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Strain Registration

Strain: BN/Han

Symbol: BN/Han
Strain: BN
Substrain: Han
RGD ID: 737945
Citation ID: RRID:RGD_737945
Ontology ID: RS:0000140
Type: inbred
Available Source: Not Available
Origination: Zentralinstitut fur Versuchstierzucht, Hannover, Germany
Description: Substrain of BN, from Billingham and Silvers 1958, from Harlan Rijnswijk to Dr. H.J. Hedrich, Hannover, Germany in 1973.
Last Known Status: Unknown





Experimental Data Annotations    Click to see Annotation Detail View

Rat Strain
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
BN/HanRatBN/Han  IEA 7241799 RGD 

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
BN/HanRatnervous system integrity trait  EXP 2311085 RGD 
BN/HanRatuterus morphology trait  EXP 1599856update to integrity traitRGD 


References

References - curated
# Reference Title Reference Citation
1. Biochemical markers in inbred strains of the rat (Rattus norvegicus). Bender K, etal., Immunogenetics 1984;19(3):257-66.
2. Genetic characterization of inbred strains of the rat (Rattus norvegicus). Bender K, etal., J Exp Anim Sci 1994 Aug;36(4-5):151-65.
3. Identification of gene regions regulating inflammatory microglial response in the rat CNS after nerve injury. Diez M, etal., J Neuroimmunol. 2009 Jun 12.
4. Polymorphisms of the glucocorticoid receptor gene in laboratory and wild rats: steroid binding properties of trinucleotide CAG repeat length variants. Heeley RP, etal., Mamm Genome 1998 Mar;9(3):198-203.
5. Institute for Animal Experimentation University of Tokushima School of Medicine Institute for Animal Experimentation University of Tokushima School of Medicine
6. RGD Strain RSO annotation pipeline RGD Automated Pipelines
7. Genetic identification of multiple susceptibility genes involved in the development of endometrial carcinoma in a rat model. Roshani L, etal., Int J Cancer. 2001 Dec 15;94(6):795-9.
8. Genetic variation in coding regions between and within commonly used inbred rat strains. Smits BM, etal., Genome Res. 2004 Jul;14(7):1285-90.

Region

Strain QTL Data
Symbol Name Trait
Edcs2 Endometrial carcinoma susceptibility QTL2 uterus morphology trait   (VT:0001120)    
Edcs3 Endometrial carcinoma susceptibility QTL3 uterus morphology trait   (VT:0001120)    
Neuinf10 Neuroinflammation QTL 10 nervous system integrity trait   (VT:0010566)    
Neuinf11 Neuroinflammation QTL 11 nervous system integrity trait   (VT:0010566)    
Neuinf12 Neuroinflammation QTL 12 nervous system integrity trait   (VT:0010566)    
Neuinf4 Neuroinflammation QTL 4 nervous system integrity trait   (VT:0010566)    
Neuinf5 Neuroinflammation QTL 5 nervous system integrity trait   (VT:0010566)    
Neuinf6 Neuroinflammation QTL 6 nervous system integrity trait   (VT:0010566)    
Neuinf7 Neuroinflammation QTL 7 nervous system integrity trait   (VT:0010566)    
Neuinf8 Neuroinflammation QTL 8 nervous system integrity trait   (VT:0010566)    
Neuinf9 Neuroinflammation QTL 9 nervous system integrity trait   (VT:0010566)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_phys_biochem This strain was screened for genetic polymorphisms for 100 genomic loci in 55 genes ; Polymorphisms observed in this study can be found in NCBI dbSNP under accession numbers ss12588106 - ss12588203. 737878