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Strain Registration

Strain: WKY/Ztm

Symbol: WKY/Ztm
Strain: WKY
Substrain: Ztm
RGD ID: 737895
Citation ID: RRID:RGD_737895
Ontology ID: RS:0001070
Also Known As: MDC-03-74; WKY/HanZtm; WKY/Han
Type: inbred
Available Source: Not Available
Origination: Zentralinstitut fur Versuchstierzucht, Hannover, Germany
Description: Substrain of WKY rats maintained by Dr. H.J. Hedrich, Hannover
Last Known Status: Unknown





Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table


References

References - curated
# Reference Title Reference Citation
1. Biochemical markers in inbred strains of the rat (Rattus norvegicus). Bender K, etal., Immunogenetics 1984;19(3):257-66.
2. Genetic characterization of inbred strains of the rat (Rattus norvegicus). Bender K, etal., J Exp Anim Sci 1994 Aug;36(4-5):151-65.
3. The Mcs7 quantitative trait locus is associated with an increased susceptibility to mammary cancer in congenic rats and an allele-specific imbalance. Cotroneo MS, etal., Oncogene. 2006 Aug 17;25(36):5011-7. Epub 2006 Mar 27.
4. Polymorphisms of the glucocorticoid receptor gene in laboratory and wild rats: steroid binding properties of trinucleotide CAG repeat length variants. Heeley RP, etal., Mamm Genome 1998 Mar;9(3):198-203.
5. Institute for Animal Experimentation University of Tokushima School of Medicine Institute for Animal Experimentation University of Tokushima School of Medicine
6. Genetic identification of distinct loci controlling mammary tumor multiplicity, latency, and aggressiveness in the rat. Quan X, etal., Mamm Genome. 2006 Apr;17(4):310-21. Epub 2006 Apr 4.
7. RGD Strain RSO annotation pipeline RGD Automated Pipelines
8. SNP and haplotype mapping for genetic analysis in the rat. Saar K, etal., Nat Genet. 2008 May;40(5):560-6.
9. Genetic variation in coding regions between and within commonly used inbred rat strains. Smits BM, etal., Genome Res. 2004 Jul;14(7):1285-90.

Region

Strain QTL Data
Symbol Name Trait
Mcs16 Mammary carcinoma susceptibility QTL 16 mammary gland integrity trait   (VT:0010552)    
Mcs17 Mammary carcinoma susceptibility QTL 17 mammary gland integrity trait   (VT:0010552)    
Mcs18 Mammary carcinoma susceptibility QTL 18 mammary gland integrity trait   (VT:0010552)    
Mcs19 Mammary carcinoma susceptibility QTL 19 mammary gland integrity trait   (VT:0010552)    
Mcs20 Mammary carcinoma susceptibility QTL 20 mammary gland integrity trait   (VT:0010552)    
Mcs21 Mammary carcinoma susceptibility QTL 21 mammary gland integrity trait   (VT:0010552)    
Mcs22 Mammary carcinoma susceptibility QTL 22 mammary gland integrity trait   (VT:0010552)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_phys_biochem This strain was screened for genetic polymorphisms for 100 genomic loci in 55 genes ; Polymorphisms observed in this study can be found in NCBI dbSNP under accession numbers ss12588106 - ss12588203. 737878

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-03-21 WKY/Ztm    WKY/HanZtm    Symbol updated 68687 APPROVED
2011-03-21 WKY/Ztm    WKY/HanZtm    Name updated 68913 APPROVED
2011-03-21 WKY/Ztm    WKY/HanZtm    Symbol updated 68687 APPROVED
2011-03-21 WKY/Ztm    WKY/HanZtm    Name updated 68913 APPROVED