Efs Gene Search Result

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4 records found for search term Efs

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1319047	EFS	embryonal Fyn-associated substrate	The protein encoded by this gene is a member of the CAS (CRK-associated substrate) family of adaptor proteins which typically serve as scaffolds for the assembly of larger signaling complexes. These complexes form at the cell surface where integrin binding leads to the subsequent phosphorylation of ... (more) a CAS protein. Additional binding of SRC family kinases leads to CAS hyperphosphorylation and the creation of binding sites for CRK and other proteins that cause actin cytoskeleton reorganization. This gene plays a role in integrin-mediated cell attachment, spreading, and migration and also plays a role in both normal and malignant cellular transformation. This broadly expressed gene has been shown to play a role in neurite outgrowth and its expression in the thymus and lymphocytes is important for T cell maturation and the development of immunological self-tolerance. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2020]	14	23356406	23365172	Human	89	symbol , COSMIC , description , Human Proteome Map , old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
16561970	AL049829.2	novel transcript, antisense to EFS					Human		name	gene, lncrna
1321668	CASS4	Cas scaffold protein family member 4	Enables protein tyrosine kinase binding activity. Involved in several processes, including positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; positive regulation of protein tyrosine kinase activity; and positive regulation of substrate adhesion-dependent cell ... (more) spreading. Located in cytoplasm and focal adhesion. [provided by Alliance of Genome Resources, Jul 2025]	20	56412036	56460382	Human	70	old_gene_name	gene, protein-coding, VALIDATED [RefSeq]
1604801	EEFSEC	eukaryotic elongation factor, selenocysteine-tRNA specific	Enables GTPase activity. Involved in selenocysteine incorporation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of ribonucleoprotein complex. [provided by Alliance of Genome Resources, Jul 2025]	3	128153481	128426223	Human	164	symbol , old_gene_name , COSMIC , Human Proteome Map	gene, protein-coding, VALIDATED [RefSeq]