Herpud1 Gene Search Result

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17 records found for search term Herpud1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
620818	Herpud1	homocysteine inducible ER protein with ubiquitin like domain 1	ENCODES a protein that exhibits transmembrane transporter binding (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN intracellular calcium ion homeostasis; endoplasmic reticulum calcium ion homeostasis (ortholog); endoplasmic reticulum unfolded protein response (ort ... (more) holog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); Prostatic Neoplasms (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); endoplasmic reticulum quality control compartment (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine	19	10604360	10624168	Rat	301	symbol , PhenoGen	gene, protein-coding, PROVISIONAL [RefSeq]
733943	HERPUD1	homocysteine inducible ER protein with ubiquitin like domain 1	The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfol ... (more) ded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq, Jan 2013]	16	56932142	56944864	Human	294	symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
733944	Herpud1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	Enables ubiquitin-like ligase-substrate adaptor activity. Involved in protein targeting to ER; regulation of ERAD pathway; and regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. Acts upstream of or within endoplasmic reticulum unfolded protein response; regulat ... (more) ion of protein ubiquitination; and ubiquitin-dependent protein catabolic process. Located in endoplasmic reticulum membrane and endoplasmic reticulum quality control compartment. Is expressed in several structures, including clavicle; craniocervical region bone; early conceptus; and olfactory epithelium. Orthologous to human HERPUD1 (homocysteine inducible ER protein with ubiquitin like domain 1). [provided by Alliance of Genome Resources, Jul 2025]	8	95113057	95121999	Mouse	306	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
8873942	Herpud1	homocysteine inducible ER protein with ubiquitin like domain 1	ENCODES a protein that exhibits transmembrane transporter binding (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN endoplasmic reticulum calcium ion homeostasis (ortholog); endoplasmic reticulum unfolded protein response (ortholog); ERAD pathway (ortholog); ASSOCI ... (more) ATED WITH hereditary breast ovarian cancer syndrome (ortholog); Prostatic Neoplasms (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); endoplasmic reticulum quality control compartment (ortholog)	NW_004955433	14609275	14621774	Chinchilla	32	symbol	gene, protein-coding, MODEL [RefSeq]
11875447	HERPUD1	homocysteine inducible ER protein with ubiquitin like domain 1	ENCODES a protein that exhibits transmembrane transporter binding (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN endoplasmic reticulum unfolded protein response (ortholog); intracellular calcium ion homeostasis (ortholog); regulation of protein ubiquitination (o ... (more) rtholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); Prostatic Neoplasms (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); endoplasmic reticulum quality control compartment (inferred)	16	37210170	37221961	Bonobo	38	symbol	gene, protein-coding, MODEL [RefSeq]
12415481	HERPUD1	homocysteine inducible ER protein with ubiquitin like domain 1	ENCODES a protein that exhibits transmembrane transporter binding (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN endoplasmic reticulum unfolded protein response (ortholog); intracellular calcium ion homeostasis (ortholog); regulation of protein ubiquitination (o ... (more) rtholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); Prostatic Neoplasms (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); endoplasmic reticulum quality control compartment (inferred); INTERACTS WITH masitinib	2	59388492	59400028	Dog	39	symbol	gene, protein-coding, MODEL [RefSeq]
12477308	Herpud1	homocysteine inducible ER protein with ubiquitin like domain 1	ENCODES a protein that exhibits transmembrane transporter binding (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN endoplasmic reticulum unfolded protein response (ortholog); intracellular calcium ion homeostasis (ortholog); regulation of protein ubiquitination (o ... (more) rtholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); Prostatic Neoplasms (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); endoplasmic reticulum quality control compartment (inferred)	NW_004936475	9091115	9102101	Squirrel	38	symbol	gene, protein-coding, MODEL [RefSeq]
14128484	HERPUD1	homocysteine inducible ER protein with ubiquitin like domain 1	ENCODES a protein that exhibits transmembrane transporter binding (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN endoplasmic reticulum unfolded protein response (ortholog); intracellular calcium ion homeostasis (ortholog); regulation of protein ubiquitination (o ... (more) rtholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); Prostatic Neoplasms (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); endoplasmic reticulum quality control compartment (inferred); INTERACTS WITH deoxynivalenol				Pig	39	symbol	gene, protein-coding, MODEL [RefSeq]
18916854	Herpud1	homocysteine inducible ER protein with ubiquitin like domain 1	ENCODES a protein that exhibits transmembrane transporter binding (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN endoplasmic reticulum unfolded protein response (ortholog); intracellular calcium ion homeostasis (ortholog); regulation of protein ubiquitination (o ... (more) rtholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); Prostatic Neoplasms (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); endoplasmic reticulum quality control compartment (inferred)				Naked Mole-Rat	38	symbol	gene, protein-coding, PROVISIONAL [RefSeq]
18490779	HERPUD1	homocysteine inducible ER protein with ubiquitin like domain 1	ENCODES a protein that exhibits transmembrane transporter binding (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN endoplasmic reticulum unfolded protein response (ortholog); intracellular calcium ion homeostasis (ortholog); regulation of protein ubiquitination (o ... (more) rtholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); Prostatic Neoplasms (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); endoplasmic reticulum quality control compartment (inferred)				Green Monkey	38	symbol	gene, protein-coding, MODEL [RefSeq]
155242306	herpud1						Tropical Clawed Frog		symbol	gene, null
625888417	Herpud1	homocysteine inducible ER protein with ubiquitin like domain 1	ENCODES a protein that exhibits transmembrane transporter binding (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN endoplasmic reticulum calcium ion homeostasis (ortholog); endoplasmic reticulum unfolded protein response (ortholog); ERAD pathway (ortholog); ASSOCI ... (more) ATED WITH hereditary breast ovarian cancer syndrome (ortholog); Prostatic Neoplasms (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); endoplasmic reticulum quality control compartment (ortholog)				Black Rat	32	symbol	gene, protein-coding, MODEL [RefSeq]
155242307	herpud1.L						African Clawed Frog		symbol	gene, null
155253314	herpud1.S						African Clawed Frog		symbol	gene, null
597830040	HERPUD1-IT1	HERPUD1 intronic transcript 1					Human		symbol , GTEx , COSMIC , name , Human Proteome Map	gene, ncrna
16563105	AC012181.1	novel transcript, sense intronic to HERPUD1					Human		name	gene, lncrna
16563187	AC012181.2	novel transcript, sense intronic to HERPUD1					Human		name	gene, lncrna