| 1306756 | Tbcc | tubulin folding cofactor C | ENCODES a protein that exhibits GTPase activator activity (ortholog); GTPase activity (ortholog); INVOLVED IN post-chaperonin tubulin folding pathway (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); photoreceptor connecting cilium (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodi oxine; amphetamine; bisphenol A | 9 | 21596472 | 21597660 | Rat | 79 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1315555 | TBCC | tubulin folding cofactor C | Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. [provided by RefSeq, Jul 2008] | 6 | 42744498 | 42746103 | Human | 79 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1315556 | Tbcc | tubulin-specific chaperone C | Predicted to enable GTPase activity. Predicted to be involved in post-chaperonin tubulin folding pathway and tubulin complex assembly. Predicted to be located in cytosol and photoreceptor connecting cilium. Predicted to be active in cytoplasm. Is expressed in Meckel's cartilage; autopod; and skeleto n. Orthologous to human TBCC (tubulin folding cofactor C). [provided by Alliance of Genome Resources, Apr 2025] | 17 | 47201547 | 47203389 | Mouse | 84 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8842722 | Tbcc | tubulin folding cofactor C | ENCODES a protein that exhibits GTPase activity (ortholog); INVOLVED IN post-chaperonin tubulin folding pathway (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); photoreceptor connecting cilium (ortholog) | NW_004955437 | 8808021 | 8809598 | Chinchilla | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11745490 | TBCC | tubulin folding cofactor C | ENCODES a protein that exhibits GTPase activator activity (inferred); GTPase activity (inferred); tubulin binding (inferred); INVOLVED IN post-chaperonin tubulin folding pathway (inferred); protein folding (inferred); tubulin complex assembly (inferred); FOUND IN cytoplasm (inferred); cytosol (infer red); photoreceptor connecting cilium (inferred) | 6 | 42334902 | 42336560 | Bonobo | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12383724 | TBCC | tubulin folding cofactor C | ENCODES a protein that exhibits GTPase activator activity (inferred); GTPase activity (inferred); tubulin binding (inferred); INVOLVED IN post-chaperonin tubulin folding pathway (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); photoreceptor connecting cilium (inferred) | 12 | 11332736 | 11334799 | Dog | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12447170 | Tbcc | tubulin folding cofactor C | ENCODES a protein that exhibits GTPase activator activity (inferred); GTPase activity (inferred); tubulin binding (inferred); INVOLVED IN post-chaperonin tubulin folding pathway (inferred); protein folding (inferred); tubulin complex assembly (inferred); FOUND IN cytoplasm (inferred); cytosol (infer red); photoreceptor connecting cilium (inferred) | NW_004936476 | 17145956 | 17147299 | Squirrel | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14006822 | TBCC | tubulin folding cofactor C | ENCODES a protein that exhibits GTPase activator activity (inferred); GTPase activity (inferred); tubulin binding (inferred); INVOLVED IN post-chaperonin tubulin folding pathway (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); photoreceptor connecting cilium (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 15 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 14388671 | TBCC | | | | | | Fly | | symbol | gene, null |
| 18408501 | TBCC | tubulin folding cofactor C | ENCODES a protein that exhibits GTPase activity (ortholog); INVOLVED IN post-chaperonin tubulin folding pathway (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); photoreceptor connecting cilium (ortholog) | | | | Green Monkey | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18935615 | Tbcc | tubulin folding cofactor C | ENCODES a protein that exhibits GTPase activator activity (inferred); GTPase activity (inferred); tubulin binding (inferred); INVOLVED IN post-chaperonin tubulin folding pathway (inferred); protein folding (inferred); tubulin complex assembly (inferred); FOUND IN cytoplasm (inferred); cytosol (infer red); photoreceptor connecting cilium (inferred) | | | | Naked Mole-Rat | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155246232 | tbcc | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625898325 | Tbcc | tubulin folding cofactor C | ENCODES a protein that exhibits GTPase activity (ortholog); INVOLVED IN post-chaperonin tubulin folding pathway (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); photoreceptor connecting cilium (ortholog) | | | | Black Rat | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14388672 | tbcc-1 | | | | | | Roundworm | | symbol | gene, null |
| 155239533 | tbcc.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 1309604 | Tbccd1 | TBCC domain containing 1 | INVOLVED IN maintenance of centrosome location (ortholog); maintenance of Golgi location (ortholog); regulation of cell migration (ortholog); FOUND IN spindle pole centrosome (ortholog); INTERACTS WITH 1,3-dinitrobenzene; acrylamide; bis(2-ethylhexyl) phthalate | 11 | 91672948 | 91710120 | Rat | 63 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1605661 | TBCCD1 | TBCC domain containing 1 | Involved in several processes, including maintenance of Golgi location; maintenance of centrosome location; and regulation of cell shape. Located in spindle pole centrosome. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 186546067 | 186570543 | Human | 53 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1621512 | Tbccd1 | TBCC domain containing 1 | Predicted to be involved in several processes, including maintenance of Golgi location; maintenance of centrosome location; and regulation of cell shape. Predicted to be located in cytoplasm. Predicted to be active in spindle pole centrosome. Is expressed in liver; pancreas; and retina. Orthologous to human TBCCD1 (TBCC domain containing 1). [provided by Alliance of Genome Resources, Apr 2025] | 16 | 22631964 | 22676441 | Mouse | 68 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8932198 | Tbccd1 | TBCC domain containing 1 | INVOLVED IN maintenance of centrosome location (ortholog); maintenance of Golgi location (ortholog); regulation of cell migration (ortholog); FOUND IN spindle pole centrosome (ortholog) | NW_004955420 | 21113527 | 21135704 | Chinchilla | 6 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11871988 | TBCCD1 | TBCC domain containing 1 | INVOLVED IN maintenance of centrosome location (inferred); maintenance of Golgi location (inferred); regulation of cell migration (inferred); FOUND IN centrosome (inferred); spindle pole (inferred); spindle pole centrosome (inferred) | 3 | 183577248 | 183601761 | Bonobo | 11 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12234026 | TBCCD1 | TBCC domain containing 1 | INVOLVED IN maintenance of centrosome location (inferred); maintenance of Golgi location (inferred); regulation of cell migration (inferred); FOUND IN centrosome (inferred); spindle pole (inferred); spindle pole centrosome (inferred) | 34 | 19165290 | 19185020 | Dog | 8 | symbol , old_gene_name , name | gene, protein-coding |
| 12691720 | Tbccd1 | TBCC domain containing 1 | INVOLVED IN maintenance of centrosome location (inferred); maintenance of Golgi location (inferred); regulation of cell migration (inferred); FOUND IN centrosome (inferred); spindle pole (inferred); spindle pole centrosome (inferred) | NW_004936578 | 3374826 | 3404462 | Squirrel | 11 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14190911 | TBCCD1 | TBCC domain containing 1 | INVOLVED IN maintenance of centrosome location (inferred); maintenance of Golgi location (inferred); regulation of cell migration (inferred); FOUND IN centrosome (inferred); spindle pole (inferred); spindle pole centrosome (inferred) | | | | Pig | 11 | symbol , old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 18712836 | TBCCD1 | TBCC domain containing 1 | INVOLVED IN maintenance of centrosome location (inferred); maintenance of Golgi location (inferred); regulation of cell migration (inferred); FOUND IN centrosome (inferred); spindle pole (inferred); spindle pole centrosome (inferred) | | | | Green Monkey | 11 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18911256 | Tbccd1 | TBCC domain containing 1 | INVOLVED IN regulation of cell migration (ortholog); regulation of cell shape (ortholog); FOUND IN centrosome (inferred); spindle pole (inferred); spindle pole centrosome (inferred) | | | | Naked Mole-Rat | 8 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 150657785 | TBCCD1 | TBCC domain containing 1 | INVOLVED IN maintenance of centrosome location (inferred); maintenance of Golgi location (inferred); regulation of cell migration (inferred); FOUND IN centrosome (inferred); spindle pole (inferred); spindle pole centrosome (inferred) | | | | Dog | 10 | symbol , name | gene, protein-coding |
| 625955336 | Tbccd1 | TBCC domain containing 1 | INVOLVED IN maintenance of centrosome location (ortholog); maintenance of Golgi location (ortholog); regulation of cell migration (ortholog); FOUND IN spindle pole centrosome (ortholog) | | | | Black Rat | 6 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 38605114 | LOC100128676 | TBCC domain containing 1 pseudogene | | 12 | 56378831 | 56382831 | Human | | name | gene, pseudo, INFERRED [RefSeq] |
| 12714869 | LOC101972775 | TBCC domain-containing protein 1-like | | NW_004936536 | 5590621 | 5592313 | Squirrel | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 18575638 | LOC103238527 | TBCC domain-containing protein 1-like | | | | | Green Monkey | | name | gene, pseudo, MODEL [RefSeq] |
| 11815602 | LOC103787163 | TBCC domain-containing protein 1-like | | 12 | 32529287 | 32533111 | Bonobo | | name | gene, pseudo, MODEL [RefSeq] |
| 16562017 | AC025574.1 | TBCC domain containing 1 (TBCCD1) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 155256062 | tbccd1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155259823 | tbccd1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 1345059 | RP2 | RP2 activator of ARL3 GTPase | The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly- folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death [provided by RefSeq, Jul 2008] | X | 46837043 | 46882358 | Human | 357 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |