Strain Report - Rat Genome Database

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Strain: SS-Tgfb1em3Mcwi+/-

Symbol: SS-Tgfb1em3Mcwi+/-
Strain: SS-Tgfb1em3-/Tgfb1em3+/-
Substrain: Mcwi
Full Name: SS-Tgfb1em3Mcwi+/Tgfb1em3Mcwi-
RGD ID: 5688119
Citation ID: RRID:RGD_5688119
Ontology ID: RS:0003129
Previously known as: SS-Tgfb1em3Mcwi-/+; SS-Tgfb1em3Mcwi/2Mcwi; SS-Tgfb1em3Mcwi/2Mcwi; SS-Tgfb1em3Mcwi-/Tgfb1em3Mcwi+; SS-Tgfb1em3Mcwi-/Tgfb1em3Mcwi+; SS-Tgfb1em3Mcwi-/+
Type: mutant
Source: PhysGen Knockouts
Origin: ZFN mutant founders were backcrossed with SS/JrHsdMcwi to get heterozygous offsprings which were intercrossed and offsprings maintained heterozygous breeders.
Genetic Status: Heterozygous
Last Known Status: Cryopreserved Sperm (as of 2021-08-24)


References - curated
# Reference Title Reference Citation
1. Heterozygous knockout of transforming growth factor-ß1 protects Dahl S rats against high salt-induced renal injury. Chen CC, etal., Physiol Genomics. 2013 Feb 4;45(3):110-8. doi: 10.1152/physiolgenomics.00119.2012. Epub 2012 Dec 18.
2. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
3. PhysGen Knockouts PhysGen Knockout strains
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-08-24 SS-Tgfb1em3Mcwi+/-  SS-Tgfb1em3Mcwi+/Tgfb1em3Mcwi-  SS-Tgfb1em3Mcwi-/+  SS-Tgfb1em3Mcwi-/Tgfb1em3Mcwi+  Symbol and/or name change 68913 APPROVED
2014-03-31 SS-Tgfb1em3Mcwi-/+  SS-Tgfb1em3Mcwi-/Tgfb1em3Mcwi+  SS-Tgfb1em3Mcwi-/+  SS-Tgfb1em3Mcwi-/Tgfb1em3Mcwi+  Symbol and/or name change 68913 APPROVED