| 1308899 | Adamts14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | ENCODES a protein that exhibits peptidase activity (ortholog); INVOLVED IN collagen fibril organization (ortholog); ASSOCIATED WITH Fraser syndrome 3 (ortholog); osteoarthritis (ortholog); primary progressive multiple sclerosis (ortholog); FOUND IN extracellular region (ortholog); INTERACTS WITH 17b eta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 20 | 29685876 | 29762685 | Rat | 88 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1318933 | ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif 14 | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS ) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme cleaves amino-terminal propeptides from type I procollagen, a necessary step in the formation of collagen fibers. Mutations in this gene may be associated with osteoarthritis in human patients. [provided by RefSeq, May 2016] | 10 | 70672506 | 70762441 | Human | 91 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1618137 | Adamts14 | ADAM metallopeptidase with thrombospondin type 1 motif 14 | Enables peptidase activity. Acts upstream of or within collagen fibril organization. Located in extracellular region. Is expressed in vertebral axis musculature. Human ortholog(s) of this gene implicated in osteoarthritis; primary progressive multiple sclerosis; and relapsing-remitting multiple scle rosis. Orthologous to human ADAMTS14 (ADAM metallopeptidase with thrombospondin type 1 motif 14). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 61032886 | 61109447 | Mouse | 108 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8754045 | Adamts14 | ADAM metallopeptidase with thrombospondin type 1 motif 14 | ENCODES a protein that exhibits peptidase activity (ortholog); INVOLVED IN collagen fibril organization (ortholog); ASSOCIATED WITH Fraser syndrome 3 (ortholog); osteoarthritis (ortholog); primary progressive multiple sclerosis (ortholog); FOUND IN extracellular region (ortholog) | NW_004955437 | 20592278 | 20664075 | Chinchilla | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11966099 | ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif 14 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN collagen fibril organization (ortholog); ASSOCIATED WITH Fraser syndrome 3 (ortholog); osteoarthritis (ortholog); primary progressive multiple sclerosis (ortholog); FOUND IN extracellular matrix (inferred); extracellular region (inferred) | 10 | 67145400 | 67232934 | Bonobo | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12329062 | ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif 14 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN collagen fibril organization (ortholog); ASSOCIATED WITH Fraser syndrome 3 (ortholog); osteoarthritis (ortholog); primary progressive multiple sclerosis (ortholog); FOUND IN extracellular region (inferred) | 4 | 21534309 | 21612528 | Dog | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12583017 | Adamts14 | ADAM metallopeptidase with thrombospondin type 1 motif 14 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN collagen fibril organization (ortholog); ASSOCIATED WITH Fraser syndrome 3 (ortholog); osteoarthritis (ortholog); primary progressive multiple sclerosis (ortholog); FOUND IN extracellular matrix (inferred); extracellular region (inferred) | NW_004936521 | 7951176 | 8025666 | Squirrel | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18772651 | ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif 14 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN collagen fibril organization (ortholog); ASSOCIATED WITH Fraser syndrome 3 (ortholog); osteoarthritis (ortholog); primary progressive multiple sclerosis (ortholog); FOUND IN extracellular matrix (inferred); extracellular region (inferred) | | | | Green Monkey | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14041047 | ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif 14 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN collagen fibril organization (ortholog); ASSOCIATED WITH Fraser syndrome 3 (ortholog); osteoarthritis (ortholog); primary progressive multiple sclerosis (ortholog); FOUND IN extracellular region (inferred) | | | | Pig | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155237629 | adamts14 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626019141 | Adamts14 | ADAM metallopeptidase with thrombospondin type 1 motif 14 | ENCODES a protein that exhibits peptidase activity (ortholog); INVOLVED IN collagen fibril organization (ortholog); ASSOCIATED WITH Fraser syndrome 3 (ortholog); osteoarthritis (ortholog); primary progressive multiple sclerosis (ortholog); FOUND IN extracellular region (ortholog) | | | | Black Rat | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18900046 | Adamts14 | ADAM metallopeptidase with thrombospondin type 1 motif 14 | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN collagen fibril organization (ortholog); ASSOCIATED WITH Fraser syndrome 3 (ortholog); osteoarthritis (ortholog); primary progressive multiple sclerosis (ortholog); FOUND IN extracellular region (ortholog) | | | | Naked Mole-Rat | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155249376 | adamts14.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155237029 | adamts14.S | | | | | | African Clawed Frog | | symbol | gene, null |