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Strain: NEDH

Symbol: NEDH
Strain: NEDH
RGD ID: 61001
Citation ID: RRID:RGD_61001
Ontology ID: RS:0000603
Type: inbred
Source: Not Available
Origin: Inbred by S. Warren at New England Deaconess Hospital, from Slonaker colony (University of Chicago ca. 1928). To Simonsen Laboratories in 1985 via B. Hoffman, Veterans Administration Medical Center, Palo Alto, CA. To Mollegaard in 1987.
Coat Color: Albino
Inbred Generations: At Sim, F?+F8. At Mol, F?+F5.
Last Known Status: Unknown

Substrains
NEDH/K
NEDH/KSim






References

References - curated
# Reference Title Reference Citation
1. Inbred Strains Festing, MFW, Inbred Strains, The Laboratory Rat, 1979, Baker HK, Lindsey JR, Weisbroth SH, 55-72, Academic Press
2. Update to previous Strain Data Festing, MFW, Personal Communication Update, Feb-2000
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease Pheochromocytomas develop spontaneously in 59% of 700-900 day-old males and in 81% of males 900 days or older. Almost always arise in the adrenal medulla, and about 50% occur bilaterally (Manger et al 1985). NEDH carrying transplanted pheochromocytomas have plasma norepinephrine concentrations 40-fold higher than age-matched controls, and provide a model of cardiomyopathy and other effects of prolonged exposure to catecholamines (Prokocimer et al 1987, 1988, Rosenbaum et al 1986, 1987, 1988). 1004
strain_life_disease Pheochromocytomas develop spontaneously in 59% of 700-900 day-old males and in 81% of males 900 days or older. Almost always arise in the adrenal medulla, and about 50% occur bilaterally (Manger et al 1985). NEDH carrying transplanted pheochromocytomas have plasma norepinephrine concentrations 40-fold higher than age-matched controls, and provide a model of cardiomyopathy and other effects of prolonged exposure to catecholamines (Prokocimer et al 1987, 1988, Rosenbaum et al 1986, 1987, 1988). 634612
strain_reproduction Good reproductive performance. 1004
strain_reproduction Good reproductive performance. 634612