| 1346890 | CCNO | cyclin O | This gene encodes a member of the cyclin protein family, and the encoded protein is involved in regulation of the cell cycle. Disruption of this gene is associated with primary ciliary dyskinesia-19. Alternative splicing results in multiple transcript variants. This gene, which has a previous symbol of UNG2, was erroneously identified as a uracil DNA glycosylase in PubMed ID: 2001396. A later publication, PubMed ID: 8419333, identified this gene's product as a cyclin protein family member. The UNG2 symbol is also used as a specific protein isoform name for the UNG gene (GeneID 7374), so confusion exists in the scientific literature and in some databases for these two genes. [provided by RefSeq, Jul 2014] | 5 | 55231152 | 55233608 | Human | 185 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1565217 | Ccno | cyclin O | ENCODES a protein that exhibits protein kinase binding (inferred); INVOLVED IN response to xenobiotic stimulus; cilium assembly (ortholog); mitotic cell cycle (ortholog); ASSOCIATED WITH genetic disease (ortholog); obstructive lung disease (ortholog); primary ciliary dyskinesia (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A | 2 | 46364074 | 46367113 | Rat | 100 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1622097 | Ccno | cyclin O | Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Acts upstream of or within several processes, including cilium assembly; seminiferous tubule development; and spermatogenesis. Located in cytoplasm. Is expressed in brain; nasal epithelium; reproductive system; and trachea. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 29. Orthologous to human CCNO (cyclin O). [provided by Alliance of Genome Resources, Jul 2025] | 13 | 113124363 | 113127313 | Mouse | 122 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8767896 | Ccno | cyclin O | INVOLVED IN cilium assembly (ortholog); mitotic cell cycle (ortholog); multi-ciliated epithelial cell differentiation (ortholog); ASSOCIATED WITH genetic disease (ortholog); obstructive lung disease (ortholog); primary ciliary dyskinesia (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortholog ) | NW_004955446 | 12432889 | 12435435 | Chinchilla | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11874683 | CCNO | cyclin O | INVOLVED IN cilium assembly (ortholog); response to xenobiotic stimulus (ortholog); seminiferous tubule development (ortholog); ASSOCIATED WITH genetic disease (ortholog); obstructive lung disease (ortholog); primary ciliary dyskinesia (ortholog); FOUND IN cytoplasm (inferred); nucleolus (inferred) | 5 | 58796177 | 58798797 | Bonobo | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12415034 | CCNO | cyclin O | INVOLVED IN cilium assembly (ortholog); response to xenobiotic stimulus (ortholog); seminiferous tubule development (ortholog); ASSOCIATED WITH genetic disease (ortholog); obstructive lung disease (ortholog); primary ciliary dyskinesia (ortholog); FOUND IN cytoplasm (inferred); nucleolus (inferred) | 2 | 42587293 | 42589865 | Dog | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12583399 | Ccno | cyclin O | INVOLVED IN cilium assembly (ortholog); response to xenobiotic stimulus (ortholog); seminiferous tubule development (ortholog); ASSOCIATED WITH genetic disease (ortholog); obstructive lung disease (ortholog); primary ciliary dyskinesia (ortholog); FOUND IN cytoplasm (inferred); nucleolus (inferred) | NW_004936480 | 12526391 | 12529384 | Squirrel | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18782758 | CCNO | cyclin O | INVOLVED IN cilium assembly (ortholog); response to xenobiotic stimulus (ortholog); seminiferous tubule development (ortholog); ASSOCIATED WITH genetic disease (ortholog); obstructive lung disease (ortholog); primary ciliary dyskinesia (ortholog); FOUND IN cytoplasm (inferred); nucleolus (inferred) | | | | Green Monkey | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155248604 | ccno | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 20867281 | CCNO | cyclin O | | | | | Green Monkey | | symbol | gene, protein-coding |
| 625952408 | Ccno | cyclin O | INVOLVED IN cilium assembly (ortholog); mitotic cell cycle (ortholog); multi-ciliated epithelial cell differentiation (ortholog); ASSOCIATED WITH genetic disease (ortholog); obstructive lung disease (ortholog); primary ciliary dyskinesia (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortholog ) | | | | Black Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14047712 | CCNO | cyclin O | INVOLVED IN cilium assembly (ortholog); response to xenobiotic stimulus (ortholog); seminiferous tubule development (ortholog); ASSOCIATED WITH genetic disease (ortholog); obstructive lung disease (ortholog); primary ciliary dyskinesia (ortholog); FOUND IN cytoplasm (inferred); nucleolus (inferred) | | | | Pig | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18908842 | Ccno | cyclin O | ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase regulator activity (inferred); INVOLVED IN cilium assembly (ortholog); mitotic cell cycle (ortholog); multi-ciliated epithelial cell differentiation (ortholog); ASSOCIATED WITH genetic disease (ortholog); obstructive lu ng disease (ortholog); primary ciliary dyskinesia (ortholog); FOUND IN nucleolus (ortholog) | | | | Naked Mole-Rat | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155246889 | ccno.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155234097 | ccno.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 126775159 | CCNO-DT | CCNO divergent transcript | ASSOCIATED WITH prostate cancer | 5 | 55233894 | 55295302 | Human | 1 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 16559202 | CCNO-DT | CCNO divergent transcript | | | | | Human | | symbol , COSMIC , name , Human Proteome Map | gene, lncrna |
| 1605985 | ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | The protein encoded by this gene is involved in plasma membrane electron transport pathways. The encoded protein has both a hydroquinone (NADH) oxidase activity and a protein disulfide-thiol interchange activity. The two activities cycle with a periodicity of 24 minutes, with one activity being at i ts peak when the other is at its lowest. [provided by RefSeq, Dec 2016] | 13 | 43213130 | 43786972 | Human | 90 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1316252 | UNG | uracil DNA glycosylase | This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine dea mination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010] | 12 | 109097597 | 109110992 | Human | 288 | description | gene, protein-coding, REVIEWED [RefSeq] |
