| 1309225 | Eif4a2 | eukaryotic translation initiation factor 4A2 | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of RNA-dependent RNA polymerase activity (ortholog); PARTICIPATES IN translation initiation pathway; RNA transport pathway; ASSOCIATED WITH genetic disease (ortholog); Neoplasm Metastasis (ortholog); neurodevelopmental disorder with hypotonia and speech delay (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 11 | 91268730 | 91276738 | Rat | 183 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1319448 | EIF4A2 | eukaryotic translation initiation factor 4A2 | Enables ATP hydrolysis activity. Involved in negative regulation of RNA-dependent RNA polymerase activity. Located in perinuclear region of cytoplasm. Implicated in neurodevelopmental disorder with hypotonia and speech delay. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 186783577 | 186789897 | Human | 278 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1319449 | Eif4a2 | eukaryotic translation initiation factor 4A2 | Predicted to enable ATP hydrolysis activity and translation initiation factor activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in perinuclear region of cytoplasm. Predicted to be part of eukaryotic translation initiation factor 4F complex. Is expressed in brain; early conceptus; oocyte; and telencephalon. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with hypotonia and speech delay. Orthologous to human EIF4A2 (eukaryotic translation initiation factor 4A2). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 22924846 | 22932882 | Mouse | 197 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8864543 | Eif4a2 | eukaryotic translation initiation factor 4A2 | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of RNA-dependent RNA polymerase activity (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH genetic disease (orthol og); Neoplasm Metastasis (ortholog); neurodevelopmental disorder with hypotonia and speech delay (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog) | NW_004955420 | 20967848 | 20974093 | Chinchilla | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11863477 | EIF4A2 | eukaryotic translation initiation factor 4A2 | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); helicase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of RNA-dependent RNA polymerase activity (ortholog); PARTICIPATES IN translation initi ation pathway; ASSOCIATED WITH genetic disease (ortholog); Neoplasm Metastasis (ortholog); neurodevelopmental disorder with hypotonia and speech delay (ortholog); FOUND IN eukaryotic translation initiation factor 4F complex (inferred); perinuclear region of cytoplasm (inferred) | 3 | 183818449 | 183824870 | Bonobo | 36 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12198342 | EIF4A2 | eukaryotic translation initiation factor 4A2 | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); helicase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of RNA-dependent RNA polymerase activity (ortholog); PARTICIPATES IN translation initi ation pathway; ASSOCIATED WITH genetic disease (ortholog); Neoplasm Metastasis (ortholog); neurodevelopmental disorder with hypotonia and speech delay (ortholog); FOUND IN perinuclear region of cytoplasm (inferred) | 34 | 19354739 | 19361021 | Dog | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12704332 | Eif4a2 | eukaryotic translation initiation factor 4A2 | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of RNA-dependent RNA polymerase activity (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH genetic disease (orthol og); Neoplasm Metastasis (ortholog); neurodevelopmental disorder with hypotonia and speech delay (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog) | NW_004936578 | 3219842 | 3225261 | Squirrel | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18909804 | Eif4a2 | eukaryotic translation initiation factor 4A2 | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of RNA-dependent RNA polymerase activity (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH genetic disease (orthol og); Neoplasm Metastasis (ortholog); neurodevelopmental disorder with hypotonia and speech delay (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog) | | | | Naked Mole-Rat | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14187140 | EIF4A2 | eukaryotic translation initiation factor 4A2 | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); helicase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of RNA-dependent RNA polymerase activity (ortholog); PARTICIPATES IN translation initi ation pathway; ASSOCIATED WITH genetic disease (ortholog); Neoplasm Metastasis (ortholog); neurodevelopmental disorder with hypotonia and speech delay (ortholog); FOUND IN perinuclear region of cytoplasm (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 28 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 155245903 | eif4a2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18724616 | EIF4A2 | eukaryotic translation initiation factor 4A2 | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); helicase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of RNA-dependent RNA polymerase activity (ortholog); PARTICIPATES IN translation initi ation pathway; ASSOCIATED WITH genetic disease (ortholog); Neoplasm Metastasis (ortholog); neurodevelopmental disorder with hypotonia and speech delay (ortholog); FOUND IN eukaryotic translation initiation factor 4F complex (inferred); perinuclear region of cytoplasm (inferred) | | | | Green Monkey | 36 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625862060 | Eif4a2 | eukaryotic translation initiation factor 4A2 | ENCODES a protein that exhibits ATP hydrolysis activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of RNA-dependent RNA polymerase activity (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH genetic disease (orthol og); Neoplasm Metastasis (ortholog); neurodevelopmental disorder with hypotonia and speech delay (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog) | | | | Black Rat | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155252491 | eif4a2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 41022417 | Eif4a2-ps1 | eukaryotic translation initiation factor 4A2, pseudogene 1 | | 15 | 94367395 | 94370608 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1597031 | Eif4a2-ps2 | eukaryotic translation initiation factor 4A2, pseudogene 2 | | 6 | 20463164 | 20464310 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1315119 | Eif4b | eukaryotic translation initiation factor 4B | Predicted to enable RNA strand annealing activity; RNA strand-exchange activity; and ribosomal small subunit binding activity. Predicted to be involved in eukaryotic translation initiation factor 4F complex assembly and formation of translation preinitiation complex. Predicted to be located in cytos ol; dendrite; and neuronal cell body. Orthologous to human EIF4B (eukaryotic translation initiation factor 4B). [provided by Alliance of Genome Resources, Apr 2025] | 15 | 101982208 | 102005608 | Mouse | 213 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 16563809 | AC112907.3 | novel transcript, antisense to eukaryotic translation initiation factor 4A, isoform 2 EIF4A2 | | | | | Human | | name | gene, lncrna |
| 3103083 | EIF4A2P1 | eukaryotic translation initiation factor 4A2 pseudogene 1 | | 18 | 12912805 | 12914206 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 7241116 | EIF4A2P2 | eukaryotic translation initiation factor 4A2 pseudogene 2 | | 10 | 73200355 | 73201425 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 7256436 | EIF4A2P3 | eukaryotic translation initiation factor 4A2 pseudogene 3 | | 11 | 58241843 | 58243129 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 7240942 | EIF4A2P4 | eukaryotic translation initiation factor 4A2 pseudogene 4 | INTERACTS WITH arsenous acid; chloropicrin; diarsenic trioxide | X | 52832643 | 52833933 | Human | 8 | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 10400724 | EIF4A2P5 | eukaryotic translation initiation factor 4A2 pseudogene 5 | | 11 | 32085111 | 32085712 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 12420162 | ADIPOQ | adiponectin, C1Q and collagen domain containing | ENCODES a protein that exhibits hormone activity (ortholog); identical protein binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN brown fat cell differentiation (ortholog); cellular response to cAMP (ortholog); cellular response to epinephrine stimulus (ortholog); PARTICIPATES IN adiponectin signaling pathway; ASSOCIATED WITH Acute Lung Injury (ortholog); Alzheimer's disease (ortholog); amyloidosis (ortholog); FOUND IN cell periphery (ortholog); cell surface (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH bisphenol A | 34 | 19398310 | 19410519 | Dog | 341 | ensembl_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |