Strain Report - Rat Genome Database

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Strain: WKY/Kiha

Symbol: WKY/Kiha
Strain: WKY
Substrain: Kiha
RGD ID: 4142544
RRID: RGD_4142544
Ontology ID: RS:0002470
Also known as: HA-WKY;NBRP Rat No: 0612
Type: mutant
Source: National BioResource Project for the Rat in Japan
Origin: A WKY rat showing higher serum adiponectin concentration was found in Department of Pathology, Kinki University School of Medicine. In 1974, this strain was transferred from Dr. Okamoto to Kyoto University.
Coat Color: Albino
Inbred Generations: F32
Last Known Status: Cryopreserved Embryo





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Mammalian Phenotype

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Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics WKY/Kiha (HA-WKY) rats exhibit about 4-fold higher serum adiponectin concentration at 6 weeks of age compared with that of WKY/Izm. When fed high-fat diets, WKY/Kiha rats show hyperinsulinemia and severe hypercholesterolemia. The lack of adiponectin binding to skeletal muscle seems to cause these phenotypes of WKY/Kiha. 1302502

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-05-31 WKY/Kiha    WKY/Kiha    Name updated 68913 APPROVED
2012-05-31 WKY/Kiha    WKY/Kiha    Name updated 68913 APPROVED
2011-07-26 WKY/Kiha    WKY/Kiha    Name updated 68913 APPROVED
2011-07-26 WKY/Kiha    WKY/Kiha    Name updated 68913 APPROVED