Strain Report - Rat Genome Database

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Strain: SHRSP/A3

Symbol: SHRSP/A3
Strain: SHRSP
Substrain: A3
RGD ID: 61116
Citation ID: RRID:RGD_61116
Ontology ID: RS:0000773
Previously known as: SHR/A3; SHR-A3
Type: inbred
Source: Graduate School of Human and Environmental Studies, University of Kyoto, Kyoto, Japan
Origin: Derived from the a substrain of the SHR strain by selective inbreeding for stroke proneness.
Last Known Status: Unknown


References - curated
# Reference Title Reference Citation
1. Natural genetic variation in Stim1 creates stroke in the spontaneously hypertensive rat. Dhande IS, etal., Genes Immun. 2020 May;21(3):182-192. doi: 10.1038/s41435-020-0097-5. Epub 2020 Apr 17.
2. Identification of quantitative trait loci for serum cholesterol levels in stroke-prone spontaneously hypertensive rats. Kato N, etal., Arterioscler Thromb Vasc Biol 2000 Jan;20(1):223-9
3. Defective Store-Operated Calcium Entry Causes Partial Nephrogenic Diabetes Insipidus. Mamenko M, etal., J Am Soc Nephrol. 2016 Jul;27(7):2035-48. doi: 10.1681/ASN.2014121200. Epub 2015 Nov 16.
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Strain QTL Data
Symbol Name Trait
Scl1 Serum cholesterol level QTL 1 blood cholesterol amount   (VT:0000180)    
Scl2 Serum cholesterol level QTL 2 blood cholesterol amount   (VT:0000180)    
Scl3 Serum cholesterol level QTL 3 blood cholesterol amount   (VT:0000180)    

Additional Information