CDC45 (cell division cycle 45) - Rat Genome Database

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Gene: CDC45 (cell division cycle 45) Canis lupus familiaris
Analyze
Symbol: CDC45
Name: cell division cycle 45
RGD ID: 12161246
Description: INVOLVED IN DNA replication (inferred); DNA replication initiation (inferred); ASSOCIATED WITH androgen insensitivity syndrome (ortholog); Androgen Insensitivity Syndrome due to Coactivator Deficiency (ortholog); COVID-19 (ortholog); FOUND IN ciliary basal body (inferred); CMG complex (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CDC45 cell division cycle 45 homolog; CDC45L; cell division control protein 45 homolog; cell division cycle 45 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12629,707,523 - 29,738,599 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2629,707,564 - 29,739,252 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2629,662,567 - 29,693,731 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02631,108,959 - 31,140,135 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2631,109,000 - 31,139,844 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12629,156,284 - 29,187,449 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02628,782,002 - 28,813,128 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02629,867,112 - 29,899,768 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CDC45
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12629,707,523 - 29,738,599 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2629,707,564 - 29,739,252 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2629,662,567 - 29,693,731 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02631,108,959 - 31,140,135 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2631,109,000 - 31,139,844 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12629,156,284 - 29,187,449 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02628,782,002 - 28,813,128 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02629,867,112 - 29,899,768 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
CDC45
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382219,479,466 - 19,520,612 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2219,479,457 - 19,520,612 (+)Ensemblhg38GRCh38
GRCh372219,466,989 - 19,508,135 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362217,847,416 - 17,888,135 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342217,841,969 - 17,882,688NCBI
Celera223,319,674 - 3,360,395 (+)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef223,088,162 - 3,128,966 (+)NCBIHuRef
CHM1_12219,466,920 - 19,507,702 (+)NCBICHM1_1
T2T-CHM13v2.02219,856,299 - 19,897,453 (+)NCBIT2T-CHM13v2.0
Cdc45
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391618,599,202 - 18,632,371 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1618,599,197 - 18,630,737 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381618,780,447 - 18,811,972 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1618,780,447 - 18,811,987 (-)Ensemblmm10GRCm38
MGSCv371618,780,540 - 18,812,065 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361618,694,015 - 18,725,535 (-)NCBIMGSCv36mm8
Celera1619,354,501 - 19,386,029 (-)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.63NCBI
Cdc45
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81195,689,702 - 95,714,980 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1195,689,919 - 95,714,981 (+)EnsemblGRCr8
mRatBN7.21182,185,427 - 82,210,630 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,185,473 - 82,210,619 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1190,917,527 - 90,942,110 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01183,578,747 - 83,603,331 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01182,632,015 - 82,656,850 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01186,328,785 - 86,354,099 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1186,329,012 - 86,358,453 (+)Ensemblrn6Rnor6.0
Rnor_5.01189,431,161 - 89,456,065 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera1180,966,334 - 80,990,943 (+)NCBICelera
Cytogenetic Map11q23NCBI
Cdc45
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544218,514,731 - 18,547,805 (-)Ensembl
ChiLan1.0NW_00495544218,513,398 - 18,548,317 (-)NCBIChiLan1.0ChiLan1.0
CDC45
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22329,104,120 - 29,145,481 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12231,651,826 - 31,693,203 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0222,239,040 - 2,279,807 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12217,913,729 - 17,955,195 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2217,913,729 - 17,955,195 (+)EnsemblpanPan2panpan1.1
Cdc45
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118139,301,628 - 139,333,944 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366193,420,191 - 3,452,436 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366193,420,110 - 3,452,419 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC45
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1451,133,408 - 51,158,606 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11451,133,111 - 51,158,604 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21454,750,436 - 54,775,656 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDC45
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1196,232,610 - 6,275,743 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl196,231,591 - 6,275,294 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666085658,030 - 701,069 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdc45
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624747132,835 - 161,553 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624747132,731 - 161,590 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cdc45
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v144,049,378 - 4,074,361 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in CDC45
452 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005636590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022410838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038437531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038437532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038459035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038512397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038512398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038575897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038575898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038575899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038640109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038640110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_543547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000023166   ⟹   ENSCAFP00000021510
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2629,707,564 - 29,739,252 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845052146   ⟹   ENSCAFP00845040900
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2631,109,000 - 31,139,844 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845052214   ⟹   ENSCAFP00845040953
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2631,109,000 - 31,139,844 (-)Ensembl
RefSeq Acc Id: XM_005636590   ⟹   XP_005636647
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12629,707,523 - 29,738,596 (-)NCBI
Dog10K_Boxer_Tasha2629,662,567 - 29,693,731 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038437531   ⟹   XP_038293459
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02631,108,959 - 31,140,105 (-)NCBI
RefSeq Acc Id: XM_038437532   ⟹   XP_038293460
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02631,108,959 - 31,140,135 (-)NCBI
RefSeq Acc Id: XM_038459035   ⟹   XP_038314963
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2629,662,567 - 29,693,712 (-)NCBI
RefSeq Acc Id: XM_038512397   ⟹   XP_038368325
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12629,156,284 - 29,187,419 (-)NCBI
RefSeq Acc Id: XM_038512398   ⟹   XP_038368326
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12629,156,284 - 29,187,449 (-)NCBI
RefSeq Acc Id: XM_038575897   ⟹   XP_038431825
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02629,867,112 - 29,899,736 (-)NCBI
RefSeq Acc Id: XM_038575898   ⟹   XP_038431826
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02629,867,112 - 29,899,747 (-)NCBI
RefSeq Acc Id: XM_038575899   ⟹   XP_038431827
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02629,867,112 - 29,899,768 (-)NCBI
RefSeq Acc Id: XM_038640109   ⟹   XP_038496037
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02628,782,002 - 28,813,109 (-)NCBI
RefSeq Acc Id: XM_038640110   ⟹   XP_038496038
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02628,782,002 - 28,813,128 (-)NCBI
RefSeq Acc Id: XM_543547   ⟹   XP_543547
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12629,707,523 - 29,738,584 (-)NCBI
Dog10K_Boxer_Tasha2629,662,567 - 29,693,701 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005636647   ⟸   XM_005636590
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PDQ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_543547   ⟸   XM_543547
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NXS2 (UniProtKB/TrEMBL),   A0A8I3Q3M7 (UniProtKB/TrEMBL),   A0A8C0PDQ6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000021510   ⟸   ENSCAFT00000023166
RefSeq Acc Id: XP_038368326   ⟸   XM_038512398
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038368325   ⟸   XM_038512397
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038496038   ⟸   XM_038640110
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038496037   ⟸   XM_038640109
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038293460   ⟸   XM_038437532
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PDQ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038293459   ⟸   XM_038437531
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NXS2 (UniProtKB/TrEMBL),   A0A8I3Q3M7 (UniProtKB/TrEMBL),   A0A8C0PDQ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038314963   ⟸   XM_038459035
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NXS2 (UniProtKB/TrEMBL),   A0A8I3Q3M7 (UniProtKB/TrEMBL),   A0A8C0PDQ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038431827   ⟸   XM_038575899
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PDQ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038431826   ⟸   XM_038575898
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NXS2 (UniProtKB/TrEMBL),   A0A8C0PDQ6 (UniProtKB/TrEMBL),   A0A8I3Q3M7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038431825   ⟸   XM_038575897
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NXS2 (UniProtKB/TrEMBL),   A0A8C0PDQ6 (UniProtKB/TrEMBL),   A0A8I3Q3M7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845040900   ⟸   ENSCAFT00845052146
Ensembl Acc Id: ENSCAFP00845040953   ⟸   ENSCAFT00845052214

Promoters
RGD ID:13688035
Promoter ID:EPDNEW_C6101
Type:single initiation site
Name:CDC45_1
Description:cell division cycle 45
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12629,738,429 - 29,738,489EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000014571 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030020892 UniProtKB/TrEMBL
  ENSCAFG00040022996 UniProtKB/TrEMBL
  ENSCAFG00845029448 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000023166.6 UniProtKB/TrEMBL
  ENSCAFT00030038344.1 UniProtKB/TrEMBL
  ENSCAFT00030038464.1 UniProtKB/TrEMBL
  ENSCAFT00040042961.1 UniProtKB/TrEMBL
  ENSCAFT00040043034.1 UniProtKB/TrEMBL
  ENSCAFT00845052146 ENTREZGENE
  ENSCAFT00845052146.1 UniProtKB/TrEMBL
  ENSCAFT00845052214.1 UniProtKB/TrEMBL
InterPro CDC45 UniProtKB/TrEMBL
NCBI Gene CDC45 ENTREZGENE
PANTHER CELL DIVISION CONTROL PROTEIN 45 HOMOLOG UniProtKB/TrEMBL
  PTHR10507 UniProtKB/TrEMBL
Pfam CDC45 UniProtKB/TrEMBL
UniProt A0A8C0NXS2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PDQ6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TKK3_CANLF UniProtKB/TrEMBL
  A0A8I3Q3M7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3QJR7_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:39007 ENTREZGENE