Nfkb2 Gene Search Result

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18 records found for search term Nfkb2

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1307189	Nfkb2	nuclear factor kappa B subunit 2	ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN response to cytokine; response to l ... (more) ipopolysaccharide; canonical NF-kappaB signal transduction (ortholog); PARTICIPATES IN adenosine signaling pathway; interleukin-12 signaling pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH Cerebral Hemorrhage; Experimental Diabetes Mellitus; Parkinsonism; FOUND IN Bcl3/NF-kappaB2 complex (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 1-naphthyl isothiocyanate	1	255106010	255114649	Rat	301	symbol , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
1316230	NFKB2	nuclear factor kappa B subunit 2	This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a tran ... (more) scriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]	10	102394110	102402529	Human	399	symbol , old_gene_name , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1316231	Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100	Enables DNA-binding transcription factor activity. Involved in non-canonical NF-kappaB signal transduction. Acts upstream of or within several processes, including follicular dendritic cell differentiation; germinal center formation; and spleen development. Located in nucleus. Is expressed in severa ... (more) l structures, including central nervous system; early conceptus; genitourinary system; musculature; and thymus primordium. Used to study common variable immunodeficiency. Human ortholog(s) of this gene implicated in common variable immunodeficiency 10. Orthologous to human NFKB2 (nuclear factor kappa B subunit 2). [provided by Alliance of Genome Resources, Jul 2025]	19	46285478	46300839	Mouse	510	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
8720526	Nfkb2	nuclear factor kappa B subunit 2	ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN canonical NF-kappaB signal transduc ... (more) tion (ortholog); extracellular matrix organization (ortholog); follicular dendritic cell differentiation (ortholog); PARTICIPATES IN adenosine signaling pathway; interleukin-12 signaling pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH atrophic gastritis (ortholog); Cerebral Hemorrhage (ortholog); common variable immunodeficiency (ortholog); FOUND IN Bcl3/NF-kappaB2 complex (ortholog); cytoplasm (ortholog); cytosol (ortholog)	NW_004955485	7994730	8001776	Chinchilla	57	symbol	gene, protein-coding, MODEL [RefSeq]
11841393	NFKB2	nuclear factor kappa B subunit 2	ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN extracellular matrix organization (ortholog); follicular dendritic cell differentiation (orth ... (more) olog); germinal center formation (ortholog); PARTICIPATES IN adenosine signaling pathway; interleukin-12 signaling pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH atrophic gastritis (ortholog); Cerebral Hemorrhage (ortholog); common variable immunodeficiency (ortholog); FOUND IN NF-kappaB complex (ortholog)	10	98997604	99006407	Bonobo	74	symbol	gene, protein-coding, MODEL [RefSeq]
12174258	NFKB2	nuclear factor kappa B subunit 2	ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN extracellular matrix organization (ortholog); follicular dendritic cell differentiation (orth ... (more) olog); germinal center formation (ortholog); PARTICIPATES IN adenosine signaling pathway; interleukin-12 signaling pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH atrophic gastritis (ortholog); Cerebral Hemorrhage (ortholog); common variable immunodeficiency (ortholog); FOUND IN NF-kappaB complex (ortholog)	28	14902212	14910437	Dog	71	symbol	gene, protein-coding, MODEL [RefSeq]
12699203	Nfkb2	nuclear factor kappa B subunit 2	ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN extracellular matrix organization (ortholog); follicular dendritic cell differentiation (orth ... (more) olog); germinal center formation (ortholog); PARTICIPATES IN adenosine signaling pathway; interleukin-12 signaling pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH atrophic gastritis (ortholog); Cerebral Hemorrhage (ortholog); common variable immunodeficiency (ortholog); FOUND IN NF-kappaB complex (ortholog)	NW_004936600	3465016	3471258	Squirrel	71	symbol	gene, protein-coding, MODEL [RefSeq]
18917568	Nfkb2	nuclear factor kappa B subunit 2	ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN canonical NF-kappaB signal transduction (ortholog); extracellular matrix organization (ortholog); follicular dend ... (more) ritic cell differentiation (ortholog); PARTICIPATES IN adenosine signaling pathway; interleukin-12 signaling pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH atrophic gastritis (ortholog); Cerebral Hemorrhage (ortholog); common variable immunodeficiency (ortholog); FOUND IN Bcl3/NF-kappaB2 complex (ortholog); cytosol (ortholog); NF-kappaB complex (ortholog)				Naked Mole-Rat	67	symbol	gene, protein-coding, MODEL [RefSeq]
625918136	Nfkb2	nuclear factor kappa B subunit 2	ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN canonical NF-kappaB signal transduc ... (more) tion (ortholog); extracellular matrix organization (ortholog); follicular dendritic cell differentiation (ortholog); PARTICIPATES IN adenosine signaling pathway; interleukin-12 signaling pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH atrophic gastritis (ortholog); Cerebral Hemorrhage (ortholog); common variable immunodeficiency (ortholog); FOUND IN Bcl3/NF-kappaB2 complex (ortholog); cytoplasm (ortholog); cytosol (ortholog)				Black Rat	57	symbol	gene, protein-coding, MODEL [RefSeq]
155232740	nfkb2						Tropical Clawed Frog		symbol	gene, null
18338834	NFKB2	nuclear factor kappa B subunit 2	ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN extracellular matrix organization (ortholog); follicular dendritic cell differentiation (orth ... (more) olog); germinal center formation (ortholog); PARTICIPATES IN adenosine signaling pathway; interleukin-12 signaling pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH atrophic gastritis (ortholog); Cerebral Hemorrhage (ortholog); common variable immunodeficiency (ortholog); FOUND IN NF-kappaB complex (ortholog)				Green Monkey	73	symbol	gene, protein-coding, MODEL [RefSeq]
14093549	NFKB2	nuclear factor kappa B subunit 2	ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN extracellular matrix organization (ortholog); follicular dendritic cell differentiation (orth ... (more) olog); germinal center formation (ortholog); PARTICIPATES IN adenosine signaling pathway; interleukin-12 signaling pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH atrophic gastritis (ortholog); Cerebral Hemorrhage (ortholog); common variable immunodeficiency (ortholog); FOUND IN NF-kappaB complex (ortholog); INTERACTS WITH deoxynivalenol				Pig	72	symbol , old_gene_symbol	gene, protein-coding, MODEL [RefSeq]
155232739	nfkb2.L						African Clawed Frog		symbol	gene, null
155255922	nfkb2.S						African Clawed Frog		symbol	gene, null
1589647	Nfkb2-ps1	nuclear factor kappa B subunit 2, pseudogene 1		3	160425340	160428728	Rat		symbol , PhenoGen	gene, pseudo, MODEL [RefSeq]
16564600	AP001017.1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (NFKB2) pseudogene					Human		name	gene, processed_pseudogene
16564665	AP002414.3	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (NFKB2) pseudogene		18	12091518	12093086	Human		name	gene, pseudo, INFERRED [RefSeq]
1352761	RELA	RELA proto-oncogene, NF-kB subunit	NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed ... (more) of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]	11	65653601	65663857	Human	3120	description	gene, protein-coding, REVIEWED [RefSeq]