Strain Report - Rat Genome Database

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Strain: LEXF/Stm

Symbol: LEXF/Stm
Strain: LEXF
Substrain: Stm
RGD ID: 629500
Citation ID: RRID:RGD_629500
Ontology ID: RS:0000534
Type: recombinant_inbred
Source: Saitama Cancer Center Research Institute, 818 Komuro Saitama, Japan
Origin: Recombinant inbred strain derived from LE/Stm (derived from Ben May, Laboratory for Cancer Research, University of Chicago, Chicago IL) and F344/Stm (derived from F344/DuCrlj; Charles River Japan) and then maintained by brother-sister mating.
Last Known Status: Unknown

Experimental Data Annotations    Click to see Annotation Detail View

Rat Strain
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
LEXF/Stm  IEA 7241799 RGD 

Vertebrate Trait
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
testis mass  EXP 1625009 RGD 
thymus integrity trait  EXP 619600 RGD 


References - curated
# Reference Title Reference Citation
1. Propylnitrosourea-induced T-lymphomas in LEXF RI strains of rats: genetic analysis. Lu LM, etal., Br J Cancer 1999 May;80(5-6):855-61.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines
3. The LEXF: a new set of rat recombinant inbred strains between LE/Stm and F344. Shisa H, etal., Mamm Genome 1997 May;8(5):324-7.
4. Quantitative trait loci determining weight reduction of testes and pituitary by diethylstilbesterol in LEXF and FXLE recombinant inbred strain rats. Tachibana M, etal., Exp Anim. 2006 Apr;55(2):91-5.
5. Evaluation of LEXF/FXLE rat recombinant inbred strains for the genetic dissection of complex traits. Voigt B, etal., Physiol Genomics. 2007 Nov 27;.


Strain QTL Data
Symbol Name Trait
Teswt1 Testicular weight QTL 1 testis mass   (VT:1000644)    
Teswt2 Testicular weight QTL 2 testis mass   (VT:1000644)    
Tls1 T-lymphoma susceptibility QTL 1 thymus integrity trait   (VT:0010555)    
Tls2 T-lymphoma susceptibility QTL 2 thymus integrity trait   (VT:0010555)    
Tls3 T-lymphoma susceptibility QTL 3 thymus integrity trait   (VT:0010555)    

Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-06-04 LEXF/Stm    LEXF    Symbol updated 68687 APPROVED
2013-06-04 LEXF/Stm    LEXF    Name updated 68913 APPROVED
2013-06-04 LEXF/Stm    LEXF    Symbol updated 68687 APPROVED
2013-06-04 LEXF/Stm    LEXF    Name updated 68913 APPROVED