Strain Report - Rat Genome Database

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Strain: BDIV

Symbol: BDIV
Strain: BDIV
RGD ID: 67978
Citation ID: RRID:RGD_67978
Ontology ID: RS:0000089
Type: inbred
Available Source: Not Available
Description: Druckrey 1937 from a yellow, pink-eyed strain. Inbred and reduced to one pair after World War II. Crosses with Wistar stock and subsequent inbreeding led to the development of BDII. According to Druckrey (1971), strains BDIII-BDX were then developed from a cross of a single BDI x BDII mating pair, with subsequent selection for coat colour alleles. However, the strains have four different RT1 haplotypes (d, v, l and e) rather than the two that would be expected from such a cross (Stark and Zeiss 1970). The strains can _not_ be regarded as a set of recombinant inbred strains as defined by Bailey (1971), although their definition by coat colour alleles makes the set easily identifiable, and should help (but not guarantee!) to ensure authenticity. According to Druckrey (1971), all strains have a low tumour incidence, with a median life-span of 700-950 days, depending on strain.
Genetic Markers: a,C,h,P
Coat Color: Black hooded.
Inbred Generations: F? +50
Last Known Status: Unknown





References

References - curated
# Reference Title Reference Citation
1. Inbred Strains Festing, MFW, Inbred Strains, The Laboratory Rat, 1979, Baker HK, Lindsey JR, Weisbroth SH, 55-72, Academic Press
2. Functional alterations of the dopaminergic and glutamatergic systems in spontaneous α-synuclein overexpressing rats. Guatteo E, etal., Exp Neurol. 2017 Jan;287(Pt 1):21-33. doi: 10.1016/j.expneurol.2016.10.009. Epub 2016 Oct 20.
3. Rat Strain List M. Festing Rat Strain List
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

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