Strain Report - Rat Genome Database

Name: SS.WKY-( D2N35-Mme )/Mco
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain Registration

General

Strain: SS.WKY-(D2N35-Mme)/Mco

Symbol:

SS.WKY-(D2N35-Mme)/Mco

Strain:

SS.WKY-(D2N35-Mme)

Substrain:

Mco

RGD ID:

631607

Citation ID:

RRID:RGD_631607

Ontology ID:

RS:0000919

Previously known as:

S.WKY-D2N35/Nep; Chr 2 congenic; SS/Jr.WKY-(D2N35-Mme)/Mco; SS/Jr.WKY-(D2N35-Nep)/Mco; SS.WKY-(D2N35-Mme)/Mco

Type:

congenic

Source:

Medical College of Ohio, Toledo, Ohio, USA

Origin:

Fragment of the chromosome 2 from WKY was transferred to SS/Jr background and repeated backcross to SS/Jr

Last Known Status:

Unknown

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	147,686,913 - 147,803,808	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	2	153,799,203 - 153,880,910	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	2	173,193,501 - 173,278,946	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	2	153,031,724 - 153,114,515	RGD_MAPPER_PIPELINE	RGSC3.4

Congenic Strains

SS.WKY-(D2N35-Mme),MNS-(D10Mit11-D10M11Mit119)/Mco

Annotation Click to see Annotation Detail View

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

decreased heart weight (IAGP)

decreased systemic arterial systolic blood pressure (IAGP)

Phenotype Values via PhenoMiner Click to see Annotation Detail View

Options:

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Clinical Measurement

systolic blood pressure

heart weight to body weight ratio

References

References - curated

#	Reference Title	Reference Citation
1.	Congenic strains for the blood pressure quantitative trait locus on rat chromosome 2.	Deng AY, etal., Hypertension 1997 Aug;30(2 Pt 1):199-202.
2.	Multiple blood pressure QTL on rat Chromosome 2 defined by congenic Dahl rats.	Garrett MR and Rapp JP, Mamm Genome 2002 Jan;13(1):41-4.
3.	Construction of a double congenic strain to prove an epistatic interaction on blood pressure between rat chromosomes 2 and 10.	Rapp JP, etal., J Clin Invest 1998 Apr 15;101(8):1591-5.
4.	RGD Strain RSO annotation pipeline	RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D2N35)

Rat Assembly	Chr	Position (strand)	Source
Cytogenetic Map	2		RGD

Flank 2 / 1 (Mme)

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	147,686,913 - 147,803,808 (+)	NCBI
mRatBN7.2 Ensembl	2	147,722,086 - 147,803,792 (+)	Ensembl
UTH_Rnor_SHR_Utx	2	154,412,545 - 154,499,268 (+)	NCBI
UTH_Rnor_SHRSP_BbbUtx_1.0	2	152,461,414 - 152,548,760 (+)	NCBI
UTH_Rnor_WKY_Bbb_1.0	2	147,094,065 - 147,181,452 (+)	NCBI
Rnor_6.0	2	153,799,203 - 153,880,910 (+)	NCBI
Rnor_6.0 Ensembl	2	153,803,349 - 153,880,738 (+)	Ensembl
Rnor_5.0	2	173,193,501 - 173,278,946 (+)	NCBI
RGSC_v3.4	2	153,031,724 - 153,114,515 (+)	NCBI
RGSC_v3.1	2	152,981,686 - 153,064,477 (+)	NCBI
Celera	2	142,009,686 - 142,090,693 (+)	NCBI
RH 3.4 Map	2	955.0	RGD
Cytogenetic Map	2	q31	NCBI

Strain QTL Data

Symbol	Name	Trait
Bp90	Blood pressure QTL 90	arterial blood pressure trait (VT:2000000)

Additional Information

RGD Curation Notes

Note Type	Note	Reference
strain_phys_biochem	blood pressure is significantly lower than that of SS/Jr	619640

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: SS.WKY-(D2N35-Mme)/Mco

Mammalian Phenotype

Related Phenotype Data for Term "SS.WKY-(D2N35-Mme)/Mco" (RS:0000919)