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	108,186,335 - 108,192,286 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	107,989,253 - 107,994,695 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	108,314,391 - 108,319,833 (+)	NCBI		MGSCv36	mm8
Celera	3	110,520,189 - 110,525,569 (+)	NCBI		Celera
Cytogenetic Map	3	F2.3	NCBI
cM Map	3	46.86	NCBI

Amigo1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955435	12,924,240 - 12,930,362 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955435	12,918,270 - 12,930,362 (-)	NCBI	ChiLan1.0	ChiLan1.0

AMIGO1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	117,794,747 - 117,800,316 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	116,954,644 - 116,960,222 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	111,881,753 - 111,887,308 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	111,110,361 - 111,115,714 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	111,113,632 - 111,115,113 (-)	Ensembl	panpan1.1		panPan2

AMIGO1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	42,351,373 - 42,356,948 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	42,351,373 - 42,354,204 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	45,126,170 - 45,134,290 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	42,681,888 - 42,690,007 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	42,681,994 - 42,684,093 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	42,414,685 - 42,422,802 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	42,372,526 - 42,380,669 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	42,808,091 - 42,815,651 (+)	NCBI		UU_Cfam_GSD_1.0

Amigo1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	19,115,946 - 19,122,210 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936704	991,306 - 998,198 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936704	992,858 - 998,200 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AMIGO1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	110,620,444 - 110,628,833 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	110,620,429 - 110,631,549 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	121,079,460 - 121,085,286 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

AMIGO1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	24,037,679 - 24,040,566 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	24,038,475 - 24,039,956 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	34,417,175 - 34,422,765 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Amigo1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624772	5,231,266 - 5,236,496 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624772	5,231,266 - 5,236,703 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Amigo1
13 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	639
Count of miRNA genes:	273
Interacting mature miRNAs:	359
Transcripts:	ENSRNOT00000074725
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	114837527	211674221	Rat
1358356	Srcrt1	Stress Responsive Cort QTL1	3.66		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	2	161699179	222436696	Rat
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	168358098	223265385	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118463	226797303	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	81754530	227146641	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	18960362	228801039	Rat
1298076	Bp166	Blood pressure QTL 166		0.0009	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	136445150	202447032	Rat
152025245	Scl81	Serum cholesterol level QTL 81	3.49		blood cholesterol amount (VT:0000180)		2	122609194	206936711	Rat
61458	Bp10	Blood pressure QTL 10	3.42		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	189020722	215287351	Rat
70162	Bp63	Blood pressure QTL 63	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	169745596	214745596	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	114837675	212549332	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	78665619	219826953	Rat
1302793	Bw16	Body weight QTL 16	5	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	2	157142209	202446871	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	43154682	202446871	Rat
2317752	Glom23	Glomerulus QTL 23	3.6		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	2	193452645	245889826	Rat
61469	Bp16	Blood pressure QTL 16	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	169745596	214745596	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	2	135552573	202446871	Rat
1358900	Bw48	Body weight QTL 48	4.88		body mass (VT:0001259)	body weight (CMO:0000012)	2	157142078	211086598	Rat
4889834	Pur24	Proteinuria QTL 24	5.8	0.014	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	184114274	202447032	Rat
1359031	Bp275	Blood pressure QTL 275			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	185876309	219753474	Rat
1581499	Esta2	Estrogen-induced thymic atrophy QTL 2			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	189599258	226936289	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	56043031	202447032	Rat
9589044	Scfw1	Subcutaneous fat weight QTL 1	5.8	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	2	182171407	227171407	Rat
8694435	Bw166	Body weight QTL 166	14.08	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	2	182171407	227171407	Rat
2301966	Bp322	Blood pressure QTL 322	3.58		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150540301	202447032	Rat
1298083	Bp158	Blood pressure QTL 158	2.62		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	189020722	215287351	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118275	202447032	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	81689826	221035911	Rat
1331745	Bp203	Blood pressure QTL 203	4.377		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	189599258	218414891	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
8694194	Abfw1	Abdominal fat weight QTL 1	11.7	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	2	182171407	227171407	Rat
61366	Iddm3	Insulin dependent diabetes mellitus QTL 3	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	189599258	234599258	Rat
1359022	Ppulsi1	Prepulse inhibition QTL 1	3.63		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	2	136916935	213594495	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	249053267	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	78665619	249053267	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	76539322	202447032	Rat
2300189	Bmd48	Bone mineral density QTL 48	5.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	2	179335906	224335906	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	157142078	226277316	Rat
2301408	Kidm36	Kidney mass QTL 36		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	190613715	226808892	Rat
631501	Bp101	Blood pressure QTL 101	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150341684	202446871	Rat
2307174	Activ3	Activity QTL 3	4.83	0.000058	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	2	168594495	213594495	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	141194931	223265385	Rat
71113	Cari2	Carrageenan-induced inflammation QTL 2	2.7	0.009	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	2	141596551	202447032	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	141194931	223265385	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	112456140	212696837	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
724568	Uae13	Urinary albumin excretion QTL 13	4.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	2	143157029	210020885	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1300165	Rf9	Renal function QTL 9	3.28		kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	2	133914684	202447032	Rat
738013	Alc15	Alcohol consumption QTL 15	4.1	0.00022	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	2	184165752	229165752	Rat
61398	Bp50	Blood pressure QTL 50	4.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	189599258	234599258	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	112456140	212696837	Rat
1641925	Alcrsp2	Alcohol response QTL 2			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	221167075	Rat
1354609	Niddm62	Non-insulin dependent diabetes mellitus QTL 62	4.72	0.000006	insulin secretion trait (VT:0003564)	plasma insulin level (CMO:0000342)	2	150540301	202447032	Rat
61417	Cia10	Collagen induced arthritis QTL 10	3.4		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	2	179946951	224946951	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	81754530	222436696	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	46123260	202447032	Rat
8694383	Bw158	Body weight QTL 158	7.69	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	2	182171407	227171407	Rat
7488927	Bp365	Blood pressure QTL 365		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	162765032	207765032	Rat
1598838	Bp290	Blood pressure QTL 290	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	166539266	211539266	Rat
7488925	Bp364	Blood pressure QTL 364		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	160564068	205564068	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	164073756	227146641	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	74786664	206665859	Rat
2293084	Iddm26	Insulin dependent diabetes mellitus QTL 26	2.9		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	174930955	213594495	Rat

Markers in Region

RH132767

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	195,828,303 - 195,828,515 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	210,982,291 - 210,982,502	NCBI	Rnor6.0
Rnor_5.0	2	230,451,257 - 230,451,468	UniSTS	Rnor5.0
RGSC_v3.4	2	203,756,941 - 203,757,152	UniSTS	RGSC3.4
Celera	2	188,473,209 - 188,473,420	UniSTS
RH 3.4 Map	2	1387.7	UniSTS
Cytogenetic Map	2	q34	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001412551	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_206881	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233140	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008761392	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281658	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC121208	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY237729	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC167749	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000074725 ⟹ ENSRNOP00000066608

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	195,823,042 - 195,829,585 (+)	Ensembl
Rnor_6.0 Ensembl	2	210,977,938 - 210,982,579 (+)	Ensembl

RefSeq Acc Id:

NM_001412551 ⟹ NP_001399480

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	198,511,308 - 198,516,742 (+)	NCBI
mRatBN7.2	2	195,823,159 - 195,828,593 (+)	NCBI

RefSeq Acc Id:

NM_206881 ⟹ NP_996764

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	198,512,144 - 198,513,625 (+)	NCBI
mRatBN7.2	2	195,823,995 - 195,825,476 (+)	NCBI
Rnor_6.0	2	210,977,982 - 210,979,463 (+)	NCBI
Rnor_5.0	2	230,446,215 - 230,451,546 (+)	NCBI
RGSC_v3.4	2	203,752,632 - 203,754,113 (+)	RGD
Celera	2	188,468,900 - 188,470,381 (+)	RGD

Sequence:

show sequence

ATGCAACCCCAGCGTGACCTGCGAGGCCTCTGGCTCCTGCTGCTCTCCTTGTTCCTGCTTCTCT
TTGAGGTAGCTAGGGCAGGCCGACCTGTGGTCAGTTGTCCCGCCAATTGCCTGTGCGCCAGCAA
CATCCTCAGCTGCTCCAAGCAGCAGCTACCCAATGTGCCCCAATCTTTGCCGGGCTACACAGCG
CTACTGGACCTCAGCCACAACAACTTGAGCCGGCTGAAGGCTGAGTGGACCCCCACCCGTCTGA
CCAACCTGCACTCCCTGCTGCTGAGCCACAACCACCTGAACTTCATCTCCTCTGAGGCCTTCGT
CCCGGTACCCAACCTTCGGTACCTGGACCTCTCCTCCAACCATCTTCACACGCTGGATGAGTTC
CTGTTCAGCGGCCTGCAGGCACTGGAAGTGCTGCTGCTCTACAATAACCACATTGTGGTGGTGG
ACCGGAATGCCTTCGAGGACATGGCCCAGCTGCAGAAACTCTACCTAAGCCAGAATATGATCTC
TCGATTTCCTCTGGAACTGATCAAGGATGCAAACAGATTACCCAAACTAACGCTCTTGGATCTG
TCCTCCAACAAGCTGAAGAAGTTGCCCCTGACTGACCTGCAGAAATTGCCAGCCTGGGTCAAGA
ATGGGCTGTACCTGCATAACAACCCCCTGGAGTGTGACTGCAAGCTCTACCAGCTCTTTTCACA
CTGGCAGTACCGGCAGCTGAGTTCTGTGATGGACTTCCAGGAGGATCTGTATTGCGTGCACTCC
AAGAAGCTGCATAACGTCTTCAGTCTGGATTTCTTCAATTGCAGCGAGTACAAGGAAAGTGCCT
GGGAGGCTCACCTGGGAGACACCTTGACCATCACGTGCGATACCAAACAGCAAGGGATGACCAA
AGTGTGGGTGACCCCAAGCAATGAGCAGGTGCTAAACCAGGGGGCCAATGGCACGGTGACCGTG
TCCGAGGATGGCAACCTTCATTTTAAAGAGGTGCAGGTTGAGGATGGGGGTGTGTATACCTGCT
ATGCCATGGGGGAGACTTTCAACGAAACACTGTCTGTGGAGTTGAAAGTGTATAACTTCACCTT
GCACGGACACCATGACACCCTCAACACAGCCTATACTACCCTGGTGGGCTGCATCCTCAGTGTG
GTTCTGGTCCTCATATACTTGTACCTCACACCTTGCCGCTGCTGGTGCCGGGGTGTGGAGAAGC
CTTCCAGCCATCAAGGAGATAGCCTCAGCTCTTCTATGCTCAGTACCACACCCAACCATGACCC
TATGGCTGGTGGGGACAAAGATGATGGTTTTGACCGGCGGGTGGCCTTCCTGGAACCTGCTGGA
CCAGGGCAGGGTCAAAATGGCAAACTCAAGCCAGGCAACACTCTGCCGGTGCCCGAGGCAACAG
GCAAGGGCCAACGGAGGATGTCAGATCCAGAGTCGGTCAGCTCGGTCTTTTCTGATACACCCAT
TGTGGTGTGA

hide sequence

RefSeq Acc Id:

XM_006233140 ⟹ XP_006233202

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	198,511,287 - 198,516,744 (+)	NCBI
mRatBN7.2	2	195,823,138 - 195,828,593 (+)	NCBI
Rnor_6.0	2	210,977,125 - 210,982,582 (+)	NCBI
Rnor_5.0	2	230,446,215 - 230,451,546 (+)	NCBI

Sequence:

show sequence

GGCGACGGGCGCGCGCGCGGTGCTCGCTGCCCCCACGCTGCTCCCTCGGCTGGGATCGCGGCGT
CTCCCGCTCGCCGCACTGCTCCACGCCTGGCCCGTGGCTCCGGAGGCGGCAGTCGTGCCAGGTG
GGCTCGGGTGGACAGGCGCGGCGGTCGGGGCGAGGCGGCGGCACGGGTGGACAGCGCGGAACCC
AGCAAGTTCCTCGCAGGCGATGTCGCCGGGCGCGGGCCCCTGCGTACGCCGGGCGCCGTGACAG
GCCAGCCGGGGAGGCGCGGACGGGGGAGGCCGCGACGGAGCTCCCGGACTGGCCATGGGCTGAG
CCGCATCCTCACGGAGCAGAACATGCCGGGGTGACTCTCTCCCAGATCCCGTGGCCTTCCTCGC
TCTCCCCAGTGACACTATGCAACCCCAGCGTGACCTGCGAGGCCTCTGGCTCCTGCTGCTCTCC
TTGTTCCTGCTTCTCTTTGAGGTAGCTAGGGCAGGCCGACCTGTGGTCAGTTGTCCCGCCAATT
GCCTGTGCGCCAGCAACATCCTCAGCTGCTCCAAGCAGCAGCTACCCAATGTGCCCCAATCTTT
GCCGGGCTACACAGCGCTACTGGACCTCAGCCACAACAACTTGAGCCGGCTGAAGGCTGAGTGG
ACCCCCACCCGTCTGACCAACCTGCACTCCCTGCTGCTGAGCCACAACCACCTGAACTTCATCT
CCTCTGAGGCCTTCGTCCCGGTACCCAACCTTCGGTACCTGGACCTCTCCTCCAACCATCTTCA
CACGCTGGATGAGTTCCTGTTCAGCGGCCTGCAGGCACTGGAAGTGCTGCTGCTCTACAATAAC
CACATTGTGGTGGTGGACCGGAATGCCTTCGAGGACATGGCCCAGCTGCAGAAACTCTACCTAA
GCCAGAATATGATCTCTCGCTTTCCTCTGGAACTGATCAAGGATGCAAACAGATTACCCAAACT
AACGCTCTTGGATCTGTCCTCCAACAAGCTGAAGAAGTTGCCCCTGACTGACCTGCAGAAATTG
CCAGCCTGGGTCAAGAATGGGCTGTACCTGCATAACAACCCCCTGGAGTGTGACTGCAAGCTCT
ACCAGCTCTTTTCACACTGGCAGTACCGGCAGCTGAGTTCTGTGATGGACTTCCAGGAGGATCT
GTATTGCGTGCACTCCAAGAAGCTGCATAACGTCTTCAGTCTGGATTTCTTCAATTGCAGCGAG
TACAAGGAAAGTGCCTGGGAGGCTCACCTGGGAGACACCTTGACCATCACGTGCGATACCAAAC
AGCAAGGGATGACCAAAGTGTGGGTGACCCCAAGCAATGAGCAGGTGCTAAACCAGGGGGCCAA
TGGCACGGTGACCGTGTCCGAGGATGGCAACCTTCATTTTAAAGAGGTGCAGGTTGAGGATGGG
GGTGTGTATACCTGCTATGCCATGGGGGAGACTTTCAACGAAACACTGTCTGTGGAGTTGAAAG
TGTATAACTTCACCTTGCACGGACACCATGACACCCTCAACACAGCCTATACTACCCTGGTGGG
CTGCATCCTCAGTGTGGTTCTGGTCCTCATATACTTGTACCTCACACCTTGCCGCTGCTGGTGC
CGGGGTGTGGAGAAGCCTTCCAGCCATCAAGGAGATAGCCTCAGCTCTTCTATGCTCAGTACCA
CACCCAACCATGACCCTATGGCTGGTGGGGACAAAGATGATGGTTTTGACCGGCGGGTGGCCTT
CCTGGAACCTGCTGGACCAGGGCAGGGTCAAAATGGCAAACTCAAGCCAGGCAACACTCTGCCG
GTGCCCGAGGCAACAGGCAAGGGCCAACGGAGGATGTCAGATCCAGAGTCGGTCAGCTCGGTCT
TTTCTGATACACCCATTGTGGTGTGAGCAGTATAGGCTGATGGGGAGGTTCTGCCCCAGGAGAG
GTAGTGTACCCCTGAGGGATATGAGGGGGTGGAAGAGAGGGCTGGCTGCCCAAGGGAGTGGGTT
CCTCCTGACCACCAGGGAATCGGTCATGGGCACAGGAGGAGGCAAGACCCCAGTGAGGGTGTGG
ATGCTGTGAGTTTCACACATGGATATATTCATCCTCAGGCAGATACCACACCCTACCCAAAGCC
TTGGCTATTCTCAGTGTGGTAGAGGAGGAGGGATACGTCTGAGTTGGACAGGAACGAGGAAAAG
GGTGTGGGGAGGAGCAGATTCCCTAAACTTTTTTTGAGGTCATCCCTAGCTCCTTAAGAGAAAA
CCATTTGAAAAACAACTTTTTTTTTCTGTCTCTGCCCACCCACACCTGCGAAGTTGTGTGTTGG
GGGGGCCTCCACAGGAGCCATGCTGGGAAGCTGCAGTGTCTTCTCTGGTCAGGGAGTCGAATTC
ATAGCTAGTGAACTGGAAACCTTTGGAAAATGAGTCAGGAAAAGGCTGAGACCTGGATCAATAC
CACTCTGTAATGCTGCTGTGAGACTTCTCACTAGAGCTGTCTTCTTTCCCTGGGAGTCCTGAGT
AGGTGAATCTTTGCAGGAGCCTGGCCTCTTGCCTGTTAGTTATGGCAGCAATATAGGACATTGT
GTCTGTGCCTTGTCCTGGGGCAGGTGGCACAGTTGGGTACAGAATGAATTAATAGGTCCCTGTC
CTAGCATAAAACTTGTAGATGGGGCATAAATTCCAGGTAGGCTAATTCCCTGGCTGGGAGAAAG
CCTTGATTAGTATTTGTCTCCCAATGTCTATCTGTTGGGACAAGAGTAGGGGACACTGAAGAAG
GAGCATTATGGTGCCTGCCACCACTGTGGCACAAGGGCCATACTTGCTGAGAGAACCGGGAAGA
CCGGCCTGTGATGTAGCAGTCAGCCAGACCTACCTGATCCTTCATGTATGCCATCTCTTCTGTC
AACCTTCTGATGGACTCAGGTGGGGTTCTGAGCCTTCCTCAGACGCTGCTCTGCAAAGGAGGGG
GCAGTGAGACGAGGTCTGGAGATAGACGGGACCTAATGTTTATTTTCTCTCTGCTGACAGGGCT
GCCTCACTCCTGCAAAGCCAAAGTGTGGGATTTCTGTCATCTGAAGGGTTAGAACCTAGTGGTC
TTTTGTCCCACAATGGCGATACAGAGTGTGGCTTAGAGTTCTGCCCTCTCCCACCAGGCACTCA
GGCCGTCTTGTAACTGAGGCGGAAGGGGCACTAAACTTTGAAAAGGAAGGAAGTTCTGCCATAC
CGTTCCTGTCAGTTGGAGATCAGTGCAGTCCTGGCTGTCAGAGCAGAGGGACTTAAAAACAAAC
CCAGCCTTAGCTTCCATCCAGGCTTGCAAGATGCTTTCGGTACAGAGATGACTCTGCCTTGCTG
CATCCCGTGAGCAAACTGCAGGCCCCAGAGGCAGTTGTTCTGAGCTTTGGAAGAGGGGTGAGCA
GGGCAGAGGTGAAAGCGTTCCCTAGCGTTGGTCTTTTCCGGTGTCTTTTCTTTCTCGTTTCCTG
TGGTTGGAAGTCGTCCAGGTCCTCTAGTTTCCTGACCTGCTTTTGAGGTTCTAAGGGGTGTTGT
TTACCTGTGGGTGAGGGCTGCTTAGTGCTGGGAGGGCCTGTCAGGCTGCTTATAAGGACTGGGG
AAGAGAAACTGAAGTAAACATTGTCCCCTGTCTGCTCCTGGGATCTCAAGGCTGCTGTCCATCT
TTTATTAGTAACCTAGTTTTATCAAGAGAGAGGTGCAGCGATCCCCTTTAAGTAGTTGCATGCT
CCTGGGTACGCATGCTCCTAGGTATGCATGCACACCAGCACCTTGACCTCCACCAGGACAGTGA
GTCTGTGGCCCCCTCTGATGCCATCATTCTAGAACAGCTTCCACCCACGCACACAACTTCTCAC
ACACAGTTTTCTTGCACTGCAGGAGAGACAGTGACCATGCCAGGCTCCTCAAATGCACAATCTC
TTGTACTTTAATTTCTGAACACCCTGAATTTTTACCCATATCTCCATGGAGCTGAATCACTTTT
CTGCAGATGCTGGAGTTAGGGGGGACCACACACTGGAGCTTTTGGGAGGTTAGTAAGGTACTAG
CTGGTTCATCGGACTCCTCAGGAACTCTCCTTAAAAACTATATATCTATAAGACAGGAGGCTAG
AACCAGAGCAACGAAGGACTCCGAAGGATGCTGGTGGAGGCTAAGCAGCTCTGAATTGTTCTTC
CTGTGTCCTAATAGACAAGGGTTGGAGAGGAATTGGTTGTATTCCAAAGACTTCTGGGCACTTT
GTCACCAGAGGTCCAAGAGCCAGACCTCCATCAGCAGACTCACAAGGAAATGAGAAAATCTCTT
AGTGGCAGCATCCTCTCCTGATACCATCAAGGGTTGTGAGACTCTTTAAAATGAAAGTCAAATG
AAATTTGCCTTCTGGGGCATTCTAGCTGAGCTTCTGAGGGCCAGGAGGGTCATTTTCTTTTTAA
GTCCTACTCTGAAGCCTAGCTCTCCCTACTATAACAGCTAACTTGGGCCCTAGTTCAAGACACC
TGCAGGACATGTCTGGACGCTCTACCAGGACATTTAACTGATTTCTCTCCTCGTGGTTTCAGTT
CTTATGACCCAACTTTGTCCTTGTAGGGGGGTGTACATGTATGTCTGTATTCCAAAAACATATG
ATCCCATTAGACCTTGGGAAAAAAACGACCAGGTGTAGATATAAGAAAGGCTGGCCTTCACCCC
ATCTATACTCATAAACTATCTCCCAGGAAGGAGAAGCAGGTTCCTCTGGAGACAGGATGTGACA
GGACTCTACAGTCTGTGTAATTATCTGTGATCTTTTTCTTTGCTGTATCTATGGGGCCCCTGGA
GGAGGCCAGGAAGGGTAGACCTGTCTGGGGAGAACAAAGCCGATTTCCGGGTGTGTATGTGTCT
TTGCCTTGTAATTCTCTCTTTCTGTGTCTAGGACTCTTCCTCCCACTGTGTACACCAGGCTGGC
AAACCTCGGAGCCCACGGGCTCTGGAACTAGACAATGACCATTAAACCTGGCTTGAGTCTCTGC
TCTGGCACA

hide sequence

RefSeq Acc Id:

XM_063281658 ⟹ XP_063137728

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	198,511,285 - 198,516,744 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001399480	(Get FASTA)	NCBI Sequence Viewer
	NP_996764	(Get FASTA)	NCBI Sequence Viewer
	XP_006233202	(Get FASTA)	NCBI Sequence Viewer
	XP_063137728	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI67749	(Get FASTA)	NCBI Sequence Viewer
	AAO48950	(Get FASTA)	NCBI Sequence Viewer
	EDL81920	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000066608.1
	ENSRNOP00055028845
	ENSRNOP00060039110
	ENSRNOP00065033135
GenBank Protein	Q80ZD7	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_996764 ⟸ NM_206881
- Peptide Label:	precursor
- UniProtKB:	Q80ZD7 (UniProtKB/Swiss-Prot), A6HUY4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MQPQRDLRGLWLLLLSLFLLLFEVARAGRPVVSCPANCLCASNILSCSKQQLPNVPQSLPGYTA LLDLSHNNLSRLKAEWTPTRLTNLHSLLLSHNHLNFISSEAFVPVPNLRYLDLSSNHLHTLDEF LFSGLQALEVLLLYNNHIVVVDRNAFEDMAQLQKLYLSQNMISRFPLELIKDANRLPKLTLLDL SSNKLKKLPLTDLQKLPAWVKNGLYLHNNPLECDCKLYQLFSHWQYRQLSSVMDFQEDLYCVHS KKLHNVFSLDFFNCSEYKESAWEAHLGDTLTITCDTKQQGMTKVWVTPSNEQVLNQGANGTVTV SEDGNLHFKEVQVEDGGVYTCYAMGETFNETLSVELKVYNFTLHGHHDTLNTAYTTLVGCILSV VLVLIYLYLTPCRCWCRGVEKPSSHQGDSLSSSMLSTTPNHDPMAGGDKDDGFDRRVAFLEPAG PGQGQNGKLKPGNTLPVPEATGKGQRRMSDPESVSSVFSDTPIVV hide sequence

RefSeq Acc Id:	XP_006233202 ⟸ XM_006233140
- Peptide Label:	isoform X1
- UniProtKB:	Q80ZD7 (UniProtKB/Swiss-Prot), A6HUY4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MQPQRDLRGLWLLLLSLFLLLFEVARAGRPVVSCPANCLCASNILSCSKQQLPNVPQSLPGYTA LLDLSHNNLSRLKAEWTPTRLTNLHSLLLSHNHLNFISSEAFVPVPNLRYLDLSSNHLHTLDEF LFSGLQALEVLLLYNNHIVVVDRNAFEDMAQLQKLYLSQNMISRFPLELIKDANRLPKLTLLDL SSNKLKKLPLTDLQKLPAWVKNGLYLHNNPLECDCKLYQLFSHWQYRQLSSVMDFQEDLYCVHS KKLHNVFSLDFFNCSEYKESAWEAHLGDTLTITCDTKQQGMTKVWVTPSNEQVLNQGANGTVTV SEDGNLHFKEVQVEDGGVYTCYAMGETFNETLSVELKVYNFTLHGHHDTLNTAYTTLVGCILSV VLVLIYLYLTPCRCWCRGVEKPSSHQGDSLSSSMLSTTPNHDPMAGGDKDDGFDRRVAFLEPAG PGQGQNGKLKPGNTLPVPEATGKGQRRMSDPESVSSVFSDTPIVV hide sequence

Ensembl Acc Id:

ENSRNOP00000066608 ⟸ ENSRNOT00000074725

RefSeq Acc Id:	NP_001399480 ⟸ NM_001412551
- Peptide Label:	precursor
- UniProtKB:	Q80ZD7 (UniProtKB/Swiss-Prot), A6HUY4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137728 ⟸ XM_063281658
- Peptide Label:	isoform X1
- UniProtKB:	Q80ZD7 (UniProtKB/Swiss-Prot), A6HUY4 (UniProtKB/TrEMBL)

Protein Domains

Ig-like Ig-like C2-type LRRCT LRRNT

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q80ZD7-F1-model_v2	AlphaFold	Q80ZD7	1-493	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1303079	AgrOrtholog
BioCyc Gene	G2FUF-51629	BioCyc
Ensembl Genes	ENSRNOG00000045665	Ensembl, UniProtKB/Swiss-Prot
	ENSRNOG00055020836	UniProtKB/Swiss-Prot
	ENSRNOG00060027117	UniProtKB/Swiss-Prot
	ENSRNOG00065023718	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000074725.2	UniProtKB/Swiss-Prot
	ENSRNOT00055035565	UniProtKB/Swiss-Prot
	ENSRNOT00060047026	UniProtKB/Swiss-Prot
	ENSRNOT00065040644	UniProtKB/Swiss-Prot
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot
	3.80.10.10	UniProtKB/Swiss-Prot
	Immunoglobulins	UniProtKB/TrEMBL
	Ribonuclease Inhibitor	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:9021924	IMAGE-MGC_LOAD
InterPro	AMIGO	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cys-rich_flank_reg_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_I-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_sub	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_sub2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Leu-rich_rpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Leu-rich_rpt_typical-subtyp	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LRR_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:187296	IMAGE-MGC_LOAD
NCBI Gene	295365	ENTREZGENE
PANTHER	AMPHOTERIN-INDUCED PROTEIN	UniProtKB/TrEMBL
	AMPHOTERIN-INDUCED PROTEIN 1	UniProtKB/TrEMBL
	PTHR24368	UniProtKB/Swiss-Prot
	PTHR24368:SF1	UniProtKB/Swiss-Prot
Pfam	I-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LRR_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LRR_8	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Amigo1	PhenoGen
PRINTS	LEURICHRPT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	IG_LIKE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LRR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000045665	RatGTEx
	ENSRNOG00055020836	RatGTEx
	ENSRNOG00060027117	RatGTEx
	ENSRNOG00065023718	RatGTEx
SMART	IGc2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LRR_TYP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LRRCT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SM00409	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Immunoglobulin	UniProtKB/TrEMBL
	L domain-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF48726	UniProtKB/Swiss-Prot
UniProt	A6HUY4	ENTREZGENE, UniProtKB/TrEMBL
	AMGO1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-02-26	Amigo1	adhesion molecule with Ig like domain 1	Amigo	amphoretin-induced gene and ORF	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-07-14	Amigo	transmembrane protein AMIGO			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-01-11		amphoretin-induced gene and ORF	Amigo	transmembrane protein AMIGO	Name updated	1299863	PENDING

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar