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Strain Registration

Strain: SHR-Prdx2em1Izm

Symbol: SHR-Prdx2em1Izm
Strain: SHR-Prdx2em1
Substrain: Izm
RGD ID: 38599208
Citation ID: RRID:RGD_38599208
Ontology ID: RS:0004901
Also Known As: NBRP Rat No: 0814; SHR Prdx2 KO1; SHR-KO(Prdx2 c.6_13del7)Izm; SHR-Prdx2^[em1Izm]
Type: mutant
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: This strain is established at Kyoto University: By CRISPR/Cas9 system, mutation was introduced in Peroxiredoxin-2 (Prdx2) gene of SHR/Izm rat. This KO rat strain has 7-bp deletion (5'-CTCCGGC-3', c.6_13del7) in the exon2 of Prdx2 gene. Target sequence is 5?-CCTCCGGCAACGCGCACATCGGA-3?(PAM sequence:CCT).
Coat Color: white
Last Known Status: Cryopreserved Sperm (as of 2020-09-15)





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References

References - curated
# Reference Title Reference Citation
1. Effects of the Prdx2 depletion on blood pressure and life span in spontaneously hypertensive rats. Mahal Z, etal., Hypertens Res. 2019 May;42(5):610-617. doi: 10.1038/s41440-019-0207-9. Epub 2019 Jan 17.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP

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