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Strain Registration

Strain: HiSER/Hat

Symbol: HiSER/Hat
Strain: HiSER
Substrain: Hat
Full Name: Hirosaki small-eye rat
RGD ID: 38676461
Citation ID: RRID:RGD_38676461
Ontology ID: RS:0005040
Type: mutant
Available Source: Not Available
Origination: Depart of Biochemistry and Genome Biology, Hirosaki Univer-sity School of Medicine
Description: HiSER was established in 2013 as a spontaneous mutant of Sprague-Dawley rat. This mutant strain has retinal detachment and the disease is progressively exacerbated. The muation is autosomal recessive and is suggested to be due to deletion of the crystallin gene Cryba1.
Genetic Status: Homozygous
Last Known Status: Unknown





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References

References - curated
# Reference Title Reference Citation
1. Establishment of a recessive mutant small-eye rat with lens involution and retinal detachment associated with partial deletion and rearrangement of the Cryba1 gene. Yamada T, etal., Biochem J. 2015 Oct 15;471(2):293-305. doi: 10.1042/BJ20150165. Epub 2015 Aug 24.

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