Advanced Search (OLGA)

Gene: MECR (mitochondrial trans-2-enoyl-CoA reductase) Canis lupus familiaris

Analyze

Symbol:

MECR

Name:

mitochondrial trans-2-enoyl-CoA reductase

RGD ID:

12354039

Description:

ENCODES a protein that exhibits signaling receptor binding (ortholog); INVOLVED IN ceramide biosynthetic process (ortholog); intracellular iron ion homeostasis (ortholog); PARTICIPATES IN fatty acid elongation pathway; ASSOCIATED WITH childhood-onset dystonia with optic atrophy and basal ganglia abnormalities (ortholog); dystonia (ortholog); genetic disease (ortholog); FOUND IN mitochondrion (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

enoyl-[acyl-carrier-protein] reductase, mitochondrial; trans-2-enoyl-CoA reductase, mitochondrial

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	71,369,768 - 71,400,499 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	71,369,806 - 71,400,499 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	67,945,904 - 67,976,636 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	71,930,048 - 71,960,986 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	71,882,756 - 71,961,569 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	68,758,446 - 68,789,364 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	69,766,440 - 69,797,145 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	70,764,275 - 70,795,138 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

childhood-onset dystonia with optic atrophy and basal ganglia abnormalities (ISO)

dystonia (ISO)

genetic disease (ISO)

mitochondrial metabolism disease (ISO)

optic atrophy (ISO)

Optic Atrophy 16 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ceramide biosynthetic process (ISO)

fatty acid biosynthetic process (IEA)

fatty acid metabolic process (IBA,IEA)

intracellular iron ion homeostasis (ISO)

lipid metabolic process (IEA)

Cellular Component

mitochondrion (IBA,IEA)

Molecular Function

enoyl-[acyl-carrier-protein] reductase (NADPH) activity (IEA)

oxidoreductase activity (IEA)

signaling receptor binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

fatty acid elongation pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

MECR
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	71,369,768 - 71,400,499 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	71,369,806 - 71,400,499 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	67,945,904 - 67,976,636 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	71,930,048 - 71,960,986 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	71,882,756 - 71,961,569 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	68,758,446 - 68,789,364 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	69,766,440 - 69,797,145 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	70,764,275 - 70,795,138 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

MECR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	29,167,696 - 29,230,934 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	29,192,657 - 29,230,945 (-)	Ensembl			hg38	GRCh38
GRCh37	1	29,519,169 - 29,557,446 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	29,391,972 - 29,430,041 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	29,340,949 - 29,378,060	NCBI
Celera	1	27,915,536 - 27,953,607 (-)	NCBI		Celera
Cytogenetic Map	1	p35.3	NCBI
HuRef	1	27,771,018 - 27,808,772 (-)	NCBI		HuRef
CHM1_1	1	29,634,784 - 29,672,849 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	29,010,353 - 29,073,591 (-)	NCBI		T2T-CHM13v2.0

Mecr
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	131,570,755 - 131,595,097 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	131,570,781 - 131,595,097 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	131,843,444 - 131,867,787 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	131,843,470 - 131,867,786 (+)	Ensembl			mm10	GRCm38
MGSCv37	4	131,399,386 - 131,423,702 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	131,115,547 - 131,139,843 (+)	NCBI		MGSCv36	mm8
Celera	4	130,003,983 - 130,028,300 (+)	NCBI		Celera
Cytogenetic Map	4	D2.3	NCBI
cM Map	4	64.52	NCBI

Mecr
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	149,313,765 - 149,339,964 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	149,313,774 - 149,342,825 (+)	Ensembl				GRCr8
mRatBN7.2	5	144,029,684 - 144,056,373 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	144,029,731 - 144,055,863 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	146,735,265 - 146,760,951 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	148,505,113 - 148,530,799 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	148,492,992 - 148,518,688 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	150,001,281 - 150,027,407 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	150,001,281 - 150,027,049 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	153,680,447 - 153,709,833 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	150,700,130 - 150,725,219 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	142,473,660 - 142,499,247 (+)	NCBI		Celera
RGSC_v3.1	5	150,710,168 - 150,735,258 (+)	NCBI
Cytogenetic Map	5	q36	NCBI

Mecr
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	8,185,550 - 8,218,950 (-)	Ensembl
ChiLan1.0	NW_004955452	8,185,550 - 8,218,711 (-)	NCBI	ChiLan1.0	ChiLan1.0

MECR
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	197,612,263 - 197,649,385 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	196,731,579 - 196,770,545 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	28,463,466 - 28,501,518 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	29,490,312 - 29,527,351 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	29,490,318 - 29,527,704 (-)	Ensembl			panPan2	panpan1.1

Mecr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	47,317,294 - 47,358,927 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	13,147,938 - 13,183,770 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	13,146,572 - 13,183,707 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MECR
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	86,094,423 - 86,131,682 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	86,094,383 - 86,131,691 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	79,986,968 - 80,018,140 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MECR
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	103,591,944 - 103,630,253 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	103,591,944 - 103,629,102 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666033	12,899,612 - 12,938,148 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mecr
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	12,954,115 - 12,989,755 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624764	12,954,673 - 12,989,711 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Mecr
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	26,385,151 - 26,411,117 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in MECR
301 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005617689	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005617690	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022412444	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038470505	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038470506	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038470507	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038470508	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038531348	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038531349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038531350	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038531351	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038595573	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038595574	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038595576	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038595577	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038659648	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038659649	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038659650	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038659652	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_535334	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000018498 ⟹ ENSCAFP00000017131

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	2	71,369,806 - 71,400,499 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845014402 ⟹ ENSCAFP00845011154

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	71,882,756 - 71,961,569 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845014461 ⟹ ENSCAFP00845011202

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	2	71,930,032 - 71,960,791 (+)	Ensembl

RefSeq Acc Id:

XM_005617689 ⟹ XP_005617746

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	2	71,369,768 - 71,400,499 (+)	NCBI
Dog10K_Boxer_Tasha	2	67,945,904 - 67,976,636 (+)	NCBI

Sequence:

show sequence

GGATGACGTCAGCGCGTTGTCGGGCTCCGAGATTCTGCCGGAAGCATGTGGGGCCGCGGCGCGC
TGTTGCGGACGCGAACCCCGTCCCTCGCTTGGGGCCGCGGCTGGTCTGCCGCCGCTCCCTGCTC
CGCACCTGCGGAGTCCTCCCGGGTCCGGGCGCTGATCTATGGGCACCATGGGGACCCAGCCAAG
GTCGTCGAGCTGAAGAACCTGGAGCTGGCTGCTGTGGGCGGATCAGACGTCCATGTGAAGATGC
TGGCGGCCCCTATCAATCCATCTGACATAAATATGATCCAAGGAAATTATGGCCTCCTTCCCAA
GCTGCCTGCTGTTGGAGGGAATGAAGGCGTTGGACAGGTGGTAGCAGTGGGCGGCAGTGTGACT
GGGGTGAAGCCAGGAGACTGGGTGATTCCAGCAAATGCCGGTTTGGGAGACTGGGTCATCCAGA
ATGCATCCAACAGTGGAGTAGGGCAAGCAGTCATCCAGATCGCCGCAGCCCTAGGCCTAAGGAC
CATCAATGTAGTCCGAGACAGACCTGACCTCCAGGAGCTGACTGATAGACTGAAGAGTCTGGGG
GCCGAGCATGTTCTCACAGAAGAGGAGTTAAGAAAGCATGAGATGAAAAACTTCTTTAAGGATA
TGCCCCAGCCTCGGCTTGCTCTCAACTGTGTTGGCGGGAAAAGCTCCACAGAGCTGCTGCGACA
CTTAGCGCCTGGGGGAACCATGGTGACCTACGGGGGAATGGCCAAGCAGCCCGTCATAGCTTCT
GTGAGCCAGCTCATTTTTAAGGATCTCAAACTTCGAGGCTTTTGGTTGTCCCAGTGGAAGAAGG
ATCACAGTCCAGCCCAGTTCAAGGAGCTGATCCTCACGCTGTGCGGTCTCATCGGCCGAGGCCA
GCTCACAGCGCCCGCCTGCTCCGAGGTCCCACTGCAGGATTACGAGCGTGCCTTGGAAGCCTCA
ATGCAGCCCTTCGTGTCTTCGAAGCAGATTCTCACCATGTGCTAATTGCAGAGGAGCTGGAGTG
AGTTGGGAGGGGACATGGATCAGCAGGACTGGTTTCCGGCCCCTTAGTCAGGGCTCTCAGCCTT
CCCCAGGCTGACCTTTCCTCATTGTCACTTCCGACTGGGCGGGTTGTGAAACTAGCCAAGGCTT
CCCCCAGGGCCAGCCCCAGGGTATCTAATAAAGTCTGAACTTCCTAAAAACAAACACATATAAA

hide sequence

RefSeq Acc Id:

XM_005617690 ⟹ XP_005617747

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	2	71,377,317 - 71,400,493 (+)	NCBI
Dog10K_Boxer_Tasha	2	67,953,436 - 67,976,636 (+)	NCBI

Sequence:

show sequence

GGTATCCTTGACGACGCTGTTAGAACTGTGCGCAGAACAGCAGTGTCTGTGGTGTTAATGGCAT
TCCACGGGGCAGGCTGGGGCCGGTCTCCCTGGTGAGATGCAGCTGGACCAACATACCTCCTGCC
AGGCTGAAGAACCTGGAGCTGGCTGCTGTGGGCGGATCAGACGTCCATGTGAAGATGCTGGCGG
CCCCTATCAATCCATCTGACATAAATATGATCCAAGGAAATTATGGCCTCCTTCCCAAGCTGCC
TGCTGTTGGAGGGAATGAAGGCGTTGGACAGGTGGTAGCAGTGGGCGGCAGTGTGACTGGGGTG
AAGCCAGGAGACTGGGTGATTCCAGCAAATGCCGGTTTGGGAACCTGGCGGACCGAGGCTGTGT
TCAGTGAGGAAGCACTGATCGGAGTTCCAAGTGACATCCCTCTTCAGAGTGCTGCCACCCTGGG
TGTCAATCCCTGCACAGCCTACAGGATGTTGATGGATTTTGAGCAGCTACAGCCAGGAGACTGG
GTCATCCAGAATGCATCCAACAGTGGAGTAGGGCAAGCAGTCATCCAGATCGCCGCAGCCCTAG
GCCTAAGGACCATCAATGTAGTCCGAGACAGACCTGACCTCCAGGAGCTGACTGATAGACTGAA
GAGTCTGGGGGCCGAGCATGTTCTCACAGAAGAGGAGTTAAGAAAGCATGAGATGAAAAACTTC
TTTAAGGATATGCCCCAGCCTCGGCTTGCTCTCAACTGTGTTGGCGGGAAAAGCTCCACAGAGC
TGCTGCGACACTTAGCGCCTGGGGGAACCATGGTGACCTACGGGGGAATGGCCAAGCAGCCCGT
CATAGCTTCTGTGAGCCAGCTCATTTTTAAGGATCTCAAACTTCGAGGCTTTTGGTTGTCCCAG
TGGAAGAAGGATCACAGTCCAGCCCAGTTCAAGGAGCTGATCCTCACGCTGTGCGGTCTCATCG
GCCGAGGCCAGCTCACAGCGCCCGCCTGCTCCGAGGTCCCACTGCAGGATTACGAGCGTGCCTT
GGAAGCCTCAATGCAGCCCTTCGTGTCTTCGAAGCAGATTCTCACCATGTGCTAATTGCAGAGG
AGCTGGAGTGAGTTGGGAGGGGACATGGATCAGCAGGACTGGTTTCCGGCCCCTTAGTCAGGGC
TCTCAGCCTTCCCCAGGCTGACCTTTCCTCATTGTCACTTCCGACTGGGCGGGTTGTGAAACTA
GCCAAGGCTTCCCCCAGGGCCAGCCCCAGGGTATCTAATAAAGTCTGAACTTCCTAAAAACAAA
CACA

hide sequence

RefSeq Acc Id:

XM_022412444 ⟹ XP_022268152

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	2	71,377,497 - 71,400,499 (+)	NCBI
Dog10K_Boxer_Tasha	2	67,953,641 - 67,976,636 (+)	NCBI

Sequence:

show sequence

AGCTTCAACTCTCCATCTCCTAGACCCTCATCCCTGCTCGACTCTCCTTCCCTCCCACTGCTGT
GAATTTCAGGCAGCACAGAGAAGCTAGGCTATCCAGAAGACAGAGAAGAGAACTGGGAGCAGGC
TGAAGAACCTGGAGCTGGCTGCTGTGGGCGGATCAGACGTCCATGTGAAGATGCTGGCGGCCCC
TATCAATCCATCTGACATAAATATGATCCAAGGAAATTATGGCCTCCTTCCCAAGCTGCCTGCT
GTTGGAGGGAATGAAGGCGTTGGACAGGTGGTAGCAGTGGGCGGCAGTGTGACTGGGGTGAAGC
CAGGAGACTGGGTGATTCCAGCAAATGCCGGTTTGGGAACCTGGCGGACCGAGGCTGTGTTCAG
TGAGGAAGCACTGATCGGAGTTCCAAGTGACATCCCTCTTCAGAGTGCTGCCACCCTGGGTGTC
AATCCCTGCACAGCCTACAGGATGTTGATGGATTTTGAGCAGCTACAGCCAGGAGACTGGGTCA
TCCAGAATGCATCCAACAGTGGAGTAGGGCAAGCAGTCATCCAGATCGCCGCAGCCCTAGGCCT
AAGGACCATCAATGTAGTCCGAGACAGACCTGACCTCCAGGAGCTGACTGATAGACTGAAGAGT
CTGGGGGCCGAGCATGTTCTCACAGAAGAGGAGTTAAGAAAGCATGAGATGAAAAACTTCTTTA
AGGATATGCCCCAGCCTCGGCTTGCTCTCAACTGTGTTGGCGGGAAAAGCTCCACAGAGCTGCT
GCGACACTTAGCGCCTGGGGGAACCATGGTGACCTACGGGGGAATGGCCAAGCAGCCCGTCATA
GCTTCTGTGAGCCAGCTCATTTTTAAGGATCTCAAACTTCGAGGCTTTTGGTTGTCCCAGTGGA
AGAAGGATCACAGTCCAGCCCAGTTCAAGGAGCTGATCCTCACGCTGTGCGGTCTCATCGGCCG
AGGCCAGCTCACAGCGCCCGCCTGCTCCGAGGTCCCACTGCAGGATTACGAGCGTGCCTTGGAA
GCCTCAATGCAGCCCTTCGTGTCTTCGAAGCAGATTCTCACCATGTGCTAATTGCAGAGGAGCT
GGAGTGAGTTGGGAGGGGACATGGATCAGCAGGACTGGTTTCCGGCCCCTTAGTCAGGGCTCTC
AGCCTTCCCCAGGCTGACCTTTCCTCATTGTCACTTCCGACTGGGCGGGTTGTGAAACTAGCCA
AGGCTTCCCCCAGGGCCAGCCCCAGGGTATCTAATAAAGTCTGAACTTCCTAAAAACAAACACA
TATAAA

hide sequence

RefSeq Acc Id:

XM_038470505 ⟹ XP_038326433

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	2	68,758,447 - 68,789,364 (+)	NCBI

RefSeq Acc Id:

XM_038470506 ⟹ XP_038326434

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	2	68,758,446 - 68,789,364 (+)	NCBI

RefSeq Acc Id:

XM_038470507 ⟹ XP_038326435

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	2	68,765,992 - 68,789,364 (+)	NCBI

RefSeq Acc Id:

XM_038470508 ⟹ XP_038326436

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	2	68,766,197 - 68,789,364 (+)	NCBI

RefSeq Acc Id:

XM_038531348 ⟹ XP_038387276

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	2	70,764,276 - 70,795,138 (+)	NCBI

RefSeq Acc Id:

XM_038531349 ⟹ XP_038387277

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	2	70,764,275 - 70,795,138 (+)	NCBI

RefSeq Acc Id:

XM_038531350 ⟹ XP_038387278

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	2	70,771,819 - 70,795,138 (+)	NCBI

RefSeq Acc Id:

XM_038531351 ⟹ XP_038387279

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	2	70,772,024 - 70,795,138 (+)	NCBI

RefSeq Acc Id:

XM_038595573 ⟹ XP_038451501

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	2	69,766,441 - 69,797,145 (+)	NCBI

RefSeq Acc Id:

XM_038595574 ⟹ XP_038451502

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	2	69,766,440 - 69,797,145 (+)	NCBI

RefSeq Acc Id:

XM_038595576 ⟹ XP_038451504

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	2	69,773,966 - 69,797,145 (+)	NCBI

RefSeq Acc Id:

XM_038595577 ⟹ XP_038451505

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	2	69,774,171 - 69,797,145 (+)	NCBI

RefSeq Acc Id:

XM_038659648 ⟹ XP_038515576

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	2	71,930,049 - 71,960,986 (+)	NCBI

RefSeq Acc Id:

XM_038659649 ⟹ XP_038515577

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	2	71,930,048 - 71,960,986 (+)	NCBI

RefSeq Acc Id:

XM_038659650 ⟹ XP_038515578

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	2	71,937,606 - 71,960,986 (+)	NCBI

RefSeq Acc Id:

XM_038659652 ⟹ XP_038515580

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	2	71,937,811 - 71,960,986 (+)	NCBI

RefSeq Acc Id:

XM_535334 ⟹ XP_535334

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	2	71,369,769 - 71,400,499 (+)	NCBI
Dog10K_Boxer_Tasha	2	67,945,905 - 67,976,636 (+)	NCBI

Sequence:

show sequence

GATGACGTCAGCGCGTTGTCGGGCTCCGAGATTCTGCCGGAAGCATGTGGGGCCGCGGCGCGCT
GTTGCGGACGCGAACCCCGTCCCTCGCTTGGGGCCGCGGCTGGTCTGCCGCCGCTCCCTGCTCC
GCACCTGCGGAGTCCTCCCGGGTCCGGGCGCTGATCTATGGGCACCATGGGGACCCAGCCAAGG
TCGTCGAGCTGAAGAACCTGGAGCTGGCTGCTGTGGGCGGATCAGACGTCCATGTGAAGATGCT
GGCGGCCCCTATCAATCCATCTGACATAAATATGATCCAAGGAAATTATGGCCTCCTTCCCAAG
CTGCCTGCTGTTGGAGGGAATGAAGGCGTTGGACAGGTGGTAGCAGTGGGCGGCAGTGTGACTG
GGGTGAAGCCAGGAGACTGGGTGATTCCAGCAAATGCCGGTTTGGGAACCTGGCGGACCGAGGC
TGTGTTCAGTGAGGAAGCACTGATCGGAGTTCCAAGTGACATCCCTCTTCAGAGTGCTGCCACC
CTGGGTGTCAATCCCTGCACAGCCTACAGGATGTTGATGGATTTTGAGCAGCTACAGCCAGGAG
ACTGGGTCATCCAGAATGCATCCAACAGTGGAGTAGGGCAAGCAGTCATCCAGATCGCCGCAGC
CCTAGGCCTAAGGACCATCAATGTAGTCCGAGACAGACCTGACCTCCAGGAGCTGACTGATAGA
CTGAAGAGTCTGGGGGCCGAGCATGTTCTCACAGAAGAGGAGTTAAGAAAGCATGAGATGAAAA
ACTTCTTTAAGGATATGCCCCAGCCTCGGCTTGCTCTCAACTGTGTTGGCGGGAAAAGCTCCAC
AGAGCTGCTGCGACACTTAGCGCCTGGGGGAACCATGGTGACCTACGGGGGAATGGCCAAGCAG
CCCGTCATAGCTTCTGTGAGCCAGCTCATTTTTAAGGATCTCAAACTTCGAGGCTTTTGGTTGT
CCCAGTGGAAGAAGGATCACAGTCCAGCCCAGTTCAAGGAGCTGATCCTCACGCTGTGCGGTCT
CATCGGCCGAGGCCAGCTCACAGCGCCCGCCTGCTCCGAGGTCCCACTGCAGGATTACGAGCGT
GCCTTGGAAGCCTCAATGCAGCCCTTCGTGTCTTCGAAGCAGATTCTCACCATGTGCTAATTGC
AGAGGAGCTGGAGTGAGTTGGGAGGGGACATGGATCAGCAGGACTGGTTTCCGGCCCCTTAGTC
AGGGCTCTCAGCCTTCCCCAGGCTGACCTTTCCTCATTGTCACTTCCGACTGGGCGGGTTGTGA
AACTAGCCAAGGCTTCCCCCAGGGCCAGCCCCAGGGTATCTAATAAAGTCTGAACTTCCTAAAA
ACAAACACATATAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005617746	(Get FASTA)	NCBI Sequence Viewer
	XP_005617747	(Get FASTA)	NCBI Sequence Viewer
	XP_022268152	(Get FASTA)	NCBI Sequence Viewer
	XP_038326433	(Get FASTA)	NCBI Sequence Viewer
	XP_038326434	(Get FASTA)	NCBI Sequence Viewer
	XP_038326435	(Get FASTA)	NCBI Sequence Viewer
	XP_038326436	(Get FASTA)	NCBI Sequence Viewer
	XP_038387276	(Get FASTA)	NCBI Sequence Viewer
	XP_038387277	(Get FASTA)	NCBI Sequence Viewer
	XP_038387278	(Get FASTA)	NCBI Sequence Viewer
	XP_038387279	(Get FASTA)	NCBI Sequence Viewer
	XP_038451501	(Get FASTA)	NCBI Sequence Viewer
	XP_038451502	(Get FASTA)	NCBI Sequence Viewer
	XP_038451504	(Get FASTA)	NCBI Sequence Viewer
	XP_038451505	(Get FASTA)	NCBI Sequence Viewer
	XP_038515576	(Get FASTA)	NCBI Sequence Viewer
	XP_038515577	(Get FASTA)	NCBI Sequence Viewer
	XP_038515578	(Get FASTA)	NCBI Sequence Viewer
	XP_038515580	(Get FASTA)	NCBI Sequence Viewer
	XP_535334	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000017131.4
	ENSCAFP00030010691.1
	ENSCAFP00030010724.1
	ENSCAFP00040002623.1
	ENSCAFP00040002645.1
	ENSCAFP00845011154.1
	ENSCAFP00845011202
	ENSCAFP00845011202.1

RefSeq Acc Id:	XP_535334 ⟸ XM_535334
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0PQJ8 (UniProtKB/TrEMBL), A0A8I3MYP2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MWGRGALLRTRTPSLAWGRGWSAAAPCSAPAESSRVRALIYGHHGDPAKVVELKNLELAAVGGS DVHVKMLAAPINPSDINMIQGNYGLLPKLPAVGGNEGVGQVVAVGGSVTGVKPGDWVIPANAGL GTWRTEAVFSEEALIGVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDWVIQNASNSGVGQA VIQIAAALGLRTINVVRDRPDLQELTDRLKSLGAEHVLTEEELRKHEMKNFFKDMPQPRLALNC VGGKSSTELLRHLAPGGTMVTYGGMAKQPVIASVSQLIFKDLKLRGFWLSQWKKDHSPAQFKEL ILTLCGLIGRGQLTAPACSEVPLQDYERALEASMQPFVSSKQILTMC hide sequence

RefSeq Acc Id:

XP_005617746 ⟸ XM_005617689

- Peptide Label:

isoform X2

- Sequence:

show sequence

MWGRGALLRTRTPSLAWGRGWSAAAPCSAPAESSRVRALIYGHHGDPAKVVELKNLELAAVGGS
DVHVKMLAAPINPSDINMIQGNYGLLPKLPAVGGNEGVGQVVAVGGSVTGVKPGDWVIPANAGL
GDWVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDLQELTDRLKSLGAEHVLTEEELRKHEM
KNFFKDMPQPRLALNCVGGKSSTELLRHLAPGGTMVTYGGMAKQPVIASVSQLIFKDLKLRGFW
LSQWKKDHSPAQFKELILTLCGLIGRGQLTAPACSEVPLQDYERALEASMQPFVSSKQILTMC

hide sequence

RefSeq Acc Id:	XP_005617747 ⟸ XM_005617690
- Peptide Label:	isoform X3
- UniProtKB:	A0A8P0SGH9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLAAPINPSDINMIQGNYGLLPKLPAVGGNEGVGQVVAVGGSVTGVKPGDWVIPANAGLGTWRT EAVFSEEALIGVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDWVIQNASNSGVGQAVIQIA AALGLRTINVVRDRPDLQELTDRLKSLGAEHVLTEEELRKHEMKNFFKDMPQPRLALNCVGGKS STELLRHLAPGGTMVTYGGMAKQPVIASVSQLIFKDLKLRGFWLSQWKKDHSPAQFKELILTLC GLIGRGQLTAPACSEVPLQDYERALEASMQPFVSSKQILTMC hide sequence

RefSeq Acc Id:	XP_022268152 ⟸ XM_022412444
- Peptide Label:	isoform X3
- UniProtKB:	A0A8P0SGH9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLAAPINPSDINMIQGNYGLLPKLPAVGGNEGVGQVVAVGGSVTGVKPGDWVIPANAGLGTWRT EAVFSEEALIGVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDWVIQNASNSGVGQAVIQIA AALGLRTINVVRDRPDLQELTDRLKSLGAEHVLTEEELRKHEMKNFFKDMPQPRLALNCVGGKS STELLRHLAPGGTMVTYGGMAKQPVIASVSQLIFKDLKLRGFWLSQWKKDHSPAQFKELILTLC GLIGRGQLTAPACSEVPLQDYERALEASMQPFVSSKQILTMC hide sequence

Ensembl Acc Id:

ENSCAFP00000017131 ⟸ ENSCAFT00000018498

RefSeq Acc Id:	XP_038326434 ⟸ XM_038470506
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038326433 ⟸ XM_038470505
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038326435 ⟸ XM_038470507
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038326436 ⟸ XM_038470508
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038451502 ⟸ XM_038595574
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038451501 ⟸ XM_038595573
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038451504 ⟸ XM_038595576
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038451505 ⟸ XM_038595577
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038515577 ⟸ XM_038659649
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038515576 ⟸ XM_038659648
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0PQW4 (UniProtKB/TrEMBL), A0A8C0LIK8 (UniProtKB/TrEMBL), A0A8C0PQJ8 (UniProtKB/TrEMBL), A0A8I3MYP2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038515578 ⟸ XM_038659650
- Peptide Label:	isoform X3
- UniProtKB:	A0A8P0SGH9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038515580 ⟸ XM_038659652
- Peptide Label:	isoform X3
- UniProtKB:	A0A8P0SGH9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038387277 ⟸ XM_038531349
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038387276 ⟸ XM_038531348
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0PQJ8 (UniProtKB/TrEMBL), A0A8I3MYP2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038387278 ⟸ XM_038531350
- Peptide Label:	isoform X3
- UniProtKB:	A0A8P0SGH9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038387279 ⟸ XM_038531351
- Peptide Label:	isoform X3
- UniProtKB:	A0A8P0SGH9 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845011154 ⟸ ENSCAFT00845014402

Ensembl Acc Id:

ENSCAFP00845011202 ⟸ ENSCAFT00845014461

Protein Domains

Enoyl reductase (ER)

Promoters

RGD ID:

13682564

Promoter ID:

EPDNEW_C632

Type:

multiple initiation site

Name:

MECR_1

Description:

mitochondrial trans-2-enoyl-CoA reductase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	2	71,369,786 - 71,369,846	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000011663	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030006626	UniProtKB/TrEMBL
	ENSCAFG00040001589	UniProtKB/TrEMBL
	ENSCAFG00845008187	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000018498.5	UniProtKB/TrEMBL
	ENSCAFT00030012223.1	UniProtKB/TrEMBL
	ENSCAFT00030012259.1	UniProtKB/TrEMBL
	ENSCAFT00040003040.1	UniProtKB/TrEMBL
	ENSCAFT00040003066.1	UniProtKB/TrEMBL
	ENSCAFT00845014402.1	UniProtKB/TrEMBL
	ENSCAFT00845014461	ENTREZGENE
	ENSCAFT00845014461.1	UniProtKB/TrEMBL
Gene3D-CATH	Medium-chain alcohol dehydrogenases, catalytic domain	UniProtKB/TrEMBL
	NAD(P)-binding Rossmann-like Domain	UniProtKB/TrEMBL
InterPro	ADH_C	UniProtKB/TrEMBL
	ADH_N	UniProtKB/TrEMBL
	GroES-like_sf	UniProtKB/TrEMBL
	Mito_Enoyl-ACP_Reductase	UniProtKB/TrEMBL
	NAD(P)-bd_dom_sf	UniProtKB/TrEMBL
	PKS_ER	UniProtKB/TrEMBL
NCBI Gene	MECR	ENTREZGENE
PANTHER	ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL	UniProtKB/TrEMBL
	ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL	UniProtKB/TrEMBL
Pfam	ADH_N	UniProtKB/TrEMBL
	ADH_zinc_N	UniProtKB/TrEMBL
SMART	PKS_ER	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50129	UniProtKB/TrEMBL
	SSF51735	UniProtKB/TrEMBL
UniProt	A0A8C0LIK8	ENTREZGENE
	A0A8C0PQJ8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0PQW4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3MYL2_CANLF	UniProtKB/TrEMBL
	A0A8I3MYP2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0SGH9	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:43116	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB