| 1305319 | Ttll12 | tubulin tyrosine ligase like 12 | ENCODES a protein that exhibits histone H4K20 trimethyltransferase activity (ortholog); histone H4K20me2 reader activity (ortholog); tubulin-tyrosine ligase activity (ortholog); INVOLVED IN negative regulation of type I interferon-mediated signaling pathway (ortholog); regulation of mitotic cell cyc le (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 4-amino-2,6-dinitrotoluene; alpha-Zearalanol | 7 | 116612609 | 116631244 | Rat | 115 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1313277 | Ttll12 | tubulin tyrosine ligase-like family, member 12 | Predicted to enable histone H4K20me3 reader activity and tubulin binding activity. Predicted to be involved in negative regulation of type I interferon-mediated signaling pathway and regulation of mitotic cell cycle. Predicted to be located in cytosol and plasma membrane. Predicted to be active in c ytoplasm. Is expressed in liver; medulla oblongata basal plate mantle layer; metanephros; submandibular gland primordium; and thymus primordium. Orthologous to human TTLL12 (tubulin tyrosine ligase like 12). [provided by Alliance of Genome Resources, Apr 2025] | 15 | 83459295 | 83479358 | Mouse | 129 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1604381 | TTLL12 | tubulin tyrosine ligase like 12 | Enables histone H4K20me3 reader activity and tubulin binding activity. Involved in negative regulation of type I interferon-mediated signaling pathway and regulation of mitotic cell cycle. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025] | 22 | 43166622 | 43187134 | Human | 121 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8890738 | Ttll12 | tubulin tyrosine ligase like 12 | ENCODES a protein that exhibits histone H4K20 trimethyltransferase activity (ortholog); histone H4K20me2 reader activity (ortholog); tubulin-tyrosine ligase activity (ortholog); INVOLVED IN negative regulation of type I interferon-mediated signaling pathway (ortholog); regulation of mitotic cell cyc le (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog) | NW_004955413 | 28316936 | 28333423 | Chinchilla | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11965944 | TTLL12 | tubulin tyrosine ligase like 12 | ENCODES a protein that exhibits histone H4K20 trimethyltransferase activity (ortholog); tubulin-tyrosine ligase activity (ortholog); INVOLVED IN chromatin organization (inferred); negative regulation of type I interferon-mediated signaling pathway (inferred); regulation of mitotic cell cycle (inferr ed); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred) | 22 | 24038128 | 24070135 | Bonobo | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12379637 | TTLL12 | tubulin tyrosine ligase like 12 | ENCODES a protein that exhibits histone H4K20 trimethyltransferase activity (ortholog); tubulin-tyrosine ligase activity (ortholog); INVOLVED IN chromatin organization (inferred); negative regulation of type I interferon-mediated signaling pathway (inferred); regulation of mitotic cell cycle (inferr ed); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred) | 10 | 22367590 | 22385167 | Dog | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12610789 | Ttll12 | tubulin tyrosine ligase like 12 | ENCODES a protein that exhibits histone H4K20 trimethyltransferase activity (ortholog); tubulin-tyrosine ligase activity (ortholog); INVOLVED IN chromatin organization (inferred); negative regulation of type I interferon-mediated signaling pathway (inferred); regulation of mitotic cell cycle (inferr ed); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred) | NW_004936718 | 996758 | 1013372 | Squirrel | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14388682 | TTLL12 | | | | | | Fly | | symbol | gene, null |
| 625838491 | Ttll12 | tubulin tyrosine ligase like 12 | ENCODES a protein that exhibits histone H4K20 trimethyltransferase activity (ortholog); histone H4K20me2 reader activity (ortholog); tubulin-tyrosine ligase activity (ortholog); INVOLVED IN negative regulation of type I interferon-mediated signaling pathway (ortholog); regulation of mitotic cell cyc le (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog) | | | | Black Rat | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18931280 | Ttll12 | tubulin tyrosine ligase like 12 | ENCODES a protein that exhibits histone H4K20 trimethyltransferase activity (ortholog); tubulin-tyrosine ligase activity (ortholog); INVOLVED IN chromatin organization (inferred); negative regulation of type I interferon-mediated signaling pathway (inferred); regulation of mitotic cell cycle (inferr ed); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred) | | | | Naked Mole-Rat | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18690956 | TTLL12 | tubulin tyrosine ligase like 12 | ENCODES a protein that exhibits histone H4K20 trimethyltransferase activity (ortholog); tubulin-tyrosine ligase activity (ortholog); INVOLVED IN chromatin organization (inferred); negative regulation of type I interferon-mediated signaling pathway (inferred); regulation of mitotic cell cycle (inferr ed); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred) | | | | Green Monkey | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155257305 | ttll12 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 13905625 | TTLL12 | tubulin tyrosine ligase like 12 | ENCODES a protein that exhibits histone H4K20 trimethyltransferase activity (ortholog); tubulin-tyrosine ligase activity (ortholog); INVOLVED IN chromatin organization (inferred); negative regulation of type I interferon-mediated signaling pathway (inferred); regulation of mitotic cell cycle (inferr ed); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred) | | | | Pig | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155257304 | ttll12.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 16565859 | AC113403.1 | tubulin tyrosine ligase-like family, member 12 (TTLL12) pseudogene | | | | | Human | | name | gene, processed_pseudogene |