| 708367 | Hsd17b12 | hydroxysteroid (17-beta) dehydrogenase 12 | ENCODES a protein that exhibits collagen binding (ortholog); fibronectin binding (ortholog); heparin binding (ortholog); INVOLVED IN extracellular matrix organization (ortholog); fatty acid elongation, saturated fatty acid (ortholog); positive regulation of cell-substrate adhesion (ortholog); PARTIC IPATES IN steroid hormone biosynthetic pathway; unsaturated fatty acid biosynthetic pathway; FOUND IN extracellular matrix (ortholog); fatty acid elongase complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 100445393 | 100568898 | Rat | 148 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 734129 | Hsd17b12 | hydroxysteroid (17-beta) dehydrogenase 12 | Enables collagen binding activity; fibronectin binding activity; and heparin binding activity. Acts upstream of or within extracellular matrix organization and positive regulation of cell-substrate adhesion. Located in extracellular matrix. Is expressed in several structures, including alimentary sy stem; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 93863042 | 93988254 | Mouse | 156 | symbol , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1346748 | HSD17B12 | hydroxysteroid 17-beta dehydrogenase 12 | This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. [provided by RefSeq, Oct 2011] | 11 | 43556721 | 43856615 | Human | 147 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8878359 | Hsd17b12 | hydroxysteroid 17-beta dehydrogenase 12 | ENCODES a protein that exhibits collagen binding (ortholog); fibronectin binding (ortholog); heparin binding (ortholog); INVOLVED IN extracellular matrix organization (ortholog); fatty acid elongation, saturated fatty acid (ortholog); positive regulation of cell-substrate adhesion (ortholog); FOUND IN extracellular matrix (ortholog); fatty acid elongase complex (ortholog) | NW_004955422 | 3721452 | 3864801 | Chinchilla | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11980468 | HSD17B12 | hydroxysteroid 17-beta dehydrogenase 12 | ENCODES a protein that exhibits collagen binding (inferred); estradiol 17-beta-dehydrogenase [NAD(P)+] activity (inferred); fibronectin binding (inferred); INVOLVED IN extracellular matrix organization (ortholog); positive regulation of cell-substrate adhesion (ortholog); FOUND IN endoplasmic reticu lum (inferred); endoplasmic reticulum membrane (inferred); extracellular matrix (inferred) | 11 | 43641323 | 43817214 | Bonobo | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12133258 | HSD17B12 | hydroxysteroid 17-beta dehydrogenase 12 | ENCODES a protein that exhibits collagen binding (ortholog); fibronectin binding (ortholog); heparin binding (ortholog); INVOLVED IN extracellular matrix organization (ortholog); positive regulation of cell-substrate adhesion (ortholog); FOUND IN extracellular matrix (ortholog) | 18 | 25907366 | 26061643 | Dog | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12722381 | Hsd17b12 | hydroxysteroid 17-beta dehydrogenase 12 | ENCODES a protein that exhibits collagen binding (inferred); estradiol 17-beta-dehydrogenase [NAD(P)+] activity (inferred); fibronectin binding (inferred); INVOLVED IN extracellular matrix organization (ortholog); positive regulation of cell-substrate adhesion (ortholog); FOUND IN endoplasmic reticu lum (inferred); endoplasmic reticulum membrane (inferred); extracellular matrix (inferred) | NW_004936562 | 4802282 | 4949500 | Squirrel | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18580256 | HSD17B12 | hydroxysteroid 17-beta dehydrogenase 12 | ENCODES a protein that exhibits collagen binding (inferred); estradiol 17-beta-dehydrogenase [NAD(P)+] activity (inferred); fibronectin binding (inferred); INVOLVED IN extracellular matrix organization (ortholog); positive regulation of cell-substrate adhesion (ortholog); FOUND IN endoplasmic reticu lum (inferred); endoplasmic reticulum membrane (inferred); extracellular matrix (inferred) | | | | Green Monkey | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14266213 | HSD17B12 | hydroxysteroid 17-beta dehydrogenase 12 | ENCODES a protein that exhibits collagen binding (inferred); estradiol 17-beta-dehydrogenase [NAD(P)+] activity (inferred); fibronectin binding (inferred); INVOLVED IN extracellular matrix organization (ortholog); positive regulation of cell-substrate adhesion (ortholog); FOUND IN endoplasmic reticu lum membrane (inferred); extracellular matrix (inferred); fatty acid elongase complex (inferred); INTERACTS WITH resveratrol | | | | Pig | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625947488 | Hsd17b12 | hydroxysteroid 17-beta dehydrogenase 12 | ENCODES a protein that exhibits collagen binding (ortholog); fibronectin binding (ortholog); heparin binding (ortholog); INVOLVED IN extracellular matrix organization (ortholog); fatty acid elongation, saturated fatty acid (ortholog); positive regulation of cell-substrate adhesion (ortholog); FOUND IN extracellular matrix (ortholog); fatty acid elongase complex (ortholog) | | | | Black Rat | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18907737 | Hsd17b12 | hydroxysteroid 17-beta dehydrogenase 12 | ENCODES a protein that exhibits collagen binding (ortholog); fibronectin binding (ortholog); heparin binding (ortholog); INVOLVED IN extracellular matrix organization (ortholog); fatty acid elongation, saturated fatty acid (ortholog); positive regulation of cell-substrate adhesion (ortholog); FOUND IN extracellular matrix (ortholog); fatty acid elongase complex (ortholog) | | | | Naked Mole-Rat | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155240420 | hsd17b12 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155244676 | hsd17b12.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155240421 | hsd17b12.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 38639343 | HSD17B12P1 | HSD17B12 pseudogene 1 | | 6 | 157365788 | 157366961 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 38653393 | HSD17B12P2 | HSD17B12 pseudogene 2 | | 20 | 21488015 | 21488624 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 16570225 | AC087521.4 | novel transcript, antisense HSD17B12 | | | | | Human | | name | gene, lncrna |
| 16553465 | AL133325.1 | hydroxysteroid (17-beta) dehydrogenase 12 (HSD17B12) pseudogene | | | | | Human | | name | gene, processed_pseudogene |