| 1308944 | Bnip2 | BCL2 interacting protein 2 | INVOLVED IN response to oxygen-glucose deprivation; blastocyst development (ortholog); centrosome cycle (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; FOUND IN centriole (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl )ethane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 8 | 79521375 | 79539148 | Rat | 93 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1319009 | BNIP2 | BCL2 interacting protein 2 | This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] | 15 | 59659146 | 59689320 | Human | 100 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1319010 | Bnip2 | BCL2/adenovirus E1B interacting protein 2 | Acts upstream of or within several processes, including blastocyst development; centrosome cycle; and positive regulation of intracellular signal transduction. Located in centriole and spindle pole centrosome. Is expressed in neocortex. Orthologous to human BNIP2 > (BCL2 interacting protein 2). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 69896660 | 69918941 | Mouse | 113 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8877928 | Bnip2 | BCL2 interacting protein 2 | INVOLVED IN blastocyst development (ortholog); centrosome cycle (ortholog); positive regulation of MAPK cascade (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; FOUND IN centriole (ortholog); cytoplasm (ortholog); cytosol (ortholog) | NW_004955450 | 15157411 | 15180069 | Chinchilla | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12036223 | BNIP2 | BCL2 interacting protein 2 | INVOLVED IN blastocyst development (ortholog); centrosome cycle (ortholog); positive regulation of MAPK cascade (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; FOUND IN cytosol (ortholog); nuclear envelope (ortholog) | 15 | 38628798 | 38659161 | Bonobo | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12167193 | BNIP2 | BCL2 interacting protein 2 | INVOLVED IN blastocyst development (ortholog); centrosome cycle (ortholog); positive regulation of MAPK cascade (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; FOUND IN centriole (inferred); cytoplasm (inferred); cytosol (inferred) | 30 | 24522397 | 24546968 | Dog | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12643002 | Bnip2 | BCL2 interacting protein 2 | INVOLVED IN blastocyst development (ortholog); centrosome cycle (ortholog); positive regulation of MAPK cascade (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; FOUND IN centriole (inferred); cytoplasm (inferred); cytosol (inferred) | NW_004936471 | 20655415 | 20675351 | Squirrel | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14013889 | BNIP2 | BCL2 interacting protein 2 | INVOLVED IN blastocyst development (ortholog); centrosome cycle (ortholog); positive regulation of MAPK cascade (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; FOUND IN centriole (inferred); cytoplasm (inferred); cytosol (inferred) | | | | Pig | 22 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 18636030 | BNIP2 | BCL2 interacting protein 2 | INVOLVED IN blastocyst development (ortholog); centrosome cycle (ortholog); positive regulation of MAPK cascade (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; FOUND IN centriole (inferred); cytoplasm (inferred); cytosol (inferred) | | | | Green Monkey | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18914308 | Bnip2 | BCL2 interacting protein 2 | INVOLVED IN blastocyst development (ortholog); centrosome cycle (ortholog); positive regulation of MAPK cascade (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; FOUND IN centriole (ortholog); cytosol (ortholog); nuclear envelope (ortholog) | | | | Naked Mole-Rat | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155244575 | bnip2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625861129 | Bnip2 | BCL2 interacting protein 2 | INVOLVED IN blastocyst development (ortholog); centrosome cycle (ortholog); positive regulation of MAPK cascade (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; FOUND IN centriole (ortholog); cytoplasm (ortholog); cytosol (ortholog) | | | | Black Rat | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 405856470 | bnip2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405856711 | bnip2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405857561 | bnip2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405864581 | bnip2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626469752 | bnip2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155244576 | bnip2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1586082 | Bnip2-ps1 | BCL2 interacting protein 2, pseudogene 1 | | 5 | 53075614 | 53077474 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 16562097 | AC092755.2 | novel transcript, antisense to BNIP2 | | | | | Human | | name | gene, lncrna |
| 16553708 | AC092755.1 | novel transcript, sense overlapping BNIP2 and GTF2A2 | | | | | Human | | name | gene, lncrna |
| 1311350 | Prune2 | prune homolog 2 with BCH domain | INVOLVED IN apoptotic process (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN glutamatergic synapse (ortholog); presynapse (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane | 1 | 223779617 | 224130058 | Rat | 109 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1322392 | PRUNE2 | prune homolog 2 with BCH domain | The protein encoded by this gene belongs to the B-cell CLL/lymphoma 2 and adenovirus E1B 19 kDa interacting family, whose members play roles in many cellular processes including apotosis, cell transformation, and synaptic function. Several functions for this protein have been demonstrated including suppression of Ras homolog family member A activity, which results in reduced stress fiber formation and suppression of oncogenic cellular transformation. A high molecular weight isoform of this protein has also been shown to colocalize with Adaptor protein complex 2, beta-Adaptin and endodermal markers, suggesting an involvement in post-endocytic trafficking. In prostate cancer cells, this gene acts as a tumor suppressor and its expression is regulated by prostate cancer antigen 3, a non-protein coding gene on the opposite DNA strand in an intron of this gene. Prostate cancer antigen 3 regulates levels of this gene through formation of a double-stranded RNA that undergoes adenosine deaminase actin on RNA-dependent adenosine-to-inosine RNA editing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] | 9 | 76611376 | 76906114 | Human | 114 | old_gene_name | gene, protein-coding, REVIEWED [RefSeq] |
| 1322761 | Prune2 | prune homolog 2 | Predicted to enable pyrophosphatase activity. Predicted to be involved in apoptotic process. Is active in glutamatergic synapse and presynapse. Is expressed in several structures, including alimentary system; limb; nervous system; sensory organ; and urinary system. Orthologous to human PRUNE2 (prune homolog 2 with BCH domain). [provided by Alliance of Genome Resources, Jul 2025] | 19 | 16933033 | 17201322 | Mouse | 118 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
