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Strain: LAD2

Symbol: LAD2
Strain: LAD2
Full Name: low-alcohol-drinking
RGD ID: 731188
Citation ID: RRID:RGD_731188
Ontology ID: RS:0000425
Type: inbred
Source: Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana
Origin: These were developed by selective breeding for alcohol preference and consumption from the heterogeneous N/N strain. 8 inbred rat strains were intercrossed. After 26 generations of selective breeding, six reciprocal matings were done between HAD1 and LAD1 rats. From each of the 6 parental litters, three brother-sister sets of F1(HAD1?LAD1) rats were chosen and bred to yeild 459 F2 offsprings.
Last Known Status: Unknown


References - curated
# Reference Title Reference Citation
1. Analyses of quantitative trait loci contributing to alcohol preference in HAD1/LAD1 and HAD2/LAD2 rats. Carr LG, etal., Alcohol Clin Exp Res 2003 Nov;27(11):1710-7.
2. Identification of quantitative trait loci influencing alcohol consumption in the high alcohol drinking and low alcohol drinking rat lines. Foroud T, etal., Behav Genet 2000 Mar;30(2):131-40.
3. Confirmation of alcohol preference quantitative trait loci in the replicate high alcohol drinking and low alcohol drinking rat lines. Foroud T, etal., Psychiatr Genet 2003 Sep;13(3):155-61.
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Strain QTL Data
Symbol Name Trait
Alc12 Alcohol consumption QTL 12 consumption behavior trait   (VT:0002069)    
Alc13 Alcohol consumption QTL 13 consumption behavior trait   (VT:0002069)    

Additional Information