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Strain: SHR.WKY-(D12Rat1-D12Mit3)/Tja

Symbol: SHR.WKY-(D12Rat1-D12Mit3)/Tja
Strain: SHR.WKY-(D12Rat1-D12Mit3)
Substrain: Tja
RGD ID: 9854709
Citation ID: RRID:RRRC_00738
Ontology ID: RS:0003871
Also known as: SHR.W12; RRRC:00738; SHR.WKY-(D12Rat1-D12Mit3)/Tja
Type: congenic
Source: MRC Clinical Centre, London, UK, Rat Resource and Research Center
Origin: This congenic strain was generated by introgressing the desired fragment from WKY/NCruk onto the genetic background of SHR/NCruk
Last Known Status: Unknown
Research Usage Insulin Resistance, Hypertension
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01245,071,632 - 245,071,725RGD_MAPPER_PIPELINERnor5.0
Rnor_5.0126,945,260 - 7,384,617RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.412555,108 - 555,654RGD_MAPPER_PIPELINERGSC3.4
RGSC_v3.41223,364,189 - 223,364,281RGD_MAPPER_PIPELINERGSC3.4






References


Region

Position Markers

Flank 1 / 1 (D12Rat1)
Rat AssemblyChrPosition (strand)Source
Rnor_5.0126,945,447 - 6,945,575NCBI
Rnor_5.0126,945,260 - 6,945,808NCBI
Rnor_5.0127,384,070 - 7,384,617NCBI
Rnor_5.01245,071,632 - 245,071,725NCBI
Rnor_5.0127,384,257 - 7,384,384NCBI
RGSC_v3.412555,341 - 555,467UniSTS
RGSC_v3.412555,108 - 555,654RGD
RGSC_v3.41223,364,189 - 223,364,281UniSTS
RGSC_v3.112555,108 - 555,654RGD
Celera1215,029,550 - 215,029,642UniSTS
Celera125,359,247 - 5,359,373UniSTS
RH 3.4 Map120.0UniSTS
RH 3.4 Map120.0RGD
RH 2.0 Map120.0RGD
SHRSP x BN Map125.62RGD

Flank 2 / 1 (D12Mit3)
Rat AssemblyChrPosition (strand)Source
RGSC_v3.11224,294,687 - 24,295,090RGD
Cytogenetic Map12 RGD

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Improved insulin sensitivity measured by IVITT; Reduced energy expenditure measured by whole body calorimetry; Reduced blood pressure measured by radiotelemetry; Reduced QTc-B, QTD, ST-I 2292495