PTGS1 (prostaglandin-endoperoxide synthase 1) - Rat Genome Database

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Pathways
Gene: PTGS1 (prostaglandin-endoperoxide synthase 1) Canis lupus familiaris
Analyze
Symbol: PTGS1
Name: prostaglandin-endoperoxide synthase 1
RGD ID: 12328669
Description: ENCODES a protein that exhibits dioxygenase activity (inferred); heme binding (inferred); metal ion binding (inferred); INVOLVED IN learning (ortholog); maintenance of blood-brain barrier (ortholog); memory (ortholog); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Anaphylaxis (ortholog); autism spectrum disorder (ortholog); FOUND IN nuclear envelope (ortholog); INTERACTS WITH acetylsalicylic acid; antipyrine; diclofenac
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: COX-1; COX-3; COX1; cyclooxygenase; Cyclooxygenase-1; PGH synthase 1; PGHS-1; PHS 1; prostaglandin G/H synthase 1; Prostaglandin H2 synthase 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1960,195,118 - 60,216,847 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl960,195,124 - 60,216,819 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha959,390,579 - 59,412,227 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0961,110,468 - 61,132,351 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl961,110,470 - 61,132,343 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1959,884,516 - 59,906,289 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0960,200,281 - 60,222,098 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0960,289,919 - 60,311,671 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
acetylsalicylic acid pharmacodynamics pathway  (ISO)
antipyrine drug pathway  (ISO)
arachidonic acid metabolic pathway  (ISO)
celecoxib pharmacodynamics pathway  (ISO)
celecoxib pharmacokinetics pathway   (ISO)
cyclooxygenase mediated pathway of arachidonic acid metabolism  (ISO)
diclofenac pharmacodynamics pathway  (ISO)
diflunisal pharmacodynamics pathway  (ISO)
etodolac pharmacodynamics pathway  (ISO)
etoposide pharmacodynamics pathway  (ISO)
etoposide pharmacokinetics pathway  (ISO)
fenoprofen pharmacodynamics pathway  (ISO)
flurbiprofen pharmacodynamics pathway  (ISO)
ibuprofen pharmacodynamics pathway  (ISO)
ibuprofen pharmacokinetics pathway  (ISO)
indometacin pharmacodynamics pathway  (ISO)
indometacin pharmacodynamics pathway  (ISO)
ketoprofen pharmacodynamics pathway  (ISO)
ketorolac pharmacodynamics pathway  (ISO)
leukotriene C4 synthase deficiency pathway  (ISO)
lornoxicam pharmacodynamics pathway  (ISO)
magnesium salicylate pharmacodynamics pathway  (ISO)
mefenamic acid pharmacodynamics pathway  (ISO)
meloxicam pharmacodynamics pathway  (ISO)
nabumetone pharmacodynamics pathway  (ISO)
naproxen pharmacodynamics pathway   (ISO)
paracetamol drug pathway  (ISO)
piroxicam pharmacodynamics pathway   (ISO)
prostanoid biosynthetic pathway  (ISO)
salicylic acid pharmacodynamics pathway  (ISO)
sodium salicylate pharmacodynamics pathway  (ISO)
sulindac pharmacodynamics pathway  (ISO)
tenoxicam pharmacodynamics pathway  (ISO)
tiaprofenic acid pharmacodynamics pathway  (ISO)
tolmetin pharmacodynamics pathway  (ISO)
valdecoxib pharmacodynamics pathway  (ISO)

References
Additional References at PubMed
PMID:12242329   PMID:16341006   PMID:17921331   PMID:19274754   PMID:20207364   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PTGS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1960,195,118 - 60,216,847 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl960,195,124 - 60,216,819 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha959,390,579 - 59,412,227 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0961,110,468 - 61,132,351 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl961,110,470 - 61,132,343 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1959,884,516 - 59,906,289 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0960,200,281 - 60,222,098 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0960,289,919 - 60,311,671 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
PTGS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389122,370,533 - 122,395,703 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9122,370,530 - 122,395,705 (+)Ensemblhg38GRCh38
GRCh379125,132,812 - 125,157,982 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369124,173,050 - 124,197,802 (+)NCBIBuild 36Build 36hg18NCBI36
Build 349122,212,782 - 122,237,535NCBI
Celera995,781,549 - 95,806,298 (+)NCBICelera
Cytogenetic Map9q33.2NCBI
HuRef994,747,532 - 94,772,698 (+)NCBIHuRef
CHM1_19125,280,871 - 125,306,038 (+)NCBICHM1_1
T2T-CHM13v2.09134,568,002 - 134,593,163 (+)NCBIT2T-CHM13v2.0
Ptgs1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39236,106,758 - 36,142,287 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl236,120,438 - 36,142,284 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38236,216,742 - 36,258,593 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl236,230,426 - 36,252,272 (+)Ensemblmm10GRCm38
MGSCv37236,085,946 - 36,107,789 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36236,052,536 - 36,074,271 (+)NCBIMGSCv36mm8
Celera235,934,252 - 35,956,092 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map224.19NCBI
Ptgs1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8339,981,419 - 40,002,993 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl339,981,415 - 40,002,990 (+)EnsemblGRCr8
mRatBN7.2319,584,015 - 19,605,589 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl319,584,015 - 19,605,586 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx322,661,928 - 22,683,470 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0331,246,853 - 31,268,395 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0329,494,672 - 29,516,226 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0315,560,685 - 15,582,339 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl315,560,712 - 15,582,344 (+)Ensemblrn6Rnor6.0
Rnor_5.0320,869,915 - 20,891,512 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4315,343,832 - 15,365,412 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera314,295,836 - 14,317,392 (+)NCBICelera
RGSC_v3.1315,240,203 - 15,261,784 (+)NCBI
Cytogenetic Map3p11NCBI
Ptgs1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554195,678,694 - 5,699,305 (-)Ensembl
ChiLan1.0NW_0049554195,678,750 - 5,699,305 (-)NCBIChiLan1.0ChiLan1.0
PTGS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21116,953,759 - 16,975,988 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1916,953,703 - 16,978,307 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0993,495,365 - 93,517,557 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19121,837,095 - 121,859,283 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9121,837,095 - 121,859,283 (+)EnsemblpanPan2panpan1.1
Ptgs1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947190,976,385 - 190,990,294 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648710,745,327 - 10,758,823 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648710,745,465 - 10,758,812 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTGS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1262,456,155 - 262,483,035 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11262,456,106 - 262,482,159 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21294,753,789 - 294,779,835 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTGS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11217,195,403 - 17,218,450 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1217,192,628 - 17,218,315 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603525,831,631 - 25,856,861 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptgs1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476012,915,206 - 12,937,824 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476012,917,244 - 12,937,858 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ptgs1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1513,224,081 - 13,245,665 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in PTGS1
345 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001003023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005625008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005625009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005625010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005625011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005625012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005625014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022422518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038674926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038674927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038674928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038674929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038674930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF535138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF535139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000032279   ⟹   ENSCAFP00000030061
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl960,195,300 - 60,216,819 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000032287   ⟹   ENSCAFP00000030067
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl960,195,124 - 60,216,763 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000062600   ⟹   ENSCAFP00000054704
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl960,195,124 - 60,216,763 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000062685   ⟹   ENSCAFP00000052626
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl960,195,124 - 60,216,774 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000070785   ⟹   ENSCAFP00000062890
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl960,195,124 - 60,212,575 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000075296   ⟹   ENSCAFP00000044164
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl960,195,124 - 60,212,575 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000080930   ⟹   ENSCAFP00000044458
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl960,195,124 - 60,212,575 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000085706   ⟹   ENSCAFP00000058379
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl960,195,124 - 60,216,750 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845024089   ⟹   ENSCAFP00845018920
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl961,110,470 - 61,132,343 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845024265   ⟹   ENSCAFP00845019067
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl961,110,470 - 61,132,343 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845024287   ⟹   ENSCAFP00845019079
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl961,110,470 - 61,132,343 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845024316   ⟹   ENSCAFP00845019104
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl961,110,470 - 61,132,343 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845024344   ⟹   ENSCAFP00845019128
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl961,110,470 - 61,132,306 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845024350   ⟹   ENSCAFP00845019132
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl961,110,470 - 61,128,067 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845024385   ⟹   ENSCAFP00845019167
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl961,110,470 - 61,125,664 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845024410   ⟹   ENSCAFP00845019189
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl961,110,474 - 61,132,277 (-)Ensembl
RefSeq Acc Id: NM_001003023   ⟹   NP_001003023
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1960,195,120 - 60,216,774 (-)NCBI
Dog10K_Boxer_Tasha959,390,579 - 59,412,227 (-)NCBI
ROS_Cfam_1.0961,110,470 - 61,132,277 (-)NCBI
UMICH_Zoey_3.1959,884,516 - 59,906,289 (-)NCBI
UNSW_CanFamBas_1.0960,200,281 - 60,222,098 (-)NCBI
UU_Cfam_GSD_1.0960,289,919 - 60,311,671 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038674926   ⟹   XP_038530854
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0961,110,468 - 61,127,621 (-)NCBI
RefSeq Acc Id: XM_038674927   ⟹   XP_038530855
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0961,110,857 - 61,127,620 (-)NCBI
RefSeq Acc Id: XM_038674928   ⟹   XP_038530856
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0961,110,857 - 61,132,318 (-)NCBI
RefSeq Acc Id: XM_038674929   ⟹   XP_038530857
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0961,110,857 - 61,132,351 (-)NCBI
RefSeq Acc Id: XM_038674930   ⟹   XP_038530858
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0961,110,857 - 61,132,265 (-)NCBI
RefSeq Acc Id: NP_001003023   ⟸   NM_001003023
- Peptide Label: precursor
- UniProtKB: A0A8C0M635 (UniProtKB/TrEMBL),   A0A8I3NTG8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000062890   ⟸   ENSCAFT00000070785
Ensembl Acc Id: ENSCAFP00000054704   ⟸   ENSCAFT00000062600
Ensembl Acc Id: ENSCAFP00000052626   ⟸   ENSCAFT00000062685
Ensembl Acc Id: ENSCAFP00000044458   ⟸   ENSCAFT00000080930
Ensembl Acc Id: ENSCAFP00000044164   ⟸   ENSCAFT00000075296
Ensembl Acc Id: ENSCAFP00000058379   ⟸   ENSCAFT00000085706
Ensembl Acc Id: ENSCAFP00000030067   ⟸   ENSCAFT00000032287
Ensembl Acc Id: ENSCAFP00000030061   ⟸   ENSCAFT00000032279
RefSeq Acc Id: XP_038530854   ⟸   XM_038674926
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KR96 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038530857   ⟸   XM_038674929
- Peptide Label: isoform X4
- UniProtKB: Q8HZR1 (UniProtKB/Swiss-Prot),   Q8HZR0 (UniProtKB/Swiss-Prot),   F1PBX3 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038530856   ⟸   XM_038674928
- Peptide Label: isoform X3
- UniProtKB: A0A8I3NTG8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038530858   ⟸   XM_038674930
- Peptide Label: isoform X5
- UniProtKB: A0A8C0Q9L9 (UniProtKB/TrEMBL),   A0A8P0TAE2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038530855   ⟸   XM_038674927
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KR96 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845019128   ⟸   ENSCAFT00845024344
Ensembl Acc Id: ENSCAFP00845018920   ⟸   ENSCAFT00845024089
Ensembl Acc Id: ENSCAFP00845019079   ⟸   ENSCAFT00845024287
Ensembl Acc Id: ENSCAFP00845019067   ⟸   ENSCAFT00845024265
Ensembl Acc Id: ENSCAFP00845019132   ⟸   ENSCAFT00845024350
Ensembl Acc Id: ENSCAFP00845019189   ⟸   ENSCAFT00845024410
Ensembl Acc Id: ENSCAFP00845019104   ⟸   ENSCAFT00845024316
Ensembl Acc Id: ENSCAFP00845019167   ⟸   ENSCAFT00845024385
Protein Domains
EGF-like

Promoters
RGD ID:13684849
Promoter ID:EPDNEW_C2917
Type:initiation region
Name:PTGS1_1
Description:prostaglandin-endoperoxide synthase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_C2918  
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1960,216,675 - 60,216,735EPDNEW
RGD ID:13684852
Promoter ID:EPDNEW_C2918
Type:single initiation site
Name:PTGS1_2
Description:prostaglandin-endoperoxide synthase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_C2917  
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1960,216,785 - 60,216,845EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000020263 Ensembl, UniProtKB/Swiss-Prot
  ENSCAFG00040002347 UniProtKB/Swiss-Prot
  ENSCAFG00845013501 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSCAFT00000032279.4 UniProtKB/Swiss-Prot
  ENSCAFT00000032287.6 UniProtKB/Swiss-Prot
  ENSCAFT00000062685.2 UniProtKB/Swiss-Prot
  ENSCAFT00040004500.1 UniProtKB/Swiss-Prot
  ENSCAFT00040004521.1 UniProtKB/Swiss-Prot
  ENSCAFT00040004622.1 UniProtKB/Swiss-Prot
  ENSCAFT00845024089 ENTREZGENE
  ENSCAFT00845024089.1 UniProtKB/Swiss-Prot
  ENSCAFT00845024410 ENTREZGENE
Gene3D-CATH 1.10.640.10 UniProtKB/Swiss-Prot
  Laminin UniProtKB/Swiss-Prot
InterPro EGF-like_dom UniProtKB/Swiss-Prot
  Haem_peroxidase_animal UniProtKB/Swiss-Prot
  Haem_peroxidase_sf UniProtKB/Swiss-Prot
  Haem_peroxidase_sf_animal UniProtKB/Swiss-Prot
  Oxylipin_biosynth_metab UniProtKB/Swiss-Prot
KEGG Report cfa:403544 UniProtKB/Swiss-Prot
NCBI Gene PTGS1 ENTREZGENE
PANTHER PROSTAGLANDIN G/H SYNTHASE UniProtKB/Swiss-Prot
  PTHR11903:SF6 UniProtKB/Swiss-Prot
Pfam An_peroxidase UniProtKB/Swiss-Prot
PRINTS ANPEROXIDASE UniProtKB/Swiss-Prot
PROSITE EGF_3 UniProtKB/Swiss-Prot
  PEROXIDASE_3 UniProtKB/Swiss-Prot
Superfamily-SCOP EGF/Laminin UniProtKB/Swiss-Prot
  SSF48113 UniProtKB/Swiss-Prot
UniProt A0A8C0KR96 ENTREZGENE
  A0A8C0M1C0_CANLF UniProtKB/TrEMBL
  A0A8C0M1D8_CANLF UniProtKB/TrEMBL
  A0A8C0M1F9_CANLF UniProtKB/TrEMBL
  A0A8C0M4M8_CANLF UniProtKB/TrEMBL
  A0A8C0M502_CANLF UniProtKB/TrEMBL
  A0A8C0M5A6_CANLF UniProtKB/TrEMBL
  A0A8C0M635 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PTJ6_CANLF UniProtKB/TrEMBL
  A0A8C0PXV0_CANLF UniProtKB/TrEMBL
  A0A8C0Q062_CANLF UniProtKB/TrEMBL
  A0A8C0Q9L9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RBE9_CANLF UniProtKB/TrEMBL
  A0A8I3NGM1_CANLF UniProtKB/TrEMBL
  A0A8I3NGN0_CANLF UniProtKB/TrEMBL
  A0A8I3NTA0_CANLF UniProtKB/TrEMBL
  A0A8I3NTB9_CANLF UniProtKB/TrEMBL
  A0A8I3NTG8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RXN2_CANLF UniProtKB/TrEMBL
  A0A8I3S0A3_CANLF UniProtKB/TrEMBL
  A0A8P0P453_CANLF UniProtKB/TrEMBL
  A0A8P0TAE2 ENTREZGENE
  F1PBX3 ENTREZGENE
  PGH1_CANLF UniProtKB/Swiss-Prot
  Q8HZR0 ENTREZGENE
  Q8HZR1 ENTREZGENE
UniProt Secondary F1PBX3 UniProtKB/Swiss-Prot
  Q8HZR0 UniProtKB/Swiss-Prot
VGNC ID VGNC:45151 ENTREZGENE