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Strain: DA/Bkl

Symbol: DA/Bkl
Strain: DA
Substrain: Bkl
RGD ID: 61114
Citation ID: RRID:RGD_61114
Ontology ID: RS:0000239
Type: inbred
Available Source: Not Available
Origination: Bantin and Kingman, Fremont, California
Description: Commercially available strain. Maintained at the National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, for production of DA background QTL monocongenic rats and experimental controls.
Last Known Status: Unknown


References - curated
# Reference Title Reference Citation
1. Quantitative trait loci disposing for both experimental arthritis and encephalomyelitis in the DA rat; impact on severity of myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis and antibody isotype pattern. Dahlman I, etal., Eur J Immunol 1998 Jul;28(7):2188-96
2. Identification of a new quantitative trait locus on chromosome 7 controlling disease severity of collagen-induced arthritis in rats. Dracheva SV, etal., Immunogenetics 1999 Aug;49(9):787-91
3. Genetic dissection of a rat model for rheumatoid arthritis: significant gender influences on autosomal modifier loci Furuya T, etal., Hum Mol Genet 2000 Sep 22;9(15):2241-50
4. Identification of four new quantitative trait loci regulating arthritis severity and one new quantitative trait locus regulating autoantibody production in rats with collagen-induced arthritis. Griffiths MM, etal., Arthritis Rheum 2000 Jun;43(6):1278-89
5. Mapping autoimmunity genes. Griffiths MM, etal., Curr Opin Immunol. 1999 Dec;11(6):689-700.
6. Identification of a new non-major histocompatibility complex genetic locus on chromosome 2 that controls disease severity in collagen-induced arthritis in rats. Gulko PS, etal., Arthritis Rheum 1998 Dec;41(12):2122-31
7. Evaluation of quantitative trait loci regulating severity of mycobacterial adjuvant-induced arthritis in monocongenic and polycongenic rats: identification of a new regulatory locus on rat chromosome 10 and evidence of overlap with rheumatoid arthritis susceptibility loci. Joe B, etal., Arthritis Rheum 2002 Apr;46(4):1075-85.
8. Genetic dissection of collagen-induced arthritis in Chromosome 10 quantitative trait locus speed congenic rats: evidence for more than one regulatory locus and sex influences. Joe B, etal., Immunogenetics 2000 Sep;51(11):930-44.
9. Genomic regions controlling corticosterone levels in rats. Potenza MN, etal., Biol Psychiatry 2004 Mar 15;55(6):634-41.
10. A genome scan localizes five non-MHC loci controlling collagen-induced arthritis in rats. Remmers EF, etal., Nat Genet 1996 Sep;14(1):82-5
11. RGD Strain RSO annotation pipeline RGD Automated Pipelines
12. Localization in rats of genetic loci regulating susceptibility to experimental erosive arthritis and related autoimmune diseases. Wilder RL, etal., Transplant Proc 1999 May;31(3):1585-8


Strain QTL Data
Symbol Name Trait
Aia5 Adjuvant induced arthritis QTL 5 joint integrity trait   (VT:0010548)    
Cia1 Collagen induced arthritis QTL 1 joint integrity trait   (VT:0010548)    
Cia10 Collagen induced arthritis QTL 10 joint integrity trait   (VT:0010548)    
Cia11 Collagen induced arthritis QTL 11 joint integrity trait   (VT:0010548)    
Cia12 Collagen induced arthritis QTL 12 joint integrity trait   (VT:0010548)    
Cia14 Collagen induced arthritis QTL 14 joint integrity trait   (VT:0010548)    
Cia2 Collagen induced arthritis QTL 2 joint integrity trait   (VT:0010548)    
Cia24 Collagen induced arthritis QTL 24 joint integrity trait   (VT:0010548)    
Cia3 Collagen induced arthritis QTL 3 joint integrity trait   (VT:0010548)    
Cia4 Collagen induced arthritis QTL 4 joint integrity trait   (VT:0010548)    
Cia5 Collagen induced arthritis QTL 5 joint integrity trait   (VT:0010548)    
Cia8 Collagen induced arthritis QTL 8 joint integrity trait   (VT:0010548)    
Cia9 Collagen induced arthritis QTL 9 joint integrity trait   (VT:0010548)    

Additional Information