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Strain: MWF/Hsd

Symbol: MWF/Hsd
Strain: MWF
Substrain: Hsd
Full Name: Munich Wistar Fromter
RGD ID: 737906
Citation ID: RRID:RGD_737906
Ontology ID: RS:0000593
Previously known as: MDC-03-68; MWF/ZtmHsd
Type: inbred
Source: Harlan
Origin: Substrain of Munich Wistar stock, inbred by Harlan Sprague Dawley
Last Known Status: Unknown (as of 2020-04-03)





Disease Annotations     Click to see Annotation Detail View


References

References - curated
# Reference Title Reference Citation
1. Genetic characterization of inbred strains of the rat (Rattus norvegicus). Bender K, etal., J Exp Anim Sci 1994 Aug;36(4-5):151-65.
2. Sequencing and chromosomal localization of Fabp6 and an intronless Fabp6 segment in the rat. Bonne A, etal., Mol Biol Rep 2003 Sep;30(3):173-6.
3. Polymorphisms of the glucocorticoid receptor gene in laboratory and wild rats: steroid binding properties of trinucleotide CAG repeat length variants. Heeley RP, etal., Mamm Genome 1998 Mar;9(3):198-203.
4. Institute for Animal Experimentation University of Tokushima School of Medicine Institute for Animal Experimentation University of Tokushima School of Medicine
5. Is survival time after hemorrhage a heritable, quantitative trait?: an initial assessment. Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53.
6. Use of simple sequence length polymorphisms for genetic characterization of rat inbred strains. Otsen M, etal., Mamm Genome 1995 Sep;6(9):595-601.
7. RGD Strain RSO annotation pipeline RGD Automated Pipelines
8. SNP and haplotype mapping for genetic analysis in the rat. Saar K, etal., Nat Genet. 2008 May;40(5):560-6.
9. Genetic variation in coding regions between and within commonly used inbred rat strains. Smits BM, etal., Genome Res. 2004 Jul;14(7):1285-90.
10. Increased cardiovascular risk in rats with primary renal dysfunction; mediating role for vascular endothelial function. Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.
11. Proteinuria-associated endothelial dysfunction is strain dependent. Ulu N, etal., Am J Nephrol. 2009;30(3):209-17. doi: 10.1159/000218062. Epub 2009 May 5.

Region

Damaging Variants
Number of Damaging Variants
SampleRnor_6.0Rnor_5.0RGSC_v3.4
MWF/Hsd (2019) 2780
MWF/Hsd (2019)


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other These have shorter survival time after controlled hemorrhage than BN/HsdMcwiCrl but longer than DA/OlaHsd. 2302114
strain_phys_biochem This strain was screened for genetic polymorphisms for 100 genomic loci in 55 genes ; Polymorphisms observed in this study can be found in NCBI dbSNP under accession numbers ss12588106 - ss12588203. 737878