| 1307950 | Glrx2 | glutaredoxin 2 | ENCODES a protein that exhibits protein-disulfide reductase activity (ortholog); INVOLVED IN cellular response to superoxide; FOUND IN dendrite; mitochondrial matrix; neuronal cell body; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol | 13 | 58032199 | 58055061 | Rat | 112 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1317443 | GLRX2 | glutaredoxin 2 | The protein encoded by this gene is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or two active cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one of which is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasis and is important for the protection against and recovery from oxidative stress. Other isoforms, which have more restrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellular differentiation and transformation, possibly with a role in tumor progression. [provided by RefSeq, Aug 2011] | 1 | 193096465 | 193106114 | Human | 125 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1317444 | Glrx2 | glutaredoxin 2 | Enables protein-disulfide reductase activity. Located in mitochondrion. Is expressed in several structures, including adrenal gland; alimentary system; genitourinary system; nervous system; and respiratory system. Orthologous to human GLRX2 (glutaredoxin 2). [pr ovided by Alliance of Genome Resources, Jul 2025] | 1 | 143614787 | 143625416 | Mouse | 120 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9045377 | Glrx2 | glutaredoxin 2 | ENCODES a protein that exhibits protein-disulfide reductase activity (ortholog); INVOLVED IN cellular response to superoxide (ortholog); FOUND IN dendrite (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog) | NW_004955406 | 30497562 | 30506463 | Chinchilla | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12003468 | GLRX2 | glutaredoxin 2 | ENCODES a protein that exhibits 2 iron, 2 sulfur cluster binding (inferred); iron-sulfur cluster binding (inferred); metal ion binding (inferred); INVOLVED IN cellular response to superoxide (ortholog); FOUND IN dendrite (ortholog); mitochondrial matrix (ortholog); neuronal cell body (ortholog) | 1 | 168555858 | 168565949 | Bonobo | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12285051 | GLRX2 | glutaredoxin 2 | ENCODES a protein that exhibits 2 iron, 2 sulfur cluster binding (inferred); iron-sulfur cluster binding (inferred); metal ion binding (inferred); INVOLVED IN cellular response to superoxide (ortholog); FOUND IN dendrite (ortholog); mitochondrial matrix (ortholog); neuronal cell body (ortholog) | 38 | 5963800 | 5971673 | Dog | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12597894 | Glrx2 | glutaredoxin 2 | ENCODES a protein that exhibits 2 iron, 2 sulfur cluster binding (inferred); iron-sulfur cluster binding (inferred); metal ion binding (inferred); INVOLVED IN cellular response to superoxide (ortholog); FOUND IN dendrite (ortholog); mitochondrial matrix (ortholog); neuronal cell body (ortholog) | NW_004936638 | 1325076 | 1333994 | Squirrel | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18909541 | Glrx2 | glutaredoxin 2 | ENCODES a protein that exhibits 2 iron, 2 sulfur cluster binding (inferred); iron-sulfur cluster binding (inferred); metal ion binding (inferred); INVOLVED IN cellular response to superoxide (ortholog); FOUND IN dendrite (ortholog); mitochondrial matrix (ortholog); neuronal cell body (ortholog) | | | | Naked Mole-Rat | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625980303 | Glrx2 | glutaredoxin 2 | ENCODES a protein that exhibits protein-disulfide reductase activity (ortholog); INVOLVED IN cellular response to superoxide (ortholog); FOUND IN dendrite (ortholog); mitochondrial matrix (ortholog); mitochondrion (ortholog) | | | | Black Rat | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18673128 | GLRX2 | glutaredoxin 2 | ENCODES a protein that exhibits 2 iron, 2 sulfur cluster binding (inferred); iron-sulfur cluster binding (inferred); metal ion binding (inferred); INVOLVED IN cellular response to superoxide (ortholog); FOUND IN dendrite (ortholog); mitochondrial matrix (ortholog); neuronal cell body (ortholog) | | | | Green Monkey | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14142946 | GLRX2 | glutaredoxin 2 | ENCODES a protein that exhibits 2 iron, 2 sulfur cluster binding (inferred); iron-sulfur cluster binding (inferred); metal ion binding (inferred); INVOLVED IN cellular response to superoxide (ortholog); FOUND IN dendrite (ortholog); mitochondrial matrix (ortholog); neuronal cell body (ortholog) | | | | Pig | 13 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 155259919 | glrx2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155259545 | glrx2.L | | | | | | African Clawed Frog | | symbol | gene, null |