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Strain Registration

Strain: SHRSP.SHR-(D1Rat93-D1Rat269)(D18Rat73-D18Rat11)/Izm

Symbol: SHRSP.SHR-(D1Rat93-D1Rat269)(D18Rat73-D18Rat11)/Izm
Strain: SHRSP.SHR-(D1Rat93-D1Rat269)(D18Rat73-D18Rat11)
Substrain: Izm
RGD ID: 7411703
Citation ID: RRID:RGD_7411703
Ontology ID: RS:0003571
Also Known As: NBRP Rat No: 0708; SHRSP.SHR-(D1Rat93-D1Rat269)(D18Rat73-D18Rat11)/Izm; SPrch1_18
Type: congenic
Available Source: National BioResource Project for the Rat in Japan
Origination: Department of Functional Pathology, Shimane University Faculty of Medicine, Izumo, Japan
Description: constructed by crossing and backcrossing the congenic strains for chr 1 and chr 18 segments
Coat Color: Albino
Inbred Generations: F11
Last Known Status: Cryopreserved Sperm
Research Usage Cardio-Hypertension
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2165,677,942 - 124,977,364RGD_MAPPER_PIPELINEmRatBN7.2
mRatBN7.21849,999,958 - 68,414,117RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01851,609,032 - 70,803,264RGD_MAPPER_PIPELINERnor6.0
Rnor_6.0164,252,881 - 132,448,306RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01850,804,228 - 69,942,605RGD_MAPPER_PIPELINERnor5.0
Rnor_5.0163,244,295 - 133,485,967RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41852,290,789 - 71,692,408RGD_MAPPER_PIPELINERGSC3.4
RGSC_v3.4163,990,899 - 126,292,805RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Two genomic regions of chromosomes 1 and 18 explain most of the stroke susceptibility under salt loading in stroke-prone spontaneously hypertensive rat/Izm. Gandolgor TA, etal., Hypertension. 2013 Jul;62(1):55-61. doi: 10.1161/HYPERTENSIONAHA.111.00488. Epub 2013 May 20.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D1Rat93)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2165,677,942 - 65,678,123 (+)MAPPER
Rnor_6.0164,252,881 - 64,253,061NCBI
Rnor_5.0163,244,295 - 63,244,475UniSTS
RGSC_v3.4163,990,899 - 63,991,255RGD
RGSC_v3.4163,990,910 - 63,991,090UniSTS
RGSC_v3.1164,067,649 - 64,067,829RGD
Celera163,401,914 - 63,402,094UniSTS
RH 3.4 Map1740.2RGD
RH 3.4 Map1740.2UniSTS
RH 2.0 Map1460.8RGD
FHH x ACI Map133.7599RGD
Cytogenetic Map1q12UniSTS

Flank 2 / 1 (D1Rat269)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21124,977,174 - 124,977,364 (+)MAPPER
Rnor_6.01132,448,117 - 132,448,306NCBI
Rnor_5.01133,485,778 - 133,485,967UniSTS
RGSC_v3.41126,292,616 - 126,292,805UniSTS
RGSC_v3.41126,292,615 - 126,292,805RGD
RGSC_v3.11126,370,959 - 126,371,148RGD
Celera1117,133,184 - 117,133,371UniSTS
RH 3.4 Map1979.2RGD
RH 3.4 Map1979.2UniSTS
RH 2.0 Map1663.9RGD
SHRSP x BN Map160.8499RGD

Flank 1 / 2 (D18Rat73)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21849,999,958 - 50,000,167 (+)MAPPER
Rnor_6.01851,609,032 - 51,609,240NCBI
Rnor_5.01850,804,228 - 50,804,436UniSTS
RGSC_v3.41852,290,789 - 52,291,194RGD
RGSC_v3.41852,290,924 - 52,291,132UniSTS
RGSC_v3.11852,336,284 - 52,336,689RGD
Celera1848,145,282 - 48,145,490UniSTS
SHRSP x BN Map1819.1999RGD
SHRSP x BN Map1819.1999UniSTS

Flank 2 / 2 (D18Rat11)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21868,413,983 - 68,414,117 (+)MAPPER
Rnor_6.01870,803,131 - 70,803,264NCBI
Rnor_5.01869,942,468 - 69,942,605UniSTS
RGSC_v3.41871,692,275 - 71,692,408UniSTS
RGSC_v3.41871,692,274 - 71,692,408RGD
RGSC_v3.11871,765,476 - 71,765,609RGD
Celera1866,590,295 - 66,590,428UniSTS
RH 3.4 Map18698.1RGD
RH 3.4 Map18698.1UniSTS
RH 2.0 Map18211.5RGD
FHH x ACI Map1847.4699RGD

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease The incidence rate of a stroke caused by salt loading is drastically reduced in this rat than in SHRSP rat. 1302502

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-05-27 SHRSP.SHR-(D1Rat93-D1Rat269)(D18Rat73-D18Rat11)/Izm    SHRSP.SHR-(D1Rat93-D1Rat269)(D18Rat73-D18Rat11)/Izm    Name updated 68913 APPROVED
2015-05-27 SHRSP.SHR-(D1Rat93-D1Rat269)(D18Rat73-D18Rat11)/Izm    SHRSP.SHR-(D1Rat93-D1Rat269)(D18Rat73-D18Rat11)/Izm    Name updated 68913 APPROVED