Strain Report - Rat Genome Database

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Strain: LN/MavRrrc

Symbol: LN/MavRrrc
Strain: LN
Substrain: MavRrrc
Full Name: lyon normotensive
RGD ID: 61015
RRID: RGD_61015
Ontology ID: RS:0000559
Also known as: RRRC:0058
Type: inbred
Source: Rat Resource and Research Center
Origin: (taken from Lyon Hypertensive entry, see LH) In 1969 outbred Sprague-Dawley rats were selected for high systolic blood pressure using an indirect plethysmographic technique in pre-warmed unrestrained conscious rats. Three pairs were originally selected, and selection was continued with brother x sister mating. Strain LN was maintained as a normotensive control, and LL as a hypotensive strain. (see Vincent et al 1984, and Vincent and Sassard, 1994 for reviews).
Genetic Markers: c
Coat Color: Albino
Inbred Generations: F27
Last Known Status: Cryopreserved Embryo; Cryopreserved Sperm



Strain QTL Data
Symbol Name Trait
Bp357 Blood pressure QTL 357 arterial blood pressure trait   (VT:2000000)    
Bp50 Blood pressure QTL 50 arterial blood pressure trait   (VT:2000000)    
BpQTLCluster2 Blood pressure QTL cluster 2 arterial blood pressure trait   (VT:2000000)    
Damaging Variants
Number of Damaging Variants
LN/MavRrrc (ICL) 662
LN/MavRrrc (KNAW) 800
LN/MavRrrc (RGD) 1095

Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-01-11 LN/MavRrrc  lyon normotensive  LN  lyon normotensive  Symbol and/or name change 68913 APPROVED