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Strain: WKHT/N

Symbol: WKHT/N
Strain: WKHT
Substrain: N
RGD ID: 68187
RRID: RGD_68187
Ontology ID: RS:0001024
Also known as: RRRC:00189
Type: inbred
Source: Unavailable
Origin: From a cross between SHR and WKY, with selection for high blood pressureand low spontaneous activity (Hendley et al 1988, Knardahl and Hendley 1990, Hendley and Fan, 1992).
Genetic Markers: c.
Coat Color: Albino.
Inbred Generations: F17 (1991)
Last Known Status: Extinct






References


Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Have been used as a model for studying the effects of drugs on aortic aneurysms. Propranololsignificantly reduces the size of abdominal aortic aneurysms independently of the dose and by amechanism which may be unrelated to blood pressure (Slaiby et al, 1994) 1004
strain_characteristics Have been used as a model for studying the effects of drugs on aortic aneurysms. Propranololsignificantly reduces the size of abdominal aortic aneurysms independently of the dose and by amechanism which may be unrelated to blood pressure (Slaiby et al, 1994) 634612
strain_life_disease These are more aggressive and exploratory in a novel environment. 70866

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-03 WKHT/N    WKHT/N    Name updated 68913 APPROVED
2015-04-03 WKHT/N    WKHT/N    Name updated 68913 APPROVED
2013-04-15 WKHT/N    WKHT/N    Name updated 68913 APPROVED
2012-04-19 WKHT/N    WKHT/N    Name updated 68913 APPROVED
2012-04-19 WKHT/N    WKHT/N    Name updated 68913 APPROVED