R Shoji from a cross of an outbred Jcl:SD rat with spontaneous cataract and WKAH inbred rats. Subsequent brother x sister mating with selecting for cataract resulted in all offspring from the 3rd. generation developing cataract accompanied by microphthalmia which can be observed from the day that the eyes open.
Examination with a slit-lamp microscope shows an adhesion abnormality of the iris on the outsideof the lens in abnormal eyes. The character is caused by a single authsomal recessive genedesignated cms (cataract, microphthalmia and posterior synechia) (Shoji et al 1988).
Examination with a slit-lamp microscope shows an adhesion abnormality of the iris on the outsideof the lens in abnormal eyes. The character is caused by a single authsomal recessive genedesignated cms (cataract, microphthalmia and posterior synechia) (Shoji et al 1988).