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Strain Registration

Strain: SD-Esr1em1Bra+/+

Symbol: SD-Esr1em1Bra+/+
Strain: SD-Esr1em1+/+
Substrain: Bra
RGD ID: 405650195
Citation ID: RRID:RGD_405650195
Ontology ID: RS:0005327
Also Known As: SD-Esr1^[em1Bra+/+]
Type: mutant
Available Source: Department of Medicine, Division of Pulmonary, Critical Care, Sleep and Occupational Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Origination: Genome Editing and Animal Models, University of Wisconin-Madison
Description: This is the wild type littermate from the crossing of heterozygous Esr1 mutant rats. This wild type littermate rat was used as a control for the homozygous mutant SD-Esr1em1-/- (RGD:405649860) in estrogen receptor study.
Genetic Status: Wild Type
Last Known Status: Unknown






References

References - curated
# Reference Title Reference Citation
1. 17β-Estradiol and estrogen receptor α protect right ventricular function in pulmonary hypertension via BMPR2 and apelin. Frump AL, etal., J Clin Invest. 2021 Mar 15;131(6):e129433. doi: 10.1172/JCI129433.

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