| 1305658 | Taf1c | TATA-box binding protein associated factor, RNA polymerase 1 subunit C | ENCODES a protein that exhibits RNA polymerase I core promoter sequence-specific DNA binding (ortholog); RNA polymerase I general transcription initiation factor activity (ortholog); INVOLVED IN regulation of DNA-templated transcription (ortholog); PARTICIPATES IN RNA polymerase I transcription path way; ASSOCIATED WITH autistic disorder (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN fibrillar center (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 19 | 64561079 | 64567599 | Rat | 89 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1313816 | TAF1C | TATA-box binding protein associated factor, RNA polymerase I subunit C | Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymera se properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2011] | 16 | 84177855 | 84187057 | Human | 86 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1313817 | Taf1c | TATA-box binding protein associated factor, RNA polymerase I, C | Predicted to enable RNA polymerase I core promoter sequence-specific DNA binding activity and RNA polymerase I general transcription initiation factor activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly. Predicted to act upstream of or within transcription by RNA po lymerase I. Part of RNA polymerase transcription factor SL1 complex. Is expressed in limb and limb mesenchyme. Orthologous to human TAF1C (TATA-box binding protein associated factor, RNA polymerase I subunit C). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 120324713 | 120331945 | Mouse | 93 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8871473 | Taf1c | TATA-box binding protein associated factor, RNA polymerase I subunit C | ENCODES a protein that exhibits RNA polymerase I core promoter sequence-specific DNA binding (ortholog); RNA polymerase I general transcription initiation factor activity (ortholog); INVOLVED IN regulation of DNA-templated transcription (ortholog); PARTICIPATES IN RNA polymerase I transcription path way; ASSOCIATED WITH autistic disorder (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN fibrillar center (ortholog); nucleolus (ortholog); nucleoplasm (ortholog) | NW_004955564 | 121988 | 132347 | Chinchilla | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11754113 | TAF1C | TATA-box binding protein associated factor, RNA polymerase I subunit C | ENCODES a protein that exhibits RNA polymerase I core promoter sequence-specific DNA binding (inferred); RNA polymerase I general transcription initiation factor activity (inferred); INVOLVED IN regulation of DNA-templated transcription (inferred); RNA polymerase I preinitiation complex assembly (in ferred); transcription by RNA polymerase I (inferred); PARTICIPATES IN RNA polymerase I transcription pathway; ASSOCIATED WITH autistic disorder (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN fibrillar center (inferred); nucleolus (inferred); nucleoplasm (inferred) | 16 | 64843197 | 64852408 | Bonobo | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12129910 | TAF1C | TATA-box binding protein associated factor, RNA polymerase I subunit C | ENCODES a protein that exhibits RNA polymerase I general transcription initiation factor activity (ortholog); INVOLVED IN regulation of DNA-templated transcription (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; ASSOCIATED WITH autistic disorder (ortholog); developmental and epil eptic encephalopathy 11 (ortholog); FOUND IN fibrillar center (ortholog); nucleolus (ortholog); nucleoplasm (ortholog) | 5 | 68175196 | 68184267 | Dog | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12517208 | Taf1c | TATA-box binding protein associated factor, RNA polymerase I subunit C | ENCODES a protein that exhibits RNA polymerase I core promoter sequence-specific DNA binding (ortholog); RNA polymerase I general transcription initiation factor activity (ortholog); INVOLVED IN regulation of DNA-templated transcription (ortholog); PARTICIPATES IN RNA polymerase I transcription path way; ASSOCIATED WITH autistic disorder (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN fibrillar center (ortholog); nucleolus (ortholog); nucleoplasm (ortholog) | NW_004936641 | 3649177 | 3653798 | Squirrel | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625921784 | Taf1c | TATA-box binding protein associated factor, RNA polymerase I subunit C | ENCODES a protein that exhibits RNA polymerase I core promoter sequence-specific DNA binding (ortholog); RNA polymerase I general transcription initiation factor activity (ortholog); INVOLVED IN regulation of DNA-templated transcription (ortholog); PARTICIPATES IN RNA polymerase I transcription path way; ASSOCIATED WITH autistic disorder (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN fibrillar center (ortholog); nucleolus (ortholog); nucleoplasm (ortholog) | | | | Black Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626171564 | taf1c | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626175195 | taf1c | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 13900818 | TAF1C | TATA-box binding protein associated factor, RNA polymerase I subunit C | ENCODES a protein that exhibits RNA polymerase I core promoter sequence-specific DNA binding (inferred); RNA polymerase I general transcription initiation factor activity (inferred); INVOLVED IN regulation of DNA-templated transcription (inferred); RNA polymerase I preinitiation complex assembly (in ferred); transcription by RNA polymerase I (inferred); PARTICIPATES IN RNA polymerase I transcription pathway; ASSOCIATED WITH autistic disorder (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN fibrillar center (inferred); nucleolus (inferred); nucleoplasm (inferred) | | | | Pig | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18905501 | Taf1c | TATA-box binding protein associated factor, RNA polymerase I subunit C | ENCODES a protein that exhibits RNA polymerase I general transcription initiation factor activity (ortholog); INVOLVED IN regulation of DNA-templated transcription (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; ASSOCIATED WITH autistic disorder (ortholog); developmental and epil eptic encephalopathy 11 (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); RNA polymerase transcription factor SL1 complex (ortholog) | | | | Naked Mole-Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18365169 | TAF1C | TATA-box binding protein associated factor, RNA polymerase I subunit C | ENCODES a protein that exhibits RNA polymerase I core promoter sequence-specific DNA binding (inferred); RNA polymerase I general transcription initiation factor activity (inferred); INVOLVED IN regulation of DNA-templated transcription (inferred); RNA polymerase I preinitiation complex assembly (in ferred); transcription by RNA polymerase I (inferred); PARTICIPATES IN RNA polymerase I transcription pathway; ASSOCIATED WITH autistic disorder (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN fibrillar center (inferred); nucleolus (inferred); nucleoplasm (inferred) | | | | Green Monkey | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1601854 | TAF1D | TATA-box binding protein associated factor, RNA polymerase I subunit D | TAF1D is a member of the SL1 complex, which includes TBP (MIM 600075) and TAF1A (MIM 604903), TAF1B (MIM 604904), and TAF1C (MIM 604905), and plays a role in RNA polymerase I transcription (Wang et al., 2004 [PubMed 15520167]; Gorski et al., 2007 [PubMed 1731817 7]).[supplied by OMIM, Jun 2009] | 11 | 93730194 | 93741495 | Human | 155 | description | gene, protein-coding, VALIDATED [RefSeq] |