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Strain: BBDR.LA-(D5Rat98-D5Rat233)/Rhw

Symbol: BBDR.LA-(D5Rat98-D5Rat233)/Rhw
Strain: BBDR.LA-(D5Rat98-D5Rat233)
Substrain: Rhw
RGD ID: 6893530
Citation ID: RRID:RGD_6893530
Ontology ID: RS:0003305
Also Known As: DR.lepr; DR.lepr; BBDR.lepr; BBDR.lepr; BBDR.LA-(D5Rat98-D5Rat233)/Rhw
Type: congenic
Available Source: Not Available
Origination: R. H. William Laboratory, University of Washington, Seattle, Washington
Description: Koletsky rat leptin receptor mutant (lepr) from the LA/N-cp was introgressed into the BBDR/Rhw rats by marker-assisted breeding. This was initiated in 2001 by Dr. Hansen and completed in 2007 at the University of Washington, Seattle.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2595,774,194 - 118,714,492RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0599,421,434 - 123,480,464RGD_MAPPER_PIPELINERnor6.0
Rnor_5.05103,451,053 - 127,341,295RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.45100,017,060 - 124,932,061RGD_MAPPER_PIPELINERGSC3.4





References

References - curated
# Reference Title Reference Citation
1. Differential effects of leptin receptor mutation on male and female BBDR Gimap5-/Gimap5- spontaneously diabetic rats. Moralejo DH, etal., Physiol Genomics. 2010 Mar 3;41(1):9-20. Epub 2009 Dec 8.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D5Rat98)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2595,774,194 - 95,774,399 (+)MAPPER
Rnor_6.0599,421,434 - 99,421,638NCBI
Rnor_5.05103,451,053 - 103,451,257UniSTS
RGSC_v3.45100,017,061 - 100,017,265UniSTS
RGSC_v3.45100,017,060 - 100,017,265RGD
RGSC_v3.15100,022,287 - 100,022,491RGD
Celera594,344,392 - 94,344,614UniSTS
RH 3.4 Map5724.1RGD
RH 3.4 Map5724.1UniSTS
RH 2.0 Map5603.7RGD
SHRSP x BN Map553.5899RGD
Cytogenetic Map5q31UniSTS

Flank 2 / 1 (D5Rat233)
Rat AssemblyChrPosition (strand)Source
mRatBN7.25118,714,244 - 118,714,492 (+)MAPPER
Rnor_6.05123,480,217 - 123,480,464NCBI
Rnor_5.05127,341,048 - 127,341,295UniSTS
RGSC_v3.45124,931,813 - 124,932,061RGD
RGSC_v3.45124,931,814 - 124,932,061UniSTS
RGSC_v3.15124,937,039 - 124,937,287RGD
Celera5117,279,540 - 117,279,787UniSTS
SHRSP x BN Map563.7699RGD
SHRSP x BN Map563.7699UniSTS

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics heterozygous lepr (-/+)or homozygous BBDR (-/-) were lean and metabolically normal 6893459

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-09-05 BBDR.LA-(D5Rat98-D5Rat233)Rhw    BBDR.LA-(D5Rat98-D5Rat233)Rhw    Name updated 68913 APPROVED
2012-09-05 BBDR.LA-(D5Rat98-D5Rat233)/Rhw    BBDR.LA-(D5Rat98-D5Rat233)Rhw    Symbol updated 68687 APPROVED
2012-09-05 BBDR.LA-(D5Rat98-D5Rat233)/Rhw    BBDR.LA-(D5Rat98-D5Rat233)Rhw    Name updated 68913 APPROVED
2012-09-05 BBDR.LA-(D5Rat98-D5Rat233)/Rhw    BBDR.LA-(D5Rat98-D5Rat233)Rhw    Symbol updated 68687 APPROVED
2012-09-05 BBDR.LA-(D5Rat98-D5Rat233)/Rhw    BBDR.LA-(D5Rat98-D5Rat233)Rhw    Name updated 68913 APPROVED