11696213 | FN1 | fibronectin 1 | ENCODES a protein that exhibits mercury ion binding (ortholog); protease binding (ortholog); INVOLVED IN autophagy (ortholog); blood coagulation, fibrin clot formation (ortholog); cell-matrix adhesion (ortholog); PARTICIPATES IN syndecan signaling pathway; ASSOCIATED WITH acute kidney failure (ortho log); Acute Otitis Media (ortholog); Animal Mammary Neoplasms (ortholog); FOUND IN basement membrane (ortholog); extracellular space (ortholog) | 2B | 102623568 | 102698747 | Bonobo | 217 | symbol | gene, protein-coding, MODEL [RefSeq] |
11863185 | FN3K | fructosamine 3 kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); INVOLVED IN peptidyl-lysine deglycation (ortholog); protein deglycation (ortholog); ASSOCIATED WITH generalized epilepsy (ortholog); FOUND IN cytosol (inferred); mitochondrion (inferred ) | 17 | 77154014 | 77169903 | Bonobo | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
11917182 | FNTA | farnesyltransferase, CAAX box, subunit alpha | ENCODES a protein that exhibits CAAX-protein geranylgeranyltransferase activity (ortholog); heterocyclic compound binding (ortholog); molecular adaptor activity (ortholog); INVOLVED IN enzyme-linked receptor protein signaling pathway (ortholog); negative regulation of apoptotic process (ortholog); n uclear envelope organization (ortholog); ASSOCIATED WITH congenital muscular dystrophy-dystroglycanopathy type A12 (ortholog); Idiopathic Basal Ganglia Calcification 1 (ortholog); IMMUNODEFICIENCY 15 (ortholog); FOUND IN CAAX-protein geranylgeranyltransferase complex (ortholog) | 8 | 42303987 | 42333743 | Bonobo | 72 | symbol | gene, protein-coding, MODEL [RefSeq] |
11821861 | FNTB | farnesyltransferase, CAAX box, subunit beta | ENCODES a protein that exhibits geranylgeranyl diphosphate synthase activity (ortholog); peptide binding (ortholog); protein farnesyltransferase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); fibroblast proliferation (ortholog); negative regulation of cell population prol iferation (ortholog); ASSOCIATED WITH anxiety disorder (ortholog); Hereditary Neoplastic Syndromes (ortholog); pheochromocytoma (ortholog); FOUND IN microtubule associated complex (inferred); protein farnesyltransferase complex (inferred) | 14 | 45568511 | 45643952 | Bonobo | 52 | symbol | gene, protein-coding, MODEL [RefSeq] |
11915819 | FNBP1 | formin binding protein 1 | ENCODES a protein that exhibits identical protein binding (inferred); lipid binding (inferred); INVOLVED IN nervous system development (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy (ortholog); dystonia (ortholog); primary coenzyme Q10 deficiency 7 (ortholog); FOUND IN cell c ortex (inferred); cytoplasm (inferred); cytoskeleton (inferred) | 9 | 101014402 | 101171302 | Bonobo | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
11965614 | FNBP4 | formin binding protein 4 | ASSOCIATED WITH agammaglobulinemia (ortholog); congenital disorder of glycosylation type IIc (ortholog); intellectual disability (ortholog); FOUND IN nucleoplasm (inferred) | 11 | 47670537 | 47722068 | Bonobo | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
11697384 | FNDC1 | fibronectin type III domain containing 1 | INVOLVED IN cellular response to hypoxia (ortholog); positive regulation of cardiac muscle cell apoptotic process (ortholog); positive regulation of protein phosphorylation (ortholog); ASSOCIATED WITH 3-methylglutaconic aciduria with deafness, encephalopathy, an d Leigh-like syndrome (ortholog); chromosome 6q24-q25 deletion syndrome (ortholog); primary ciliary dyskinesia 32 (ortholog); FOUND IN cell-cell junction (ortholog); cytoplasm (ortholog); mitochondrial membrane (ortholog) | 6 | 157057862 | 157160066 | Bonobo | 13 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
11704197 | FNDC4 | fibronectin type III domain containing 4 | INVOLVED IN negative regulation of inflammatory response (inferred); response to transforming growth factor beta (inferred); ASSOCIATED WITH lipid storage disease (ortholog); short-rib thoracic dysplasia 10 with or without polydactyly (ortholog); Tatton-Brown-Rahman syndrome (ortholog); FOUND IN end oplasmic reticulum (inferred); extracellular region (inferred); extracellular space (inferred) | 2A | 27494396 | 27497747 | Bonobo | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
11759410 | FNDC5 | fibronectin type III domain containing 5 | INVOLVED IN response to muscle activity (ortholog); ASSOCIATED WITH Cardiomegaly (ortholog); Charcot-Marie-Tooth disease dominant intermediate C (ortholog); endomyocardial fibrosis (ortholog); FOUND IN endoplasmic reticulum (ortholog) | 1 | 32152828 | 32161447 | Bonobo | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
12027790 | FNDC7 | fibronectin type III domain containing 7 | ASSOCIATED WITH autistic disorder (ortholog); hereditary spastic paraplegia 63 (ortholog) | 1 | 111085903 | 111107599 | Bonobo | 2 | symbol | gene, protein-coding, MODEL [RefSeq] |
11943909 | FNDC8 | fibronectin type III domain containing 8 | ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); Neurodevelopmental Disorders (ortholog); peroxisome biogenesis disorder 3A (ortholog); FOUND IN nucleus (inferred) | 17 | 21655487 | 21665633 | Bonobo | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
11925193 | FNDC9 | fibronectin type III domain containing 9 | ASSOCIATED WITH lymphoproliferative syndrome 1 (ortholog) | 5 | 152742642 | 152746865 | Bonobo | 2 | symbol | gene, protein-coding, MODEL [RefSeq] |
11870364 | FNIP1 | folliculin interacting protein 1 | ENCODES a protein that exhibits ATPase inhibitor activity (inferred); enzyme activator activity (inferred); enzyme binding (inferred); INVOLVED IN cellular response to nutrient levels (ortholog); lysosome organization (ortholog); negative regulation of protein localization to nucleus (ortholog); PAR TICIPATES IN mTOR signaling pathway; ASSOCIATED WITH familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); lysosomal membrane (inferred) | 5 | 127070906 | 127219548 | Bonobo | 56 | symbol | gene, protein-coding, MODEL [RefSeq] |
11883911 | FNIP2 | folliculin interacting protein 2 | ENCODES a protein that exhibits ATPase inhibitor activity (inferred); protein-folding chaperone binding (inferred); INVOLVED IN intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); negative regulation of cell population proliferation (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Leukoencephalopathies (ortholog); FOUND IN centriolar satellite (inferred); cytoplasm (inferred); cytosol (inferred) | 4 | 151086854 | 151224192 | Bonobo | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
11758565 | FN3KRP | fructosamine 3 kinase related protein | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); ASSOCIATED WITH generalized epilepsy (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred) | 17 | 77134273 | 77145543 | Bonobo | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
11942986 | FNBP1L | formin binding protein 1 like | ENCODES a protein that exhibits GTPase binding (inferred); lipid binding (inferred); INVOLVED IN autophagy (inferred); cilium assembly (inferred); clathrin-dependent endocytosis (inferred); ASSOCIATED WITH basal cell carcinoma (ortholog); FOUND IN cell cortex (inferred); cytoplasm (inferred); cytopl asmic vesicle (inferred) | 1 | 96117160 | 96223362 | Bonobo | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
12023302 | FNDC10 | fibronectin type III domain containing 10 | ASSOCIATED WITH chromosome 1p36 deletion syndrome (ortholog); congenital myasthenic syndrome 8 (ortholog); dilated cardiomyopathy 1LL (ortholog) | 1 | 359080 | 361223 | Bonobo | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
11892531 | FNDC11 | fibronectin type III domain containing 11 | ASSOCIATED WITH autosomal dominant nocturnal frontal lobe epilepsy (ortholog); autosomal recessive dyskeratosis congenita 5 (ortholog); developmental and epileptic encephalopathy (ortholog) | | | | Bonobo | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
12046820 | FNDC3A | fibronectin type III domain containing 3A | INVOLVED IN cell-cell adhesion (ortholog); fertilization (ortholog); Sertoli cell development (ortholog); ASSOCIATED WITH chromosome 13q14 deletion syndrome (ortholog); intellectual disability (ortholog); FOUND IN acrosomal vesicle (ortholog); cytoplasmic vesicle (ortholog); cytosol (ortholog) | 13 | 30119740 | 30347544 | Bonobo | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
11819705 | FNDC3B | fibronectin type III domain containing 3B | INVOLVED IN fibroblast migration (ortholog); negative regulation of osteoblast differentiation (ortholog); positive regulation of fat cell differentiation (ortholog); ASSOCIATED WITH acute promyelocytic leukemia (ortholog); Drug-Related Side Effects and Adverse Reactions (ortholog); Fanconi-Bickel s yndrome (ortholog); FOUND IN endoplasmic reticulum (ortholog) | 3 | 169047205 | 169408664 | Bonobo | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
11860878 | LAMTOR2 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); molecular adaptor activity (inferred); INVOLVED IN cellular response to amino acid stimulus (inferred); fibroblast migration (inferred); intracellular protein localization (inferred); PARTICIPATES IN mTOR signalin g pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease type 2 (ortholog); gastrointestinal stromal tumor (ortholog); immunodeficiency 42 (ortholog); FOUND IN cytoplasm (inferred); FNIP-folliculin RagC/D GAP (inferred); late endosome (inferred) | 1 | 131396937 | 131400695 | Bonobo | 46 | description | gene, protein-coding, MODEL [RefSeq] |
11972499 | LAMTOR4 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN positive regulation of TORC1 signaling (ortholog); protein localization to lysosome (ortholog); regulation of cell size (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH pleomorphic xanthoastrocytoma (ortholog); FOUND IN FNIP-folliculin RagC/D GAP (ortholog); lysosomal membrane (ortholog) | 7 | 92183617 | 92188967 | Bonobo | 24 | description | gene, protein-coding, MODEL [RefSeq] |
11967967 | LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); positive regulation of gene expression (ortholog); positive regulation of interleukin-8 production (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); Breast Neoplasms (ortholog); developmental and epileptic encephalopathy 32 (ortholog); FOUND IN cytosol (ortholog); FNIP-folliculin RagC/D GAP (ortholog); lysosomal membrane (ortholog) | 1 | 113050671 | 113057368 | Bonobo | 42 | description | gene, protein-coding, MODEL [RefSeq] |
11755745 | RRAGA | Ras related GTP binding A | ENCODES a protein that exhibits GTP binding (ortholog); INVOLVED IN autophagosome assembly (ortholog); cellular response to methionine (ortholog); cellular response to nutrient levels (ortholog); PARTICIPATES IN mTOR signaling pathway; FOUND IN cytoplasm (inferred); FN IP-folliculin RagC/D GAP (inferred); GATOR1 complex (inferred) | 9 | 18868781 | 18870356 | Bonobo | 81 | description | gene, protein-coding, MODEL [RefSeq] |
11917922 | RRAGC | Ras related GTP binding C | ENCODES a protein that exhibits enzyme-substrate adaptor activity (inferred); GDP binding (inferred); GTP binding (inferred); INVOLVED IN autophagosome assembly (ortholog); cellular response to nutrient levels (ortholog); cytoplasmic translation (ortholog); PARTICIPATES IN mTOR signaling pathway; AS SOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); follicular lymphoma (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); FNIP-folliculin RagC/D GAP (inferred) | 1 | 38110578 | 38132179 | Bonobo | 91 | description | gene, protein-coding, MODEL [RefSeq] |
11741698 | SLC38A9 | solute carrier family 38 member 9 | ENCODES a protein that exhibits amino acid transmembrane transporter activity (inferred); cholesterol binding (inferred); guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN amino acid transmembrane transport (inferred); amino acid transport (inferred); asparagine transport (inferred) ; ASSOCIATED WITH Liver Neoplasms (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN endosome (inferred); FNIP-folliculin RagC/D GAP (inferred); late endosome (inferred) | 5 | 58312101 | 58397365 | Bonobo | 41 | description | gene, protein-coding, MODEL [RefSeq] |