Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia
Description:
Developed in 1972 at the Institute of Cytology and Genetics, Russian Academy of Sciences (Novosibirsk) by Professor R.I. Salganik from Wistar stock, in contrast to OXYS rat strain by selection for resistance to cataractogenic effect of galactose rich diet and brother-sister mating of highly resistant rats. In 1992, due to new findings, the symbol R was assigned to this strain.
Resistant to cataractogenic effect of galactose-rich diet (Solovyova et al 1975). Good breedingperformance. Monosaccharide transport into the cells and the levels of hydroxyl radical generationand lipid peroxydation are close to that in the healthy Wistar rats.
Resistant to cataractogenic effect of galactose-rich diet (Solovyova et al 1975). Good breedingperformance. Monosaccharide transport into the cells and the levels of hydroxyl radical generationand lipid peroxydation are close to that in the healthy Wistar rats.