Strain Report - Rat Genome Database

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Strain: SS-Ncf2em1Mcwi+/+

Symbol: SS-Ncf2em1Mcwi+/+
Strain: SS-Ncf2em1+/Ncf2em1+
Substrain: Mcwi
Full Name: SS-Ncf2em1Mcwi+/Ncf2em1Mcwi+
RGD ID: 5688069
Citation ID: RRID:RGD_5688069
Ontology ID: RS:0003179
Previously known as: SS-Ncf2em1Mcwi+/+; SS-Ncf2em1Mcwi/3Mcwi; SS-Ncf2em1Mcwi/3Mcwi; SS-Ncf2em1Mcwi+/Ncf2em1Mcwi+
Type: mutant
Source: PhysGen Knockouts
Origin: ZFN mutant founders were backcrossed with SS/JrHsdMcwi to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders.
Genetic Status: Wild Type
Last Known Status: Unknown


References - curated
# Reference Title Reference Citation
1. Increased expression of NAD(P)H oxidase subunit p67(phox) in the renal medulla contributes to excess oxidative stress and salt-sensitive hypertension. Feng D, etal., Cell Metab. 2012 Feb 8;15(2):201-8. doi: 10.1016/j.cmet.2012.01.003.
2. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
3. PhysGen Knockouts PhysGen Knockout strains
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-31 SS-Ncf2em1Mcwi+/+  SS-Ncf2em1Mcwi+/Ncf2em1Mcwi+  SS-Ncf2em1Mcwi+/+  SS-Ncf2em1Mcwi+/Ncf2em1Mcwi+  Symbol and/or name change 68913 APPROVED