Strain Report - Rat Genome Database
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Strain: P

Symbol: P
Strain: P
Full Name: alcohol-preferring
RGD ID: 634380
RRID: RGD_634380
Ontology ID: RS:0000635
Alleles: Npy
Type: inbred
Source: Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana
Origin: These were developed at Indiana University for high-alcohol-preferring behavior through bidirectional selective breeding of Wistar rats.
Last Known Status: Unknown

Substrains
P/Iusm





References


Region

Strain QTL Data
Symbol Name Trait
Alc18 Alcohol consumption QTL 18 drinking behavior trait   (VT:0001422)    
Alc19 Alcohol consumption QTL 19 drinking behavior trait   (VT:0001422)    
Alc20 Alcohol consumption QTL 20 drinking behavior trait   (VT:0001422)    
Alc21 Alcohol consumption QTL 21 drinking behavior trait   (VT:0001422)    
Alc8 Alcohol consumption QTL 8 consumption behavior trait   (VT:0002069)    
Sach1 Saccharin preference QTL 1 consumption behavior trait   (VT:0002069)    
Sach2 Saccharin preference QTL 2 consumption behavior trait   (VT:0002069)    
Sach3 Saccharin preference QTL 3 consumption behavior trait   (VT:0002069)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics These have high voluntary oral consumption of alcohol which leads to high blood alcohol. 69704
strain_other strain lacks a polymorphism in Npy gene at position +4666; associated with reduced mRNA levels in this strain 1357412
strain_phys_biochem Vamp2 mRNA is upregulated in frontal cortex compared to NP strain 1358772