| 61899 | Slc29a1 | solute carrier family 29 member 1 | ENCODES a protein that exhibits nucleoside transmembrane transporter activity; uridine transmembrane transporter activity; adenine transmembrane transporter activity (ortholog); INVOLVED IN cellular response to glucose stimulus; cellular response to hypoxia; excitatory postsynaptic potential; PARTIC IPATES IN azathioprine pharmacodynamics pathway; gemcitabine pharmacodynamics pathway; gemcitabine pharmacokinetics pathway; ASSOCIATED WITH alcohol dependence; brain ischemia; Experimental Diabetes Mellitus; FOUND IN basolateral plasma membrane; postsynapse; presynapse; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 9 | 22897099 | 22911640 | Rat | 357 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 62192 | Slc29a1 | solute carrier family 29 (nucleoside transporters), member 1 | Enables neurotransmitter transmembrane transporter activity; purine nucleoside transmembrane transporter activity; and uridine transmembrane transporter activity. Involved in neurotransmitter uptake and nucleoside transport. Acts upstream of or within ADP catabolic process; AMP catabolic process; an d nucleoside transport. Is active in plasma membrane. Is expressed in several structures, including central nervous system; hemolymphoid system; hindlimb phalanx; liver; and skeletal musculature. Used to study alcohol dependence and diffuse idiopathic skeletal hyperostosis. Orthologous to human SLC29A1 (solute carrier family 29 member 1 (Augustine blood group)). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 45896126 | 45910544 | Mouse | 389 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 737565 | SLC29A1 | solute carrier family 29 member 1 (Augustine blood group) | This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008] | 6 | 44219615 | 44234142 | Human | 322 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 9035468 | Slc29a1 | solute carrier family 29 member 1 (Augustine blood group) | ENCODES a protein that exhibits adenine transmembrane transporter activity (ortholog); cytidine transmembrane transporter activity (ortholog); guanine transmembrane transporter activity (ortholog); INVOLVED IN adenine transport (ortholog); adenosine transport (ortholog); cellular response to glucose stimulus (ortholog); PARTICIPATES IN azathioprine pharmacodynamics pathway; gemcitabine pharmacodynamics pathway; gemcitabine pharmacokinetics pathway; ASSOCIATED WITH alcohol dependence (ortholog); Alcohol Withdrawal Seizures (ortholog); Animal Disease Models (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); plasma membrane (ortholog) | NW_004955437 | 9850279 | 9862412 | Chinchilla | 80 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11884873 | SLC29A1 | solute carrier family 29 member 1 (Augustine blood group) | ENCODES a protein that exhibits nucleoside transmembrane transporter activity (ortholog); INVOLVED IN cellular response to glucose stimulus (ortholog); cellular response to hypoxia (ortholog); excitatory postsynaptic potential (ortholog); PARTICIPATES IN azathioprine pharmacodynamics pathway; gemcit abine pharmacodynamics pathway; gemcitabine pharmacokinetics pathway; ASSOCIATED WITH alcohol dependence (ortholog); Alcohol Withdrawal Seizures (ortholog); Animal Disease Models (ortholog); FOUND IN postsynapse (ortholog); presynapse (ortholog) | 6 | 43815006 | 43830290 | Bonobo | 68 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12334861 | SLC29A1 | solute carrier family 29 member 1 | ENCODES a protein that exhibits nucleoside transmembrane transporter activity (ortholog); INVOLVED IN cellular response to glucose stimulus (ortholog); cellular response to hypoxia (ortholog); excitatory postsynaptic potential (ortholog); PARTICIPATES IN azathioprine pharmacodynamics pathway; gemcit abine pharmacodynamics pathway; gemcitabine pharmacokinetics pathway; ASSOCIATED WITH alcohol dependence (ortholog); Alcohol Withdrawal Seizures (ortholog); Animal Disease Models (ortholog); FOUND IN postsynapse (ortholog); presynapse (ortholog) | 12 | 12632233 | 12644669 | Dog | 69 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12532886 | Slc29a1 | solute carrier family 29 member 1 (Augustine blood group) | ENCODES a protein that exhibits nucleoside transmembrane transporter activity (ortholog); INVOLVED IN cellular response to glucose stimulus (ortholog); cellular response to hypoxia (ortholog); excitatory postsynaptic potential (ortholog); PARTICIPATES IN azathioprine pharmacodynamics pathway; gemcit abine pharmacodynamics pathway; gemcitabine pharmacokinetics pathway; ASSOCIATED WITH alcohol dependence (ortholog); Alcohol Withdrawal Seizures (ortholog); Animal Disease Models (ortholog); FOUND IN plasma membrane (ortholog); postsynapse (ortholog); presynapse (ortholog) | NW_004936476 | 15849054 | 15862486 | Squirrel | 67 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13851842 | SLC29A1 | solute carrier family 29 member 1 | ENCODES a protein that exhibits nucleoside transmembrane transporter activity (ortholog); INVOLVED IN cellular response to glucose stimulus (ortholog); cellular response to hypoxia (ortholog); excitatory postsynaptic potential (ortholog); PARTICIPATES IN azathioprine pharmacodynamics pathway; gemcit abine pharmacodynamics pathway; gemcitabine pharmacokinetics pathway; ASSOCIATED WITH alcohol dependence (ortholog); Alcohol Withdrawal Seizures (ortholog); Animal Disease Models (ortholog); FOUND IN postsynapse (ortholog); presynapse (ortholog) | | | | Pig | 72 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18514890 | SLC29A1 | solute carrier family 29 member 1 (Augustine blood group) | ENCODES a protein that exhibits nucleoside transmembrane transporter activity (ortholog); INVOLVED IN cellular response to glucose stimulus (ortholog); cellular response to hypoxia (ortholog); excitatory postsynaptic potential (ortholog); PARTICIPATES IN azathioprine pharmacodynamics pathway; gemcit abine pharmacodynamics pathway; gemcitabine pharmacokinetics pathway; ASSOCIATED WITH alcohol dependence (ortholog); Alcohol Withdrawal Seizures (ortholog); Animal Disease Models (ortholog); FOUND IN postsynapse (ortholog); presynapse (ortholog) | | | | Green Monkey | 68 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18928196 | Slc29a1 | solute carrier family 29 member 1 (Augustine blood group) | ENCODES a protein that exhibits adenine transmembrane transporter activity (ortholog); cytidine transmembrane transporter activity (ortholog); guanine transmembrane transporter activity (ortholog); INVOLVED IN adenine transport (ortholog); adenosine transport (ortholog); cellular response to glucose stimulus (ortholog); PARTICIPATES IN azathioprine pharmacodynamics pathway; gemcitabine pharmacodynamics pathway; gemcitabine pharmacokinetics pathway; ASSOCIATED WITH alcohol dependence (ortholog); Alcohol Withdrawal Seizures (ortholog); Animal Disease Models (ortholog); FOUND IN plasma membrane (ortholog); postsynapse (ortholog); presynapse (ortholog) | | | | Naked Mole-Rat | 70 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 285467809 | slc29a1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626055709 | Slc29a1 | solute carrier family 29 member 1 (Augustine blood group) | ENCODES a protein that exhibits adenine transmembrane transporter activity (ortholog); cytidine transmembrane transporter activity (ortholog); guanine transmembrane transporter activity (ortholog); INVOLVED IN adenine transport (ortholog); adenosine transport (ortholog); cellular response to glucose stimulus (ortholog); PARTICIPATES IN azathioprine pharmacodynamics pathway; gemcitabine pharmacodynamics pathway; gemcitabine pharmacokinetics pathway; ASSOCIATED WITH alcohol dependence (ortholog); Alcohol Withdrawal Seizures (ortholog); Animal Disease Models (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); plasma membrane (ortholog) | | | | Black Rat | 80 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 287893090 | slc29a1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 285467551 | slc29a1.S | | | | | | African Clawed Frog | | symbol | gene, null |