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13 records found for search term Aplf
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1344091APLFaprataxin and PNKP like factorEnables several functions, including ADP-D-ribose modification-dependent protein binding activity; nuclease activity; and poly-ADP-D-ribose binding activity. Involved in DNA repair; DNA repair-dependent chromatin remodeling; and protein localization to chromatin. Located in nucleoplasm. Is active in26846758568580162Human127symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1565557Aplfaprataxin and PNKP like factorENCODES a protein that exhibits 3'-5' exonuclease activity (ortholog); ADP-D-ribose modification-dependent protein binding (ortholog); DNA endonuclease activity (ortholog); INVOLVED IN DNA damage response (ortholog); DNA repair (ortholog); DNA repair-dependent chromatin remodeling (ortholog); PARTIC4121627800121679980Rat117symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1619131Aplfaprataxin and PNKP like factorPredicted to enable several functions, including ADP-D-ribose modification-dependent protein binding activity; nuclease activity; and poly-ADP-D-ribose binding activity. Involved in embryo implantation and regulation of epithelial to mesenchymal transition. Acts upstream of or within double-strand b68760540787649244Mouse161symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8925769Aplfaprataxin and PNKP like factorENCODES a protein that exhibits 3'-5' exonuclease activity (ortholog); ADP-D-ribose modification-dependent protein binding (ortholog); DNA endonuclease activity (ortholog); INVOLVED IN DNA damage response (ortholog); DNA repair (ortholog); DNA repair-dependent chromatin remodeling (ortholog); PARTICNW_0049554241633854616449074Chinchilla43symbolgene, protein-coding, MODEL [RefSeq]
11963737APLFaprataxin and PNKP like factorENCODES a protein that exhibits protein folding chaperone (ortholog); INVOLVED IN double-strand break repair (ortholog); double-strand break repair via nonhomologous end joining (ortholog); embryo implantation (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; histone 2A6850931468629192Bonobo61symbolgene, protein-coding, MODEL [RefSeq]
12159348APLFaprataxin and PNKP like factorENCODES a protein that exhibits protein folding chaperone (ortholog); INVOLVED IN double-strand break repair (ortholog); double-strand break repair via nonhomologous end joining (ortholog); embryo implantation (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; histone 106745450067522659Dog59symbolgene, protein-coding, MODEL [RefSeq]
12709555Aplfaprataxin and PNKP like factorENCODES a protein that exhibits protein folding chaperone (ortholog); INVOLVED IN double-strand break repair (ortholog); double-strand break repair via nonhomologous end joining (ortholog); regulation of isotype switching (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylatiNW_0049364911285792812961709Squirrel61symbolgene, protein-coding, MODEL [RefSeq]
625938476Aplfaprataxin and PNKP like factorENCODES a protein that exhibits 3'-5' exonuclease activity (ortholog); ADP-D-ribose modification-dependent protein binding (ortholog); DNA endonuclease activity (ortholog); INVOLVED IN DNA damage response (ortholog); DNA repair (ortholog); DNA repair-dependent chromatin remodeling (ortholog); PARTICBlack Rat43symbolgene, protein-coding, MODEL [RefSeq]
18356925APLFaprataxin and PNKP like factorENCODES a protein that exhibits protein folding chaperone (ortholog); INVOLVED IN double-strand break repair (ortholog); double-strand break repair via nonhomologous end joining (ortholog); embryo implantation (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; histone Green Monkey61symbolgene, protein-coding, MODEL [RefSeq]
14162209APLFaprataxin and PNKP like factorENCODES a protein that exhibits protein folding chaperone (ortholog); INVOLVED IN double-strand break repair (ortholog); double-strand break repair via nonhomologous end joining (ortholog); embryo implantation (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; histone Pig60symbolgene, protein-coding, MODEL [RefSeq]
18928652Aplfaprataxin and PNKP like factorENCODES a protein that exhibits ADP-D-ribose modification-dependent protein binding (ortholog); DNA endonuclease activity (ortholog); histone binding (ortholog); INVOLVED IN DNA repair-dependent chromatin remodeling (ortholog); double-strand break repair (ortholog); double-strand break repair via noNaked Mole-Rat53symbolgene, protein-coding, MODEL [RefSeq]
155239351aplfTropical Clawed Frogsymbolgene, null
155239352aplf.LAfrican Clawed Frogsymbolgene, null