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Strain Registration

Strain: BDII/Ztm

Symbol: BDII/Ztm
Strain: BDII
Substrain: Ztm
RGD ID: 737947
Citation ID: RRID:RGD_737947
Ontology ID: RS:0000087
Previously known as: MDC-03-59
Type: inbred
Source: Zentralinstitut fur Versuchstierzucht, Hannover, Germany
Origin: Substrain of BDII, from cross between BDI and outbred Wistar stock to form single mating pair, with selection for coat color alleles (Druckrey 1971)
Last Known Status: Unknown





Experimental Data Annotations    Click to see Annotation Detail View

Rat Strain
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
BDII/Ztm  IEA 7241799 RGD 

Vertebrate Trait
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
uterus morphology trait  EXP 1599856update to integrity traitRGD 


References

References - curated
# Reference Title Reference Citation
1. Biochemical markers in inbred strains of the rat (Rattus norvegicus). Bender K, etal., Immunogenetics 1984;19(3):257-66.
2. Genetic characterization of inbred strains of the rat (Rattus norvegicus). Bender K, etal., J Exp Anim Sci 1994 Aug;36(4-5):151-65.
3. Sequencing and chromosomal localization of Fabp6 and an intronless Fabp6 segment in the rat. Bonne A, etal., Mol Biol Rep 2003 Sep;30(3):173-6.
4. Polymorphisms of the glucocorticoid receptor gene in laboratory and wild rats: steroid binding properties of trinucleotide CAG repeat length variants. Heeley RP, etal., Mamm Genome 1998 Mar;9(3):198-203.
5. Institute for Animal Experimentation University of Tokushima School of Medicine Institute for Animal Experimentation University of Tokushima School of Medicine
6. Use of simple sequence length polymorphisms for genetic characterization of rat inbred strains. Otsen M, etal., Mamm Genome 1995 Sep;6(9):595-601.
7. RGD Strain RSO annotation pipeline RGD Automated Pipelines
8. Genetic analysis of susceptibility to endometrial adenocarcinoma in the BDII rat model. Roshani L, etal., Cancer Genet Cytogenet. 2005 Apr 15;158(2):137-41.
9. Genetic identification of multiple susceptibility genes involved in the development of endometrial carcinoma in a rat model. Roshani L, etal., Int J Cancer. 2001 Dec 15;94(6):795-9.
10. SNP and haplotype mapping for genetic analysis in the rat. Saar K, etal., Nat Genet. 2008 May;40(5):560-6.
11. Genetic variation in coding regions between and within commonly used inbred rat strains. Smits BM, etal., Genome Res. 2004 Jul;14(7):1285-90.
12. Independent amplification of two gene clusters on chromosome 4 in rat endometrial cancer: identification and molecular characterization. Walentinsson A, etal., Cancer Res 2001 Nov 15;61(22):8263-73.

Region

Strain QTL Data
Symbol Name Trait
Edcs1 Endometrial carcinoma susceptibility QTL1 uterus morphology trait   (VT:0001120)    
Edcs2 Endometrial carcinoma susceptibility QTL2 uterus morphology trait   (VT:0001120)    
Edcs3 Endometrial carcinoma susceptibility QTL3 uterus morphology trait   (VT:0001120)    
Edcs4 Endometrial carcinoma susceptibility QTL 4 uterus morphology trait   (VT:0001120)    
Edcs5 Endometrial carcinoma susceptibility QTL 5 uterus morphology trait   (VT:0001120)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_phys_biochem This strain was screened for genetic polymorphisms for 100 genomic loci in 55 genes ; Polymorphisms observed in this study can be found in NCBI dbSNP under accession numbers ss12588106 - ss12588203. 737878