Strain Report - Rat Genome Database

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Strain: WKY/NCruk

Symbol: WKY/NCruk
Strain: WKY
Substrain: NCruk
RGD ID: 61097
Citation ID: RRID:RGD_61097
Ontology ID: RS:0001072
Previously known as: WKY/NCrlBR
Type: inbred
Source: Charles River Laboratories UK
Origin: NIH derived strain maintained at the Charles River, United Kingdom.
Last Known Status: Unknown


References - curated
# Reference Title Reference Citation
1. Quantitative trait loci for cellular defects in glucose and fatty acid metabolism in hypertensive rats. Aitman TJ, etal., Nat Genet 1997 Jun;16(2):197-201
2. Kidney specificity of rat chromosome 1 blood pressure quantitative trait locus region. Clemitson JR, etal., Hypertension 2002 Sep;40(3):292-7.
3. Genetic dissection of region around the Sa gene on rat chromosome 1: evidence for multiple loci affecting blood pressure. Frantz S, etal., Hypertension 2001 Aug;38(2):216-21.
4. Successful isolation of a rat chromosome 1 blood pressure quantitative trait locus in reciprocal congenic strains Frantz SA, etal., Hypertension 1998 Oct;32(4):639-46
5. RGD Strain RSO annotation pipeline RGD Automated Pipelines
6. Genetic determination of cardiac mass in normotensive rats: results from an F344xWKY cross. Sebkhi A, etal., Hypertension 1999 Apr;33(4):949-53.
7. Right ventricular hypertrophy secondary to pulmonary hypertension is linked to rat chromosome 17: evaluation of cardiac ryanodine Ryr2 receptor as a candidate. Zhao L, etal., Circulation 2001 Jan 23;103(3):442-7.


Strain QTL Data
Symbol Name Trait
Bp29 Blood pressure QTL 29 arterial blood pressure trait   (VT:2000000)    
Cm15 Cardiac mass QTL 15 heart right ventricle mass   (VT:0007033)    
Cm25 Cardiac mass QTL 25 heart left ventricle mass   (VT:0007031)    
Gluco16 Glucose level QTL 16 adipocyte glucose uptake trait   (VT:0004185)    
Gluco17 Glucose level QTL 17 adipocyte glucose uptake trait   (VT:0004185)    
Gluco3 Glucose level QTL 3 adipocyte glucose uptake trait   (VT:0004185)    
Gluco4 Glucose level QTL 4 adipocyte glucose uptake trait   (VT:0004185)    
Gluco5 Glucose level QTL 5 adipocyte free fatty acid secretion trait   (VT:0010465)    

Additional Information