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Strain Registration

Strain: WKY/Cfd

Symbol: WKY/Cfd
Strain: WKY
Substrain: Cfd
Full Name: WKY/Cfd
RGD ID: 631275
Citation ID: RRID:RGD_631275
Ontology ID: RS:0001068
Type: inbred
Available Source: Not Available
Origination: Experimental Cardiovascular Biology Laboratory, Institut de Recherches Cliniques de Montreal, 119 Pine Ave W, Montreal, Quebec CA
Description: Substrain of WKY/Cr parents from a colony maintained at the Institut de Recherches Cliniques de Montreal (IRCM), the colony was derived from WKY/Cr parents obtained from Charles River (St. Constant, Quebec CA)
Last Known Status: Unknown





Experimental Data Annotations    Click to see Annotation Detail View

Rat Strain
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
WKY/CfdRatWKY/Cfd  IEA 7241799 RGD 

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
WKY/CfdRatheart left ventricle mass  EXP 1578726 RGD 
WKY/CfdRatheart left ventricle natriuretic peptide A amount  EXP 619659 RGD 

References

References - curated
# Reference Title Reference Citation
1. Functional alterations of the Nppa promoter are linked to cardiac ventricular hypertrophy in WKY/WKHA rat crosses. Deschepper CF, etal., Circ Res 2001 Feb 2;88(2):223-8.
2. Distinct QTLs are linked to cardiac left ventricular mass in a sex-specific manner in a normotensive inbred rat inter-cross. Llamas B, etal., Mamm Genome. 2005 Sep;16(9):700-11. Epub 2005 Oct 20.
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Strain QTL Data
Symbol Name Trait
Cm54 Cardiac mass QTL 54 heart left ventricle mass   (VT:0007031)    
Cm55 Cardiac mass QTL 55 heart left ventricle mass   (VT:0007031)    
Cm56 Cardiac mass QTL 56 heart left ventricle mass   (VT:0007031)    
Cm57 Cardiac mass QTL 57 heart left ventricle mass   (VT:0007031)    
Cm58 Cardiac mass QTL 58 heart left ventricle mass   (VT:0007031)    
Cm59 Cardiac mass QTL 59 heart left ventricle mass   (VT:0007031)    
Lanf1 Left ventricular atrial natriuretic factor QTL 1 heart left ventricle natriuretic peptide A amount   (VT:0010596)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_phys_biochem This strain has higher concentration of atrial natriuretic factor (product of Nppa) in left ventricle tissue than WKHA strain 619659