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Strain Registration

Strain: F344.GK-(D1Mgh10-D1Rat90)/Swe

Symbol: F344.GK-(D1Mgh10-D1Rat90)/Swe
Strain: F344.GK-(D1Mgh10-D1Rat90)
Substrain: Swe
RGD ID: 631846
Citation ID: RRID:RGD_631846
Ontology ID: RS:0000282
Also Known As: F344.GK-(D1Mgh10-D1Rat90)/Swe; F344.GK-(D1Mgh10-D1Rat90); F344-GK-Niddm1a
Type: congenic
Available Source: Not Available
Origination: Karolinska Institute
Description: Congenic strain originated from an inbred F344/Mcwi strain
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21199,050,459 - 259,647,894RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01217,054,291 - 281,795,785RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01223,910,550 - 289,137,268RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41204,280,278 - 267,111,153RGD_MAPPER_PIPELINERGSC3.4





Experimental Data Annotations    Click to see Annotation Detail View

Rat Strain
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
F344.GK-(D1Mgh10-D1Rat90)/SweRatF344.GK-(D1Mgh10-D1Rat90)/Swe  IEA 7241799 RGD 

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
F344.GK-(D1Mgh10-D1Rat90)/SweRatblood glucose amount  EXP 619677 RGD 


References

References - curated
# Reference Title Reference Citation
1. Pathophysiological and genetic characterization of the major diabetes locus in GK rats. Galli J, etal., Diabetes 1999 Dec;48(12):2463-70.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D1Mgh10)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21199,050,459 - 199,050,587 (+)MAPPER
Rnor_6.01217,054,291 - 217,054,418NCBI
Rnor_5.01223,910,550 - 223,910,677UniSTS
RGSC_v3.41204,280,279 - 204,280,406UniSTS
RGSC_v3.41204,280,278 - 204,280,406RGD
RGSC_v3.11204,433,664 - 204,433,956RGD
Celera1196,613,223 - 196,613,350UniSTS
RH 2.0 Map11099.1RGD

Flank 2 / 1 (D1Rat90)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21259,647,732 - 259,647,894 (+)MAPPER
Rnor_6.01281,795,624 - 281,795,785NCBI
Rnor_5.01289,137,107 - 289,137,268UniSTS
RGSC_v3.41267,110,921 - 267,111,153RGD
RGSC_v3.41267,110,926 - 267,111,087UniSTS
RGSC_v3.11267,322,011 - 267,322,172RGD
Celera1255,291,309 - 255,291,470UniSTS
RH 3.4 Map11708.8RGD
RH 3.4 Map11708.8UniSTS
RH 2.0 Map11313.1999RGD
SHRSP x BN Map1148.15RGD
Strain QTL Data
Symbol Name Trait
Niddm43 Non-insulin dependent diabetes mellitus QTL 43 blood glucose amount   (VT:0000188)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics They have a significant difference in glucose tolerance as compared to the F344 rats 619677

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-17 F344.GK-(D1Mgh10-D1Rat90)/Swe    F344.GK-(D1Mgh10-D1Rat90)/Swe    Name updated 68913 APPROVED
2011-08-17 F344.GK-(D1Mgh10-D1Rat90)/Swe    F344.GK-(D1Mgh10-D1Rat90)/Swe    Name updated 68913 APPROVED