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Strain Registration

Strain: SHRSP.SHR-(D1Mgh5-D1Got87)/Izm

Symbol: SHRSP.SHR-(D1Mgh5-D1Got87)/Izm
Strain: SHRSP.SHR-(D1Mgh5-D1Got87)
Substrain: Izm
RGD ID: 7411707
Citation ID: RRID:RGD_7411707
Ontology ID: RS:0003573
Also Known As: NBRP Rat No: 0709; SHRSP.SHR-(D1Mgh5-D1Got87)/Izm; SPrch1.1
Type: congenic
Available Source: National BioResource Project for the Rat in Japan
Origination: Department of Functional Pathology, Shimane University Faculty of Medicine, Izumo, Japan
Description: male SHRSP.SHR-(D1Rat93-D1Rat269)/Izm were crossed with female SHRSP/Izm and the offsprings were intercrossed, animals were genotyped to get the desired recombinants which were then backcrossed to SHRSP/Izm
Coat Color: Albino
Inbred Generations: F11
Last Known Status: Cryopreserved Sperm
Research Usage Cardio-Hypertension
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,430,536 - 86,030,749RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0179,689,548 - 91,156,803RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0180,946,174 - 92,291,485RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4178,134,304 - 85,828,306RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View
Hypotension  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Two genomic regions of chromosomes 1 and 18 explain most of the stroke susceptibility under salt loading in stroke-prone spontaneously hypertensive rat/Izm. Gandolgor TA, etal., Hypertension. 2013 Jul;62(1):55-61. doi: 10.1161/HYPERTENSIONAHA.111.00488. Epub 2013 May 20.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D1Mgh5)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2178,430,536 - 78,430,678 (+)MAPPER
Rnor_6.0179,689,548 - 79,689,689NCBI
Rnor_5.0180,946,174 - 80,946,315UniSTS
RGSC_v3.4178,134,305 - 78,134,446UniSTS
RGSC_v3.4178,134,304 - 78,134,446RGD
RGSC_v3.1178,212,415 - 78,212,557RGD
Celera172,898,184 - 72,898,325UniSTS
RH 3.4 Map1791.5UniSTS
RH 3.4 Map1791.5RGD
RH 2.0 Map1501.0RGD
SHRSP x BN Map140.2499RGD
FHH x ACI Map140.1RGD
Cytogenetic Map1q21UniSTS

Flank 2 / 1 (D1Got87)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2186,030,510 - 86,030,749 (+)MAPPER
Rnor_6.0191,156,565 - 91,156,803NCBI
Rnor_6.0189,228,970 - 89,229,208NCBI
Rnor_5.0192,291,247 - 92,291,485UniSTS
Rnor_5.0190,385,411 - 90,385,649UniSTS
RGSC_v3.4185,828,067 - 85,828,306RGD
RGSC_v3.4185,828,068 - 85,828,306UniSTS
RGSC_v3.1185,906,179 - 85,906,417RGD
Celera180,401,941 - 80,402,179UniSTS
RH 3.4 Map1844.0UniSTS
RH 3.4 Map1844.0RGD
RH 2.0 Map1559.7RGD
Cytogenetic Map1q21UniSTS

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease This rat has less incidence of a stroke caused by salt loading than SHRSP rat. 1302502

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-05-27 SHRSP.SHR-(D1Mgh5-D1Got87)/Izm    SHRSP.SHR-(D1Mgh5-D1Got87)/Izm    Name updated 68913 APPROVED
2015-05-27 SHRSP.SHR-(D1Mgh5-D1Got87)/Izm    SHRSP.SHR-(D1Mgh5-D1Got87)/Izm    Name updated 68913 APPROVED